A Review of the Robust Optimization Process and Advances with Monte Carlo in the Proton Therapy Management of Head and Neck Tumors [PDF]
International Journal of Particle Therapy, 2021 In intensity-modulated proton therapy, robust optimization processes have been developed to manage uncertainties associated with (1) range, (2) setup, (3) anatomic changes, (4) dose calculation, and (5) biological effects.
Xiaodong Zhang, PhD
doaj +1 more source
The grid-dose-spreading algorithm for dose distribution calculation in heavy charged particle radiotherapy [PDF]
, 2007 A new variant of the pencil-beam (PB) algorithm for dose distribution calculation for radiotherapy with protons and heavier ions, the grid-dose spreading (GDS) algorithm, is proposed.
Ahnesjö +29 more
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Planning and Treatment Recommendations for Breast Proton Therapy From a Single Center's Experience
Advances in Radiation Oncology, 2023 Purpose: Proton therapy use for breast cancer has grown due to advantages in coverage and potentially reduced late toxicities compared with conventional radiation therapy.
Rachel B. Ger, PhD +6 more
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Treatment planning optimisation in proton therapy [PDF]
, 2013 The goal of radiotherapy is to achieve uniform target coverage while sparing normal tissue. In proton therapy, the same sources of geometric uncertainty are present as in conventional radiotherapy.
Burnet, NG, Lomax, AJ, McGowan, SE
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Dose ratio proton radiography using the proximal side of the Bragg peak [PDF]
, 2015 Purpose: In recent years there has been a movement towards single-detector proton radiography, due to its potential ease of implementation within the clinical environment.
A. Gibson +54 more
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First Application of Predictive Model to Assist Adaptive Proton Therapy [PDF]
International Journal of Radiation Oncology*Biology*Physics, 2021 PURPOSE/OBJECTIVE(S) To assess a model to predict anatomical changes in head and neck cancer patients and explore the applicability of the model as a tool for adaptive replanning in intensity-modulated proton therapy (IMPT). MATERIALS/METHODS 20 radiotherapy patients with nasopharyngeal cancer were included in this retrospective study. Each patient had
Y. Zhang +5 more
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Adaptive step size algorithm to increase efficiency of proton macro Monte Carlo dose calculation
Radiation Oncology, 2019 Purpose To provide fast and accurate dose calculation in voxelized geometries for proton radiation therapy by implementing an adaptive step size algorithm in the proton macro Monte Carlo (pMMC) method.
Reto Kueng +7 more
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Physics and Imaging in Radiation Oncology, 2021 Background and purpose: The more localized dose deposition of proton therapy (PT) compared to photon therapy might allow a reduction in treatment-related side effects but induces additional challenges to address. The aim of this study was to evaluate the
Stéphane Niyoteka +7 more
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Transplantable melanomas in hamsters and gerbils as models for human melanoma : sensitization in melanoma radiotherapy : from animal models to clinical trials [PDF]
, 2018 The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption
Andrzej Słominski +11 more
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