Results 21 to 30 of about 4,080,669 (137)

A review of proton therapy – Current status and future directions

open access: yesPrecision Radiation Oncology, 2022
The original rationale for proton therapy was its highly conformal depth‐dose distributions compared to photons, which allow greater sparing of normal tissues and escalation of tumor doses, thus potentially improving outcomes.
Radhe Mohan
doaj   +1 more source

Daily adaptive proton therapy: Feasibility study of detection of tumor variations based on tomographic imaging of prompt gamma emission from proton–boron fusion reaction

open access: yesNuclear Engineering and Technology, 2022
In this study, the images of specific prompt gamma (PG)-rays of 719 keV emitted from proton–boron reactions were analyzed using single-photon emission computed tomography (SPECT). Quantitative evaluation of the images verified the detection of anatomical
Min-Geon Choi   +7 more
doaj   +1 more source

Commissioning an in-room mobile CT for adaptive proton therapy with a compact proton system. [PDF]

open access: yesJ Appl Clin Med Phys, 2018
Oliver JA   +7 more
europepmc   +2 more sources

Proton Beam Therapy and Photon-Based Magnetic Resonance Image-Guided Radiation Therapy: The Next Frontiers of Radiation Therapy for Hepatocellular Carcinoma

open access: yesTechnology in Cancer Research & Treatment, 2023
External beam radiation therapy (EBRT) has increasingly been utilized in the treatment of hepatocellular carcinoma (HCC) due to technological advances with positive clinical outcomes. Innovations in EBRT include improved image guidance, motion management,
Peter Zaki MD   +5 more
doaj   +1 more source

Impact of heterogeneities on lateral penumbra in uniform scanning proton therapy [PDF]

open access: yes, 2013
Purpose: In the treatment planning of uniform scanning proton therapy, an aperture block is designed for each beam with a margin, which typically includes the lateral penumbra measured in water (homogenous) medium.
Rana, Suresh; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City   +1 more
core   +1 more source

Clinical implementation and validation of an automated adaptive workflow for proton therapy

open access: yesPhysics and Imaging in Radiation Oncology, 2022
Background and purpose: Treatment quality of proton therapy can be monitored by repeat-computed tomography scans (reCTs). However, manual re-delineation of target contours can be time-consuming.
Vicki Trier Taasti   +8 more
doaj   +1 more source

A Review of the Robust Optimization Process and Advances with Monte Carlo in the Proton Therapy Management of Head and Neck Tumors [PDF]

open access: yesInternational Journal of Particle Therapy, 2021
In intensity-modulated proton therapy, robust optimization processes have been developed to manage uncertainties associated with (1) range, (2) setup, (3) anatomic changes, (4) dose calculation, and (5) biological effects.
Xiaodong Zhang, PhD
doaj   +1 more source

Planning and Treatment Recommendations for Breast Proton Therapy From a Single Center's Experience

open access: yesAdvances in Radiation Oncology, 2023
Purpose: Proton therapy use for breast cancer has grown due to advantages in coverage and potentially reduced late toxicities compared with conventional radiation therapy.
Rachel B. Ger, PhD   +6 more
doaj   +1 more source

Image Guided Adaptive Therapy Strategies for Robustly Optimized Intensity Modulated Proton Therapy [PDF]

open access: yes, 2023
Introducing anatomical changes to a patient during intensity-modulated proton therapy (IMPT) can cause inadequate target coverage and overdosage to normal tissues.
Xu, Yihang
core   +1 more source

Image-Guided Proton Therapy: A Comprehensive Review

open access: yes, 2023
Image guidance for radiation therapy can improve the accuracy of the delivery of radiation, leading to an improved therapeutic ratio. Proton radiation is able to deliver a highly conformal dose to a target due to its advantageous dosimetric properties ...
Jason M. Slater   +2 more
core   +1 more source

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