Results 111 to 120 of about 40,794 (233)
Current progress of digital twin construction using medical imaging
Journal of Applied Clinical Medical Physics, Volume 26, Issue 9, September 2025.Abstract Medical imaging is fundamental to digital twin technology, enabling patient‐specific virtual models of anatomy and physiology. By integrating high‐resolution modalities (Magnetic Resonance Imaging (MRI), Computed Tomography (CT), Positron Emission Tomography (PET), ultrasound) with computational frameworks, recent imaging advances now support ...
Feng Zhao +6 more
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 197, Issue 9, September 2025.ABSTRACT Genitopatellar syndrome (GPS) and Say‐Barber‐Biesecker‐Young‐Simpson Syndrome (SBBYSS) are clinically distinct neurodevelopmental disorders caused by monoallelic pathogenic variants in KAT6B. In some cases, GPS and SBBYSS features can overlap, determining an intermediate phenotype.
Vittorio Maglione +12 more
wiley +1 more source
Phylogenetic and structural analysis of Hydra ADAR
Archives of Biochemistry and BiophysicsAdenosine deaminases acting on RNAs (ADARs) perform adenosine-to-inosine (A-to-I) RNA editing for essential biological functions. While studies of editing sites in diverse animals have revealed unique biological roles of ADAR editing including temperature adaptation and reproductive maturation, rigorous biochemical and structural studies of these ADARs
Xander E. Wilcox +8 more
openaire +3 more sources
The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis
eLife, 2017 ADAR proteins alter gene expression both by catalyzing adenosine (A) to inosine (I) RNA editing and binding to regulatory elements in target RNAs. Loss of ADARs affects neuronal function in all animals studied to date.
Sarah N Deffit +9 more
doaj +1 more source
ADAR promotes USP38 auto-deubiquitylation and stabilization in an RNA editing-independent manner in esophageal squamous cell carcinoma. [PDF]
J Biol ChemHu Q +7 more
europepmc +2 more sources
Environmetrics, Volume 36, Issue 6, September 2025.ABSTRACT Epidemiological analyses of environmental risk factors often include spatially varying exposures and outcomes. Unmeasured, spatially varying factors can lead to confounding bias in estimates of associations with adverse health outcomes. Several approaches for mitigating this bias have been developed using semiparametric splines.
Maddie J. Rainey, Kayleigh P. Keller
wiley +1 more source
Intergenerational Transmission: Observed Negative Communication Mediates Dyadic Associations Between Childhood Maltreatment and Marital Quality [PDF]
Fam ProcessABSTRACT Childhood maltreatment (CM), a complex trauma, has long been recognized as a detrimental predictor of marital quality in adulthood. Although research has almost exclusively focused on the associations of CM with a range of relationship outcomes from an individual perspective, the dyadic effects of CM on couple interactions and marital quality ...
Zamir O +5 more
europepmc +2 more sources
Finding Streams in Knowledge Graphs to Support Fact Checking
, 2017 The volume and velocity of information that gets generated online limits current journalistic practices to fact-check claims at the same rate. Computational approaches for fact checking may be the key to help mitigate the risks of massive misinformation ...
Ciampaglia, Giovanni Luca +3 more
core +1 more source
An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation
Cell ReportsSummary: Adar null mutant mouse embryos die with aberrant double-stranded RNA (dsRNA)-driven interferon induction, and Adar Mavs double mutants, in which interferon induction is prevented, die soon after birth.
Ketty Sinigaglia +14 more
doaj +1 more source