Results 61 to 70 of about 4,080,669 (137)

Strategies of dose escalation in the treatment of locally advanced non-small cell lung cancer: image guidance and beyond

Frontiers in Oncology, 2014
Radiation dose in the setting of chemo-radiation for locally advanced non-small cell lung cancer (NSCLC) has been historically limited by the risk of normal tissue toxicity and this has been hypothesized to correlate with the poor results in regard to ...
Alexander eChi, Nam Phong Nguyen, James S Welsh, William eTse, Manish eMonga, Olusola eOduntan, Mohammed eAlmubarak, John eRogers, Scot C Remick, David eGius   +9 more
doaj   +1 more source

Evaluation of Robustness to Setup and Range Uncertainties for Head and Neck Patients Treated With Pencil Beam Scanning Proton Therapy. [PDF]

, 2016
PURPOSE To evaluate the robustness of head and neck plans for treatment with intensity modulated proton therapy to range and setup errors, and to establish robustness parameters for the planning of future head and neck treatments.
Lomax, Antony J, Weber, Damien Charles, Malyapa, Robert, Albertini, Francesca, Lowe, Matthew, Bolsi, Alessandra, Malyapa, Robert (author), Weber DC, Albertini, Francesca (author), Lomax, Antony J. (author), Bolsi, A, Albertini, F, Bolsi, Alessandra (author), Malyapa R, Albertini F, Lowe, Matthew (author), Lomax AJ, Weber, D, Lomax, A, Weber, Damien C. (author), Lowe M, Bolsi A, Malyapa, R   +22 more
core   +1 more source

Reduction of organ of interest dose in proton therapy for oesophageal cancer through optimized setup robustness settings and online adaptation

Physics and Imaging in Radiation Oncology
Background and purpose: Oesophageal radiotherapy may cause side effects due to high organs of interest (OOIs) doses. While proton therapy (PT) reduces OOI dose compared to photon therapy, setup robustness settings used may limit OOI sparing.
Eva van Weerd, Anne Lisa Wolf, Steven J.M. Habraken, Yvonne L.B. Klaver, Mischa S. Hoogeman   +4 more
doaj   +1 more source

Merging proton radiographies with treatment planning CT for adaptive radiation therapy [PDF]

, 2016
Ion CT imaging (iCT), as obtained from tomographic reconstruction of ion radiographies, can be considered an emerging modality for adaptive radiation therapy (ART) in ion beam therapy due to accurate characterization of the in-room/in-beam anatomy in ...
Gianoli, Chiara, Ganswindt, Ute, Landry, Guillaume, Meyer, Sebastian, Parodi, Katia, Thieke, Christian, Dedes, George, Magallanes, Lorena, Nijhuis, Reinoud, Belka, Claus   +9 more
core   +1 more source

Robust optimization considering uncertainties in adaptive proton therapy.

Proton therapy, a promising alternative to conventional photon therapy, has gained widespread acceptance in clinical practice. This is attributed to its superior depth-dose curve that has a negligible dose beyond the maximum range of the proton. A proton
Kaushik, Suryakant
core   +2 more sources

Modifying Adaptive Therapy to Enhance Competitive Suppression

, 2020
Adaptive therapy is a promising new approach to cancer treatment. It is designed to leverage competition between drug-sensitive and drug-resistant cells in order to suppress resistance and maintain tumor control for longer.
Elsa Hansen, Andrew F. Read
core   +1 more source

Unsupervised Deep Learning for Synthetic CT Generation from CBCT Images for Proton and Carbon Ion Therapy for Paediatric Patients

Sensors
Image-guided treatment adaptation is a game changer in oncological particle therapy (PT), especially for younger patients. The purpose of this study is to present a cycle generative adversarial network (CycleGAN)-based method for synthetic computed ...
Matteo Pepa, Siavash Taleghani, Giulia Sellaro, Alfredo Mirandola, Francesca Colombo, Sabina Vennarini, Mario Ciocca, Chiara Paganelli, Ester Orlandi, Guido Baroni, Andrea Pella   +10 more
doaj   +1 more source

Triggered plan adaptation using multi-image optimization for improved robustness in head-and-neck cancer proton therapy

Physics and Imaging in Radiation Oncology
Background and purpose: Anatomical variations in head-and-neck (HNC) proton therapy may degrade target coverage and organ-at-risk (OAR) sparing.
Nadine Vatterodt, Brian Winey, Stine S. Korreman   +2 more
doaj   +1 more source

A critical appraisal of the clinical utility of proton therapy in oncology

, 2015
Dongxu WangDepartment of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA, USAAbstract: Proton therapy is an emerging technology for providing radiation therapy to cancer patients.
Wang D
core  

Insights from initial experience for nasopharyngeal carcinoma patients treated with proton therapy

Technical Innovations & Patient Support in Radiation Oncology
Radiotherapy is the cornerstone for the treatment of nasopharyngeal carcinoma (NPC). Due to its unique epidemiology and the location of the disease with neighbouring critical structures, conventional photon irradiation may result in significant long-term
S.Y. Sin, S.N. Chen, Y.L. Soong, H.Q. Tan   +3 more
doaj   +1 more source