Results 61 to 70 of about 8,523 (174)

Epigenetic‐Based Evidence for Distinct Effects of Age, Sex, and Experience in Developmental Critical Period Learning

open access: yesDevelopmental Neurobiology, Volume 86, Issue 3, July 2026.
ABSTRACT Although much is known about the encoding of experience, how the brain organizes neural circuits capable of learning and memory formation is largely unstudied. Canonical critical periods emerge from a convergence of maturation‐ and experience‐dependent processes.
Grant W. Kunzelman   +2 more
wiley   +1 more source

miRNA Sensor HuR Compartmentalizes Ago2‐Uncoupled miRNAs to Lipid Droplets to Buffer miRNA Activity in Mammalian Cells

open access: yesThe FASEB Journal, Volume 40, Issue 11, 15 June 2026.
This study revealed a dose‐dependent miRNA buffering mechanism involving extracellular export and storage of miRNA on lipid droplets. The protein HuR facilitates miRNA buffering by dissociating miRNAs from Ago2 and promoting miRNA accumulation on lipid droplets or its extracellular export, depending on cellular requirements.
Sreemoyee Chakraborty   +3 more
wiley   +1 more source

Challenging the prokaryotic MGE‐defense origin of eukaryotic RNA editing

open access: yes
mLife, EarlyView.
Yuange Duan   +4 more
wiley   +1 more source

Urban greenspace and dementia: Measures, mechanisms, and methodological guidance

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Urban greenspace has been associated with improved cognition and reduced Alzheimer's disease (AD) and AD‐related dementias (ADRD) risk, but findings remain mixed, study quality varies, and evidence is largely cross‐sectional. To advance the field, we offer guidance to select and apply greenspace exposure measures in AD/ADRD research.
Ingrid Jarvis   +15 more
wiley   +1 more source

Utilizing AAV-mediated LEAPER 2.0 for programmable RNA editing in non-human primates and nonsense mutation correction in humanized Hurler syndrome mice

open access: yesGenome Biology, 2023
Background The endogenous adenosine deaminases acting on RNA (ADAR) have been harnessed to facilitate precise adenosine-to-inosine editing on RNAs.
Zongyi Yi   +15 more
doaj   +1 more source

Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang   +7 more
wiley   +1 more source

Link Prediction with Swarms of Chiral Quantum Walks

open access: yesAdvanced Quantum Technologies, Volume 9, Issue 6, June 2026.
Network reconstruction is a fundamental problem in network biology. We propose a link prediction method based on a swarm of chiral quantum walks. Random phase assignments in each walker's Hamiltonian generator produce complementary dynamics on the same topology.
Gaia Forghieri   +3 more
wiley   +1 more source

Narratives, Networks, and the Evolution of Paracrises: Evidence From X (Twitter) Discourse on the Adidas SL72 Campaign

open access: yesJournal of Contingencies and Crisis Management, Volume 34, Issue 2, June 2026.
ABSTRACT This study examined the developmental processes of paracrises and reputational threats amplified on social media, through a case study of the Adidas SL72 sneaker campaign, a faux pas‐type paracrisis. Unlike crises that directly threaten organizational survival, paracrises are reputational threats that primarily impact corporate social ...
Da Eun Song, Dan Ro, Hyunmi Baek
wiley   +1 more source

Reliance as Promise

open access: yesAmerican Business Law Journal, Volume 63, Issue 2, Page 105-127, Summer 2026.
Abstract In the face of powerful criticism, the “reliance interest” continues to hold an impactful position in judicial and academic treatment of contract damages. And yet, the theoretical foundation of reliance damages for breach of contract remains unsettled.
Yehuda Adar, Efi Zemach
wiley   +1 more source

Expressional Localization and Functionally Identifying an RNA Editing Enzyme BmADARa of the Silkworm Bombyx mori

open access: yesInsects, 2020
The most common type of RNA editing in metazoans is the deamination of adenosine into inosine (A-to-I) catalyzed by the adenosine deaminase acting on the RNA (ADAR) family of proteins.
Chongjun Ye   +6 more
doaj   +1 more source

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