Results 231 to 240 of about 33,952 (267)

Faculty Opinions recommendation of The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2002
openaire   +2 more sources

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

KANK1 regulates the positioning of liprin-α1 and the spatial organization of insulin granule fusion in pancreatic β cells. [PDF]

J Biol Chem
Deng K, Sun K, Webster H, Yau B, Loudovaris T, Thomas HE, Kebede MA, Thorn P.   +7 more
europepmc   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

Proteome profiling indicates a link between mitochondrial pathways and the host-microbial sensor ELMO1 following <i>Salmonella</i> infection. [PDF]

Gut Microbes
Achi SC, McGrosso D, Tocci S, Amao I, Saha B, Ibeawuchi SR, Sayed IM, Gonzalez DJ, Das S.   +8 more
europepmc   +1 more source

Evaluation of Pathogenic Variants Associated With Monogenic Disorders of Dyslipidemia in Patients With Well Characterised MASLD. [PDF]

Liver Int
Schwantes-An TH, Abreu MA, Neuschwander-Tetri BA, Wang J, Guo X, Tan J, Hegele RA, Davidson NO, Lotta L, Verweij N, Yates KP, Rotter JI, Chalasani N.   +12 more
europepmc   +1 more source

The Role of Prion Protein in Reelin/Dab1 Signaling: Implications for Neurodegeneration. [PDF]

Viruses
Rolle IG, Burato A, Bacınoğlu MB, Moda F, Legname G.   +4 more
europepmc   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation. [PDF]

FEBS Lett
Snelling T, Hunter K, Tay CWS, Wood NT, Cohen P.   +4 more
europepmc   +1 more source

Discovery of a Proteolysis Targeting Chimera for TRKA and RET-derived oncoproteins. [PDF]

Sci Rep
Moccia M, Zhang L, Wang Z, Wang M, Federico G, Santoro M, Li HY, Carlomagno F.   +7 more
europepmc   +1 more source

UBQLN2 in neurodegenerative disease: mechanistic insights and emerging therapeutic potential. [PDF]

Biochem Soc Trans
Matthews AM, Whiteley AM.
europepmc   +1 more source