Results 51 to 60 of about 44,966 (284)

Fraction-variant beam orientation optimization for non-coplanar IMRT

, 2017
Conventional beam orientation optimization (BOO) algorithms for IMRT assume that the same set of beam angles is used for all treatment fractions. In this paper we present a BOO formulation based on group sparsity that simultaneously optimizes non ...
Nguyen, Dan, O'Connor, Daniel, Ruan, Dan, Sheng, Ke, Yu, Victoria   +4 more
core   +1 more source

Treatment of helicobacter pylori infection in atrophic gastritis [PDF]

, 2018
Helicobacter pylori (Hp) is a major human pathogen causing chronic, progressive gastric mucosal damage and is linked to gastric atrophy and cancer. Hp-positive individuals constitute the major reservoir for transmission of infection.
Annibale, B, Carabotti, M, Lahner, E
core   +1 more source

Respiratory organ motion in interventional MRI : tracking, guiding and modeling [PDF]

, 2014
Respiratory organ motion is one of the major challenges in interventional MRI, particularly in interventions with therapeutic ultrasound in the abdominal region. High-intensity focused ultrasound found an application in interventional MRI for noninvasive
Celicanin, Zarko
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Dosimetric impact of gastrointestinal air column in radiation treatment of pancreatic cancer [PDF]

, 2017
OBJECTIVE: Dosimetric evaluation of air column in gastrointestinal (GI) structures in intensity modulated radiation therapy (IMRT) of pancreatic cancer.
Cardenes, Higinia R., Corn, Jonathan B., Das, Indra J., Estabrook, Neil C., Ewing, Marvene M.   +4 more
core   +1 more source

Adaptive Proton Therapy Using CBCT-Guided Digital Twins

ArXiv
This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a leading option for external beam radiotherapy due to its effectiveness and reduced treatment duration.
Chang, Chih-Wei, Tian, Zhen, Qiu, Richard L. J., McGinnis, H. Scott, Bohannon, Duncan, Patel, Pretesh, Wang, Yinan, Yu, David S., Patel, Sagar A., Zhou, Jun, Yang, Xiaofeng   +10 more
openaire   +3 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

A Two-Plane Proton Radiography System Using ATLAS IBL Pixel-Detector Modules

Instruments
Accurate knowledge of a patient’s anatomy during every treatment fraction in proton therapy is an important prerequisite to ensure a correct dose deposition in the target volume.
Hendrik Speiser, Claus Maximillian Bäcker, Johannes Esser, Alina Hild, Marco Iampieri, Ann-Kristin Lüvelsmeyer, Annsofie Tappe, Helen Thews, Kevin Kröninger, Jens Weingarten   +9 more
doaj   +1 more source

Evolution of a beam dynamics model for the transport lines in a proton therapy facility

, 2017
Despite the fact that the first-order beam dynamics models allow an approximated evaluation of the beam properties, their contribution is essential during the conceptual design of an accelerator or beamline.
Adelmann, A., Baumgarten, C., Frey, M., Gerbershagen, A., Meer, D., Rizzoglio, V., Schippers, J. M.   +6 more
core   +2 more sources

Potential benefits of adaptive intensity‐modulated proton therapy in nasopharyngeal carcinomas

Journal of Applied Clinical Medical Physics, 2020
AbstractPurposeTo investigate potential advantages of adaptive intensity‐modulated proton beam therapy (A‐IMPT) by comparing it to adaptive intensity‐modulated X‐ray therapy (A‐IMXT) for nasopharyngeal carcinomas (NPC).MethodsTen patients with NPC treated with A‐IMXT (step and shoot approach) and concomitant chemotherapy between 2014 and 2016 were ...
Minatogawa, Hideki, Yasuda, Koichi, Dekura, Yasuhiro, Takao, Seishin, Matsuura, Taeko, Yoshimura, Takaaki, Suzuki, Ryusuke, Yokota, Isao, Fujima, Noriyuki, Onimaru, Rikiya, Shimizu, Shinichi, Aoyama, Hidefumi, Shirato, Hiroki   +12 more
openaire   +3 more sources