Results 81 to 90 of about 14,644 (161)

Abundant A-to-I RNA editing in spermatocytes may suppress transposons to compensate for piRNA downregulation in male germlines

RNA Biology
The germline genome serves as a crucial battleground for transposon expansion, as transposons can increase their copy numbers in offspring when activated within germ cells.
Yuange Duan, Qiuhua Xie, Ling Ma, Qi Cao
doaj   +1 more source

Bilateral striatal necrosis caused by ADAR mutations in two siblings with dystonia and freckles-like skin changes that should be differentiated from Leigh syndrome

Folia Neuropathologica, 2016
Pathogenic molecular variants in the ADAR gene are a known cause of rare diseases, autosomal recessive Aicardi- Goutières syndrome type 6, severe infantile encephalopathy with intracranial calcifications and dominant dyschromatosis symmetrica hereditaria,
Dorota Piekutowska-Abramczuk, Hanna Mierzewska, Monika Bekiesińska-Figatowska, Elżbieta Ciara, Joanna Trubicka, Maciej Pronicki, Dariusz Rokicki, Małgorzata Rydzanicz, Rafał Płoski, Ewa Pronicka   +9 more
doaj   +1 more source

Charting and probing the activity of ADARs in human development and cell-fate specification

Nature Communications
Adenosine deaminases acting on RNA (ADARs) impact diverse cellular processes and pathological conditions, but their functions in early cell-fate specification remain less understood.
Amir Dailamy, Weiqi Lyu, Sami Nourreddine, Michael Tong, Joseph Rainaldi, Daniella McDonald, Rebecca Panwala, Alysson Muotri, Michael S. Breen, Kun Zhang, Prashant Mali   +10 more
doaj   +1 more source

An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation

Cell Reports
Summary: Adar null mutant mouse embryos die with aberrant double-stranded RNA (dsRNA)-driven interferon induction, and Adar Mavs double mutants, in which interferon induction is prevented, die soon after birth.
Ketty Sinigaglia, Anna Cherian, Qiupei Du, Valentina Lacovich, Dragana Vukić, Janka Melicherová, Pavla Linhartova, Lisa Zerad, Stanislav Stejskal, Radek Malik, Jan Prochazka, Nadège Bondurand, Radislav Sedláček, Mary A. O’Connell, Liam P. Keegan   +14 more
doaj   +1 more source

The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis

eLife, 2017
ADAR proteins alter gene expression both by catalyzing adenosine (A) to inosine (I) RNA editing and binding to regulatory elements in target RNAs. Loss of ADARs affects neuronal function in all animals studied to date.
Sarah N Deffit, Brian A Yee, Aidan C Manning, Suba Rajendren, Pranathi Vadlamani, Emily C Wheeler, Alain Domissy, Michael C Washburn, Gene W Yeo, Heather A Hundley   +9 more
doaj   +1 more source

İlköğretim müzik derslerinde Türk Müziği kullanımına yönelik öğretmen görüşlerinin incelenmesi

, 2019
Müzik eğitimi, her döneminde farklı gelişmelere açık kültürel değerlerine önem veren bireylerin ve toplumların yaşantısında önemli bir yere sahiptir.
Adar, Çağhan, Çağhan ADAR
core   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

ADAR-SHAPE Pipeline — Demo Data (STK4 AluSq2, downsampled)

Downsampled (~300k read pairs/file) STK4 AluSq2 amplicon SHAPE/ADAR sequencing FASTQs plus reference sequence and primers — the bundled demo dataset for the adar-shape-pipeline (ShapeMapper population-average profiles + ADAR A-to-G read sorting ...
Laederach, Alain
core   +1 more source

Aicardi-Goutières syndrome type 6: report of ADAR variant and clinical outcome after ruxolitinib treatment in the neonatal period

Pediatric Rheumatology Online Journal
Background Aicardi-Goutières Syndrome is a monogenic type 1 interferonopathy with infantile onset, characterized by a variable degree of neurological damage.
Alba Gabaldon-Albero, Carla Martin-Grau, Miguel Marti-Masanet , Alejandro Lopez-Jimenez, Roberto Llorens, Beatriz Beseler-Soto, Sergio Martin-Zamora, Berta Lopez, Inmaculada Calvo, Sara Hernandez-Muela, Monica Rosello, Carmen Orellana, Francisco Martinez   +12 more
doaj   +1 more source

Adar Eisenbruch's Quick Files

, 2019
The Quick Files feature was discontinued and it’s files were migrated into this Project on March 11, 2022. The file URL’s will still resolve properly, and the Quick Files logs are available in the Project’s Recent ...
Adar Eisenbruch
core   +1 more source