Results 71 to 80 of about 4,471,539 (245)

A subpopulation of Bdnf-e1–expressing glutamatergic neurons in the lateral hypothalamus critical for thermogenesis control

open access: yesMolecular Metabolism, 2020
Objective: Brown adipose tissue (BAT)–mediated thermogenesis plays a key role in energy homeostasis and the maintenance of body temperature. Previous work suggests that brain-derived neurotrophic factor (BDNF) is involved in BAT thermogenesis, but the ...
He You, Pengcheng Chu, Wei Guo, Bai Lu
doaj   +1 more source

Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice

open access: yesNature Communications, 2023
Brown adipose tissue (BAT) has abundant mitochondria with the unique capability of generating heat via uncoupled respiration. Mitochondrial uncoupling protein 1 (UCP1) is activated in BAT during cold stress and dissipates mitochondrial proton motive ...
Anna Park   +22 more
doaj   +1 more source

Chronic cold exposure induces autophagy to promote fatty acid oxidation, mitochondrial turnover, and thermogenesis in brown adipose tissue

open access: yesiScience, 2021
Summary: Autophagy plays an important role in lipid breakdown, mitochondrial turnover, and mitochondrial function during brown adipose tissue (BAT) activation by thyroid hormone, but its role in BAT during adaptive thermogenesis remains controversial ...
Winifred W. Yau   +7 more
doaj   +1 more source

Floral thermogenesis: An adaptive strategy of pollination biology in Magnoliaceae [PDF]

open access: yesCommunicative & Integrative Biology, 2015
Floral thermogenesis plays a crucial role in pollination biology, especially in plant-pollinator interactions. We have recently explored how thermogenesis is related to pollinator activity and odour release in Magnolia sprengeri. By analyzing flower temperatures, emission of volatiles, and insect visitation, we found that floral blends released during ...
Wang, Ruohan, Zhang, Zhixiang
openaire   +2 more sources

Mitochondrial proton conductance in skeletal muscle of a cold-exposed marsupial, Antechinus flavipes, is unlikely to be involved in adaptive non-shivering thermogenesis but displays increased sensitivity towards carbon-centered radicals [PDF]

open access: yes, 2009
The organs and molecular mechanisms contributing to adaptive thermogenesis in marsupials are not known because some species apparently lack brown adipose tissue (BAT).
Withers, Kerry   +3 more
core   +1 more source

Prion‐Like Protein LENG8‐Mediated Nucleation Drives Stress Granule Assembly

open access: yesAdvanced Science, EarlyView.
LENG8 is a newly identified stress granule (SG) nucleator required for SG assembly. Following stress, nuclear LENG8 granules disassemble, allowing LENG8 to translocate into the cytoplasm and form independent nucleation foci. These foci fuse with canonical early G3BP1/TIA1 seeds via LENG8‐TIA1 binding to drive SG maturation.
Mingxing Zhang   +6 more
wiley   +1 more source

Recent advances in adaptive thermogenesis: potential implications for the treatment of obesity. [PDF]

open access: yes, 2009
Summary Large inter-individual differences in cold-induced (non-shivering) and diet-induced adaptive thermogenesis exist in animals and humans. These differences in energy expenditure can have a large impact on long-term energy balance and thus body ...
van Marken Lichtenbelt, W.   +5 more
core   +2 more sources

Effects of intermittent exposure to hypobaria and cold on the microarchitecture and morphofunctional profile of rat gastrocnemius muscle

open access: yesThe Anatomical Record, EarlyView.
Abstract Intermittent hypobaric hypoxia (IHH) enhances oxygen transport, muscle metabolism, and cardiovascular health; however, the combined effects of hypobaria and cold are less well understood. Exposure to these stressful environmental factors, even intermittently, can affect skeletal muscle due to its plasticity, thereby altering its metabolic and ...
Garoa Santocildes   +3 more
wiley   +1 more source

Evaluation of Thermogenesis in Cold-Acclimated and Exercise-Trained Rats [PDF]

open access: yes, 1990
This study was designed to evaluated the resting thermogenesis in cold-acclimated and exercisetrained rats,c onsidering the body composition. This total metabolic rate and lean body mass for the sedentary warm acclimated group were similar to those for ...
上田, 五雨   +3 more
core  

Is thermogenesis really needed for brown adipose tissue–mediated metabolic benefit?

open access: yesThe Journal of Clinical Investigation, 2022
Brown adipose tissue (BAT) dissipates energy in the form of heat and functions as a metabolic sink for lipids, glucose, and branched-chain amino acids. Enhanced BAT thermogenesis is thought to tightly couple with beneficial energy metabolism. However, in
Jin-Seon Yook, Shingo Kajimura
doaj   +1 more source

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