Results 61 to 70 of about 3,973,865 (282)

Image-Guided Proton Therapy: A Comprehensive Review

, 2023
Image guidance for radiation therapy can improve the accuracy of the delivery of radiation, leading to an improved therapeutic ratio. Proton radiation is able to deliver a highly conformal dose to a target due to its advantageous dosimetric properties ...
Jason M. Slater, Shelby A. Lane, Gary Y. Yang   +2 more
core   +1 more source

Real-time adaptive proton therapy: An AI-based spatio-temporal mono-energetic dose calculation model (CC-LSTM)

Comput. Biol. Medicine
PURPOSE To develop a fully AI-based dose estimation model capable of learning and estimating single pencil beam dose distributions, and to verify its performance by testing the model's generalizability on unseen, previously delivered treatment plans ...
A. Neishabouri, J. Bauer, A. Abdollahi, J. Debus, A. Mairani   +4 more
semanticscholar   +1 more source

Adaptive Proton Therapy in Head and Neck Cancer

, 2021
Anatomic and dosimetric changes occur in head and neck cancer during fractionated proton radiotherapy, and the actual dose received by patient is considerably different from original plan. Adaptive radiotherapy aims to modify treatment according to changes that occur during proton therapy.
openaire   +2 more sources

A survey of practice patterns for adaptive particle therapy for interfractional changes

Physics and Imaging in Radiation Oncology, 2023
Background and purpose: Anatomical changes may compromise the planned target coverage and organs-at-risk dose in particle therapy. This study reports on the practice patterns for adaptive particle therapy (APT) to evaluate current clinical practice and ...
Petra Trnkova, Ye Zhang, Toshiyuki Toshito, Ben Heijmen, Christian Richter, Marianne C. Aznar, Francesca Albertini, Alessandra Bolsi, Juliane Daartz, Antje C. Knopf, Jenny Bertholet   +10 more
doaj   +1 more source

Feasibility of Monte Carlo dropout-based uncertainty maps to evaluate deep learning-based synthetic CTs for adaptive proton therapy.

Medical Physics (Lancaster), 2023
BACKGROUND Deep learning has shown promising results to generate MRI-based synthetic CTs and to enable accurate proton dose calculations on MRIs.
A. Galapon, A. Thummerer, J. Langendijk, D. Wagenaar, S. Both   +4 more
semanticscholar   +1 more source

Treatment planning study comparing proton therapy, RapidArc and intensity modulated radiation therapy for a synchronous bilateral lung cancer case

, 2014
Purpose: The main purpose of this study is to perform a treatment planning study on a synchronous bilateral non-small cell lung cancer case using three treatment modalities: uniform scanning proton therapy, RapidArc, and intensity modulated radiation ...
Zheng, Yuanshui; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, OK, USA., Zhao, Li; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, OK, USA., Risalvato, Dina; Department of Medical Dosimetry, ProCure Proton Therapy Center, Oklahoma City, Oklahoma, USA., Vargas, Carlos; Radiation Oncology, Proton Collaborative Group (PCG), Bloomington, Indiana, USA., Rana, Suresh; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, OK, USA., Pokharel, Shyam; Department of Medical Physics, 21st Century Oncology, Fort Myers, Florida, USA., Cersonsky, Nancy; Department of Radiation Oncology, ProCure Proton Therapy Center, Oklahoma City, Oklahoma, USA.   +6 more
core   +1 more source

Advances in proton therapy technology and global clinical applications

Frontiers in Oncology
Proton therapy, by leveraging its unique physical characteristic of the Bragg peak, enables high-precision dose delivery to the tumor target while effectively protecting surrounding normal tissues, and has become an important representative of advanced ...
Qi Zhang, Wencui Yang, Lina Tan, Xiangyu Guo, Tao Wang, Pengfei Zhu, Zhouchen Jing, Lei Ma, Jun Hou   +8 more
doaj   +1 more source

Potential margin reduction in prostate cancer proton therapy with prompt gamma imaging for online treatment verification

Physics and Imaging in Radiation Oncology, 2023
The potential of proton therapy is currently limited due to large safety margins. We estimated the potential reduction of clinical margins when using prompt gamma imaging (PGI) for online treatment verification of prostate cancer.
Stefanie Bertschi, Kristin Stützer, Jonathan Berthold, Julian Pietsch, Julien Smeets, Guillaume Janssens, Christian Richter   +6 more
doaj   +1 more source

Proton accelerators

, 2012
Until the 1990s proton therapy was performed in nuclear physics laboratories that were equipped with a particle accelerator. Typically an (isochronous) cyclotron or a synchrocyclotron was available, and in most cases the medical program had to compete ...
Schippers, Marco (author)
core   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source