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Signal-transducing adaptor protein-2 regulates macrophage migration into inflammatory sites during dextran sodium sulfate induced colitis

Signal-transducing adaptor protein-2 regulates macrophage migration into inflammatory sites during dextran sodium sulfate induced colitis
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Graft-versus-host disease develops in mice transplanted with lymphocyte-depleted bone marrow cells from signal-transducing adaptor protein-2 transgenic mice

Graft-versus-host disease develops in mice transplanted with lymphocyte-depleted bone marrow cells from signal-transducing adaptor protein-2 transgenic mice
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Graft-versus-host disease develops in mice transplanted with lymphocyte-depleted bone marrow cells from signal-transducing adaptor protein-2 transgenic mice

Biochemical and Biophysical Research Communications, 2021
Graft-versus-host disease (GVHD) is the most frequent complication after allogeneic hematopoietic stem cell transplantation (HSCT), and is one of the major causes of non-relapse mortality. Transferred mature lymphocytes are thought to be responsible for GVHD based on the findings that mice transplanted with lymphocyte-depleted bone marrow (BM) cells ...
Hideaki Saito, Michiko Ichii, Jun Toda, Yuichi Kitai, Ryuta Muromoto, Jun-ichi Kashiwakura, Kodai Saitoh, Akira Tanimura, Takafumi Yokota, Hirohiko Shibayama, Tadashi Matsuda, Kenji Oritani, Yuzuru Kanakura, Naoki Hosen   +13 more
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Signal‐transducing adaptor protein‐2 regulates macrophage migration into inflammatory sites during dextran sodium sulfate induced colitis

European Journal of Immunology, 2014
Signal‐transducing adaptor protein‐2 (STAP‐2) was cloned as a c‐fms/M‐CSF receptor interacting protein. STAP‐2 is an adaptor protein carrying pleckstrin homology and Src homology 2 like domains, as well as a YXXQ motif. STAP‐2 has been indicated to have an ability to bind and modulate a variety of signaling and transcriptional molecules.
Natsuko, Fujita, Kenji, Oritani, Michiko, Ichii, Takafumi, Yokota, Norimitsu, Saitoh, Daisuke, Okuzaki, Yuichi, Sekine, Shigeyuki, Kon, Ryuta, Muromoto, Kodai, Saitoh, Akihiko, Yoshimura, Tadashi, Matsuda, Yuzuru, Kanakura   +12 more
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Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation

The Journal of Immunology
Abstract Signal-transducing adaptor protein (STAP)-1 is an adaptor protein that is widely expressed in T cells. In this article, we show that STAP-1 upregulates TCR-mediated T cell activation and T cell–mediated airway inflammation. Using STAP-1 knockout mice and STAP-1–overexpressing Jurkat cells, we found that STAP-1 enhanced TCR ...
Kota Kagohashi, Yuto Sasaki, Kiyotaka Ozawa, Takuya Tsuchiya, Shoya Kawahara, Kodai Saitoh, Michiko Ichii, Jun Toda, Yasuyo Harada, Masato Kubo, Yuichi Kitai, Ryuta Muromoto, Kenji Oritani, Jun-ichi Kashiwakura, Tadashi Matsuda   +14 more
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Signal-Transducing Adaptor Protein 1

2020
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SignalP 6.0 predicts all five types of signal peptides using protein language models

Nature Biotechnology, 2022
Felix Teufel, Jose Juan Almagro Armenteros, Alexander Rosenberg Johansen   +2 more
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Advances in Prostate Cancer Chemotherapy: A New Era Begins

Ca-A Cancer Journal for Clinicians, 2005
Kenneth J Pienta, David C Smith
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Signal integration in the endoplasmic reticulum unfolded protein response

Nature Reviews Molecular Cell Biology, 2007
David Ron, Peter Walter
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The myriad roles of cyclic AMP in microbial pathogens: from signal to sword

Nature Reviews Microbiology, 2011
Kathleen A Mcdonough
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