Results 91 to 100 of about 4,471,539 (245)

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

Food Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima, István Dalmadi, Anna Jánosi, Krisztina Takács, Eszter Halmy   +4 more
wiley   +1 more source

Role of Endothelial Cell Lipoprotein Lipase for Brown Adipose Tissue Lipid and Glucose Handling

Frontiers in Physiology, 2022
Cold-induced activation of brown adipose tissue (BAT) has an important impact on systemic lipoprotein metabolism by accelerating the processing of circulating triglyceride-rich lipoproteins (TRL).
Ellen Thiemann, Gerburg K. Schwaerzer, Ioannis Evangelakos, Marceline M. Fuh, Michelle Y. Jaeckstein, Janina Behrens, Stefan K. Nilsson, Manju Kumari, Manju Kumari, Ludger Scheja, Alexander Pfeifer, Joerg Heeren, Markus Heine   +12 more
doaj   +1 more source

Nardilysin in adipocytes regulates UCP1 expression and body temperature homeostasis

Scientific Reports, 2022
Brown adipose tissue (BAT) dissipates chemical energy as heat through uncoupling protein 1 (UCP1). The induction of mitochondrial reactive oxygen species (ROS) in BAT was recently identified as a mechanism that supports UCP1-dependent thermogenesis.
Sayaka Saijo, Mikiko Ohno, Hirotaka Iwasaki, Shintaro Matsuda, Kiyoto Nishi, Yoshinori Hiraoka, Natsuki Ide, Takeshi Kimura, Eiichiro Nishi   +8 more
doaj   +1 more source

Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling

, 2018
Excess caloric intake results in increased fat accumulation and an increase in energy expenditure via diet-induced adaptive thermogenesis; however, the underlying mechanisms controlling these processes are unclear.
Low, Jac Kee, Baldock, Paul A., Ip, Chikin, Reed, Felicia, Enriquez, Ronaldo, Lee, Nicola J., Qi, Yue, Karl, Tim (R18316), Herzog, Herbert, Zhang, Lei, Lee, I-Chieh J.   +10 more
core   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

TRPV1 Activation Antagonizes High-Fat Diet-Induced Obesity at Thermoneutrality and Enhances UCP-1 Transcription via PRDM-16

Pharmaceuticals
Body weight is a balance between energy intake and energy expenditure. Energy expenditure is mainly governed by physical activity and adaptive thermogenesis.
Padmamalini Baskaran, Noah Gustafson, Nicolas Chavez   +2 more
doaj   +1 more source

The role of appetite-related hormones, adaptive thermogenesis, perceived hunger and stress in long-term weight-loss maintenance: a mixed-methods study

European Journal of Clinical Nutrition, 2020
Background/objectives Weight-loss maintenance is challenging, and few succeed in the long term. This study aimed to explain how appetite-related hormones, adaptive thermogenesis, perceived hunger and stress influence weight-loss maintenance.
G. Thom, S. Dombrowski, Naomi Brosnahan, Y. Y. Algindan, M. R. Lopez-gonzalez, G. Roditi, M. Lean, D. Malkova   +7 more
semanticscholar   +1 more source

Molecular Adaptations to Extreme Thermogenesis in Mammalian Hibernators [PDF]

Biophysical Journal, 2014
Thirteen-lined ground squirrels (Ictidomys tridecemlineatus) are obligate mammalian hibernators that make the transition from deep torpor- where body temperatures can be as low as 2°C- to the fully active state within as little as two hours. During arousal from hibernation, squirrels undergo an extreme thermogenesis phase, where core body temperatures ...
Laursen, Willem J., Funk, Owen, Goodman, Jena, Merriman, Dana K., Ingolia, Nicholas T., Bagriantsev, Sviatoslav N., Gracheva, Elena O.   +6 more
openaire   +1 more source

Advantages of low‐glycaemic‐index carbohydrates in regulating glycaemic response of energy bar: A review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Energy bars are widely consumed functional foods among athletes and physically active consumers who require convenient sources of sustained energy. Their carbohydrate composition, particularly the type and ratio of digestible sugars such as glucose, fructose and sucrose, strongly influences glycaemic index (GI), postprandial blood glucose ...
Raju Sasikumar, Ayush Gupta, Selva Kumar T, Kaviarasu Ganesan, Sheena Haorongbam, Ravikumar Rajarathinam, Sandeep Janghu, Sandeep Kumar Panda, Amit K. Jaiswal   +8 more
wiley   +1 more source

Loss of C3a and C5a receptors promotes adipocyte browning and attenuates diet-induced obesity via activating inosine/A2aR pathway

Cell Reports, 2023
Summary: Complement activation is thought to underline the pathologic progression of obesity-related metabolic disorders; however, its role in adaptive thermogenesis has scarcely been explored.
Ling-Ran Kong, Xiao-Hui Chen, Qing Sun, Kai-Yuan Zhang, Lian Xu, Liliqiang Ding, Yan-Ping Zhou, Ze-Bei Zhang, Jing-Rong Lin, Ping-Jin Gao   +9 more
doaj   +1 more source