Results 111 to 120 of about 42,435 (206)

Featured Cover [PDF]

open access: yesAging Cell
Cover legend: The cover image is based on the article Plasma Proteome Profiling of Centenarian Across Switzerland Reveals Key Youth‐Associated Proteins by Flavien Delhaes et al., https://doi.org/10.1111/acel.70409.
Flavien Delhaes   +8 more
europepmc   +2 more sources

The role of distinct APOBEC/ADAR mRNA levels in mutational signatures linked to aging and ultraviolet radiation

open access: yesScientific Reports
The APOBEC/AID family is known for its mutator activity, and recent evidence also supports the potential impact of ADARs. Furthermore, the mutator impacts of APOBEC/ADAR mutations have not yet been investigated.
Ahmadreza Niavarani
doaj   +1 more source

Adare Manor: Tasting Menu [PDF]

open access: yes, 2013
Adare Manor is a five star hotel and golf resort located in the picturesque village of Adare in Co. Limerick. The house is set on a 840-acre (3.4 km2) estate and now operates as a five star hotel, featuring the Adare Golf Club, Lavender Cottage, Townhouses and Villas on the rest of the resort.
openaire  

An engineered U7 small nuclear RNA scaffold greatly increases ADAR-mediated programmable RNA base editing

open access: yesNature Communications
Custom RNA base editing exploiting the human Adenosine Deaminase Acting on RNA (ADAR) enzyme may enable therapeutic gene editing without DNA damage or use of foreign proteins.
Susan M. Byrne   +10 more
doaj   +1 more source

RNA editing deficiency models differential immunogenicity of pancreatic α- and β-cells

open access: yesMolecular Metabolism
Objective: A longstanding question in type 1 diabetes (T1D) research pertains to the selective loss of β-cells whilst neighboring islet α-cells remain unharmed.
Shani Peleg   +12 more
doaj   +1 more source

Adare 1826 Restaurant Menu 2020

open access: yes, 2020
As Limerick's reputation for good food continues to grow, the chef who brought his skill to the area, Wade Murphy, continues to do what he does best in this lovely roadside restaurant. The roof may be thatched but the methods are very much today, and Murphy is fanatical about local incredients and a great ambassador for Irish food.
openaire   +1 more source

ADAR Proteins in Human Diseases

open access: yes, 2020
Adenosine deaminase acting on RNA (ADAR) is a mammalian protein family, consisting of five enzymes out of which ADAR1 and ADAR2 possess catalytic activity. Their mechanism of action, called A-to-I (adenosine-to-inosine) editing, is a post-transcriptional modification on double-stranded RNA (dsRNA) molecules and occurs in both nucleus and cytoplasm of ...
openaire   +1 more source

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