Results 71 to 80 of about 42,435 (206)
ABSTRACT Aim To explore changes in body composition in adolescents with obesity treated with glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA) and their association with metabolic syndrome (MetS) components. Methods This real‐world retrospective study included adolescents (12–18 years) with obesity who received multidisciplinary lifestyle‐based ...
Adar Lopez +11 more
wiley +1 more source
ADARs: Viruses and Innate Immunity [PDF]
Double-stranded RNA (dsRNA) functions both as a substrate of ADARs and also as a molecular trigger of innate immune responses. ADARs, adenosine deaminases that act on RNA, catalyze the deamination of adenosine (A) to produce inosine (I) in dsRNA. ADARs thereby can destablize RNA structures, because the generated I:U mismatch pairs are less stable than ...
openaire +2 more sources
Post‐transcriptional regulatory networks: The dynamic interplay of RNA‐binding proteins
Post‐transcriptional gene expression regulation is controlled by RNA‐binding proteins (RBPs), which influence many processes including splicing, localization, translation, and decay. Rather than acting alone, RBPs bind RNAs combinatorially, forming complex, context‐dependent regulatory networks.
Lena A. Street +2 more
wiley +1 more source
Coauthor prediction for junior researchers [PDF]
Research collaboration can bring in different perspectives and generate more productive results. However, finding an appropriate collaborator can be difficult due to the lacking of sufficient information.
Brusilovsky, P, Han, S, He, D, Yue, Z
core +1 more source
ABSTRACT From its very inception, the Jewish National Movement Hibbat Zion turned to the collective past to advance its goals in the present. One of their activities was to reinterpret Jewish holidays and festivals, especially those that did not take a central place in the Jewish calendar.
Asaf Yedidya
wiley +1 more source
Therapeutic targeting of the adenosine deaminase ADAR has great potential in cancer and other indications; however, it remains unclear what approach can enable effective and selective therapeutic inhibition.
Benjamin G Gowen +12 more
doaj +1 more source
Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang +7 more
wiley +1 more source
ABSTRACT This study examined the developmental processes of paracrises and reputational threats amplified on social media, through a case study of the Adidas SL72 sneaker campaign, a faux pas‐type paracrisis. Unlike crises that directly threaten organizational survival, paracrises are reputational threats that primarily impact corporate social ...
Da Eun Song, Dan Ro, Hyunmi Baek
wiley +1 more source
How do ADARs bind RNA? New protein‐RNA structures illuminate substrate recognition by the RNA editing ADARs [PDF]
Deamination of adenosine in RNA to form inosine has wide ranging consequences on RNA function including amino acid substitution to give proteins not encoded in the genome. What determines which adenosines in an mRNA are subject to this modification reaction?
Thomas, Justin M, Beal, Peter A
openaire +4 more sources
Improved arrayed-waveguide-grating layout avoiding systematic phase errors [PDF]
We present a detailed description of an improved arrayed-waveguide-grating (AWG) layout for both, low and high diffraction orders. The novel layout presents identical bends across the entire array; in this way systematic phase errors arising from ...
Driessen, Alfred +6 more
core +4 more sources

