Results 21 to 30 of about 3,973,865 (282)

Optimizing quality assurance CT schedules during adaptive proton therapy for enhanced patient care. [PDF]

J Appl Clin Med Phys
Purpose This study aims to optimize the frequency of routine quality assurance CT (QACT) scans in proton beam therapy (PBT) for brain, head and neck (HN), and prostate treatments. The goal is to enhance treatment efficiency without compromising treatment
Biswal NC, Zakhary MJ, Parchur AK, Mogilnay R, Ferris MJ, Nichols EM, Witek ME, Yi B.   +7 more
europepmc   +2 more sources

Facilitating MR-Guided Adaptive Proton Therapy in Children Using Deep Learning-Based Synthetic CT. [PDF]

Int J Part Ther, 2022
Purpose: To determine whether self-attention cycle-generative adversarial networks (cycle-GANs), a novel deep-learning method, can generate accurate synthetic computed tomography (sCT) to facilitate adaptive proton therapy in children with brain tumors ...
Wang C, Uh J, Merchant TE, Hua CH, Acharya S.   +4 more
europepmc   +2 more sources

Enhancing CBCT-based CT synthesis using planning MRI in adaptive proton therapy for head cancer: A deep learning approach. [PDF]

J Appl Clin Med Phys
Background Proton therapy (PT) is recognized as a superior treatment for head cancer (HC) due to its precision and minimal damage to surrounding healthy tissues, relying on computed tomography (CT) data for dose calculations. Adaptive proton therapy (APT)
Molina-Maza JM, Viar-Hernandez D, Rodriguez-Gonzalez B, Sequeiro-Gonzalez J, Vera-Sanchez JA, Mazal A, Malpica N, Torrado-Carvajal A, Perez-Moreno JM, Rodriguez-Vila B.   +9 more
europepmc   +2 more sources

Online adaptive dose restoration in intensity modulated proton therapy of lung cancer to account for inter-fractional density changes

Physics and Imaging in Radiation Oncology, 2020
Background and purpose: In proton therapy, inter-fractional density changes can severely compromise the effective delivery of the planned dose. Such dose distortion effects can be accounted for by treatment plan adaptation, that requires considerable ...
Edmond Sterpin, Xavier Geets
exaly   +3 more sources

Clinical implementation and validation of an automated adaptive workflow for proton therapy

Physics and Imaging in Radiation Oncology, 2022
Background and purpose: Treatment quality of proton therapy can be monitored by repeat-computed tomography scans (reCTs). However, manual re-delineation of target contours can be time-consuming.
Vicki Trier Taasti, Colien Hazelaar, Femke Vaassen, Ana Vaniqui, Karolien Verhoeven, Frank Hoebers, Wouter van Elmpt, Richard Canters, Mirko Unipan   +8 more
doaj   +4 more sources

Commissioning an in-room mobile CT for adaptive proton therapy with a compact proton system. [PDF]

J Appl Clin Med Phys, 2018
AbstractPurposeTo describe the commissioning of AIRO mobile CT system (AIRO) for adaptive proton therapy on a compact double scattering proton therapy system.MethodsA Gammex phantom was scanned with varying plug patterns, table heights, and mAs on a CT simulator (CT Sim) and on the AIRO.
Oliver JA, Zeidan O, Meeks SL, Shah AP, Pukala J, Kelly P, Ramakrishna NR, Willoughby TR.   +7 more
europepmc   +3 more sources

Investigation of intra-fractionated range guided adaptive proton therapy (RGAPT): II. Range-shift compensated on-line treatment adaptation and verification. [PDF]

Phys Med Biol
We previously proposed range-guided adaptive proton therapy (RGAPT) that uses mid-range treatment beams as probing beams and intra-fractionated range measurements for online adaptation. In this work, we demonstrated experimental verification and reported
Chen M, Yang D, Zhu XR, Ma L, Grosshans DR, Shao Y, Lu W.   +6 more
europepmc   +2 more sources

Feasibility study on using low dose CT for adaptive proton therapy.

Medical Dosimetry
In adaptive proton therapy, imaging is imperative for daily patient setup, monitoring anatomical changes, dose prediction, and replanning. However, utilizing cone-beam computed tomography (CBCT) is limited by artifacts and inaccurate Hounsfield units ...
Sydney Shindler, Tie-Zhi Zhang, Tong Zhu, Bao-Zhou Sun, Geoffrey D. Hugo, Arash Darafsheh, Stephanie M. Perkins, Tianyu Zhao, Yao Hao   +8 more
semanticscholar   +3 more sources

Exploration of an adaptive proton therapy strategy using CBCT with the concept of digital twins. [PDF]

Phys Med Biol
Objective. This study aims to develop a digital twin (DT) framework to achieve adaptive proton prostate stereotactic body radiation therapy (SBRT) with fast treatment plan selection and patient-specific clinical target volume (CTV) setup uncertainty ...
Chang CW, Tian Z, Qiu RLJ, Scott Mcginnis H, Bohannon D, Patel P, Wang Y, Yu DS, Patel SA, Zhou J, Yang X.   +10 more
europepmc   +2 more sources

Cone-Beam CT Images as an Indicator of QACT During Adaptive Proton Therapy of Extremity Sarcomas. [PDF]

Int J Part Ther
Purpose Periodic quality assurance CTs (QACTs) are routine in proton beam therapy. In this study, we tested whether the necessity for a QACT could be determined by evaluating the change in beam path length (BPL) on daily cone-beam CT (CBCT). Patients and
Biswal NC, Zhang B, Nichols E, Witek ME, Regine WF, Yi B.   +5 more
europepmc   +2 more sources