Results 101 to 110 of about 42,435 (206)

Link-Prediction Enhanced Consensus Clustering for Complex Networks

, 2015
Many real networks that are inferred or collected from data are incomplete due to missing edges. Missing edges can be inherent to the dataset (Facebook friend links will never be complete) or the result of sampling (one may only have access to a portion ...
Adar, Eytan, Burgess, Matthew, Cafarella, Michael   +2 more
core   +3 more sources

An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation

Cell Reports
Summary: Adar null mutant mouse embryos die with aberrant double-stranded RNA (dsRNA)-driven interferon induction, and Adar Mavs double mutants, in which interferon induction is prevented, die soon after birth.
Ketty Sinigaglia, Anna Cherian, Qiupei Du, Valentina Lacovich, Dragana Vukić, Janka Melicherová, Pavla Linhartova, Lisa Zerad, Stanislav Stejskal, Radek Malik, Jan Prochazka, Nadège Bondurand, Radislav Sedláček, Mary A. O’Connell, Liam P. Keegan   +14 more
doaj   +1 more source

The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis

eLife, 2017
ADAR proteins alter gene expression both by catalyzing adenosine (A) to inosine (I) RNA editing and binding to regulatory elements in target RNAs. Loss of ADARs affects neuronal function in all animals studied to date.
Sarah N Deffit, Brian A Yee, Aidan C Manning, Suba Rajendren, Pranathi Vadlamani, Emily C Wheeler, Alain Domissy, Michael C Washburn, Gene W Yeo, Heather A Hundley   +9 more
doaj   +1 more source

CSR Practice in the Drc's Mining Sector by Chinese Firms [PDF]

, 2010
The author analyses the CSR practice in mining area by Chinese ...
Johanna Jansson
core  

An examination of the relationship between firm size and export activity in the New Zealand lumber industry : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Development Studies, Massey University [PDF]

, 1993
This thesis explores the relationship between export activity and firm size, with specific reference to New Zealands lumber industry. The main purpose of this investigation is to identify firm characteristics which link firm size to export behavior. This
Craw, Michael Curtis
core  

Recurrent encephalopathy with spinal cord involvement: An atypical manifestation of Aicardi–Goutières syndrome

Annals of Indian Academy of Neurology, 2019
Aicardi–Goutières syndrome (AGS) is a rare, genetic inflammatory disease due to mutations in any of the seven genes discovered to date (TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1).
Debopam Samanta, Raghu Ramakrishnaiah
doaj   +1 more source

Evolving Political Accountability in Kenya [PDF]

, 2010
published or submitted for publicationnot peer ...
Jacob Butler
core  

Phylogenetic and structural analysis of Hydra ADAR

Archives of Biochemistry and Biophysics
Adenosine deaminases acting on RNAs (ADARs) perform adenosine-to-inosine (A-to-I) RNA editing for essential biological functions. While studies of editing sites in diverse animals have revealed unique biological roles of ADAR editing including temperature adaptation and reproductive maturation, rigorous biochemical and structural studies of these ADARs
Xander E. Wilcox, Howard Zhang, Jasmine L. Mah, Jack F. Cazet, Sukanya Mozumder, Srinidhi Venkatesh, Celina E. Juliano, Peter A. Beal, Andrew J. Fisher   +8 more
openaire   +3 more sources

Aicardi-Goutières syndrome type 6: report of ADAR variant and clinical outcome after ruxolitinib treatment in the neonatal period

Pediatric Rheumatology Online Journal
Background Aicardi-Goutières Syndrome is a monogenic type 1 interferonopathy with infantile onset, characterized by a variable degree of neurological damage.
Alba Gabaldon-Albero, Carla Martin-Grau, Miguel Marti-Masanet , Alejandro Lopez-Jimenez, Roberto Llorens, Beatriz Beseler-Soto, Sergio Martin-Zamora, Berta Lopez, Inmaculada Calvo, Sara Hernandez-Muela, Monica Rosello, Carmen Orellana, Francisco Martinez   +12 more
doaj   +1 more source

ADARs regulate cuticle collagen expression and promote survival to pathogen infection

BMC Biology
Background In all organisms, the innate immune system defends against pathogens through basal expression of molecules that provide critical barriers to invasion and inducible expression of effectors that combat infection. The adenosine deaminase that act
Alfa Dhakal, Chinnu Salim, Mary Skelly, Yarden Amichan, Ayelet T. Lamm, Heather A. Hundley   +5 more
doaj   +1 more source