Results 131 to 140 of about 43,703 (264)

ADAR-deficiency perturbs the global splicing landscape in mouse tissues

open access: yesGenome Research, 2020
Adenosine-to-inosine RNA editing and pre-mRNA splicing largely occur cotranscriptionally and influence each other. Here, we use mice deficient in either one of the two editing enzymes ADAR (ADAR1) or ADARB1 (ADAR2) to determine the transcriptome-wide ...
Utkarsh Kapoor   +6 more
semanticscholar   +1 more source

Recent Developments and Emerging Challenges in Tracer‐Aided Modeling

open access: yesWIREs Water, Volume 12, Issue 2, March/April 2025.
Together with more intensive tracer monitoring, tracer‐aided models (TAMs) have evolved into more sophisticated tools and expanded their range of potential applications, while their limitations persist and have become more apparent. ABSTRACT During the last decade, tracer‐aided hydrological models (TAMs) have been applied in numerous studies and have ...
Hyekyeng Jung   +3 more
wiley   +1 more source

Recurrent encephalopathy with spinal cord involvement: An atypical manifestation of Aicardi–Goutières syndrome

open access: yesAnnals of Indian Academy of Neurology, 2019
Aicardi–Goutières syndrome (AGS) is a rare, genetic inflammatory disease due to mutations in any of the seven genes discovered to date (TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1).
Debopam Samanta, Raghu Ramakrishnaiah
doaj   +1 more source

AEGIS Data Analysis and Reduction (ADAR) in Support of the AEGIS Weapon System (AWS) [PDF]

open access: yes, 1998
The AEGIS Weapons System (AWS), part of the AEGIS Combat System (ACS), is an integral part of the defense system on U.S. Navy AEGIS-class ships. AEGIS Data Analysis and Reduction (ADAR) has been developed to assist in the evaluation of the AWS data. ADAR,
Gaines, June Bullard
core   +1 more source

Advances in Detection Methods for A‐to‐I RNA Editing

open access: yesWIREs RNA, Volume 16, Issue 2, March/April 2025.
Caption: Early identification of A‐to‐I RNA editing sites was achieved through Sanger sequencing, with the introduction of next‐generation sequencing (NGS) enabling transcriptome‐wide analyses. In recent years, detection approaches have expanded beyond sequencing‐based strategies to include chemically assisted and enzyme‐assisted methods, which offer ...
Yuxi Yang, Masayuki Sakurai
wiley   +1 more source

REPAIR - new tool for RNA editing with Cas13 [PDF]

open access: yes, 2018
Istraživači su nedavno razvili alat REPAIR koji se sastoji od spojene katalitičke domene deaminaze ADAR i katalitički mrtvog Cas13b, iz obitelji proteina Cas13.
Majsec, Petra
core   +2 more sources

Discriminative Link Prediction using Local Links, Node Features and Community Structure

open access: yes, 2013
A link prediction (LP) algorithm is given a graph, and has to rank, for each node, other nodes that are candidates for new linkage. LP is strongly motivated by social search and recommendation applications. LP techniques often focus on global properties (
Chakrabarti, Soumen   +2 more
core   +1 more source

QCD3 dualities and the F-theorem

open access: yesJournal of High Energy Physics, 2018
There has recently been a surge of new ideas and results for 2+1 dimensional gauge theories. We consider a recently proposed duality for 2+1 dimensional QCD, which predicts a symmetry-breaking phase.
Adar Sharon
doaj   +1 more source

Leveraging Endogenous ADAR for Programmable Editing on RNA [PDF]

open access: yes, 2019
AbstractNucleic acid editing carries enormous potential for biological research and the development of therapeutics. Current tools for DNA or RNA editing rely on introducing exogenous proteins into living organisms, which is subject to potential risks or technical barriers due to possible aberrant effector activity, delivery limits and immunogenicity ...
Feng Tian   +13 more
openaire   +2 more sources

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