Results 151 to 160 of about 26,161 (209)

Predictive value of natural killer (NK) cells in bone marrow for relapse in diffuse large B cell lymphoma: integrating antibody-dependent cell-mediated cytotoxicity (ADCC)-based immunotherapy. [PDF]

Cancer Immunol Immunother
Rincón-López S, Atencio-Matos J, Pereda-Sainz O, Larreina-Pérez J, Campeny-Najara A, Esteban-Figuerola A, Hernandez-Perez M, Garrastachu-Zumaran P, Velasco-Ruiz M, García-Bosque I, Rodriguez-Lefler C, Ruiz de Gaona E, Feliu J, Cabello J, Martín-Carnicero A, García-Muñoz R.   +15 more
europepmc   +1 more source

Precision Fc remodeling via glycosylation-competent CHO display enables ultra-selective FcγRIIIa targeting and enhanced antitumor activity. [PDF]

J Biol Eng
Jo M, Kim S, Ko S, Kyung M, Lee S, Ko WH, Lee W, Jung ST.   +7 more
europepmc   +1 more source

AdcBC-dependent zinc uptake influences physiological responses in <i>Streptococcus mutans</i>. [PDF]

J Oral Microbiol
Pedrosa MDS, Schuls CS, Iannaccone LL, Ribeiro AA.   +3 more
europepmc   +1 more source

High levels of circulating miR-19a-3p in patients with metastatic HER2 + breast cancer are associated with a favorable prognosis and anti-tumor immune responses. [PDF]

Breast Cancer Res
Cohen EN, Gao H, Tin S, Wu Q, Ivan C, Ueno NT, Woodward WA, Reuben JM, Anfossi S.   +8 more
europepmc   +1 more source

マクロファージ介在ADCC

マクロファージ介在ADCC
openaire  

Development of a Macrophage-Based ADCC Assay [PDF]

Vaccines, 2021
Fc-dependent effector functions are an important determinant of the in vivo potency of therapeutic antibodies. Effector function is determined by the combination of FcRs bound by the antibody and the cell expressing the relevant FcRs, leading to antibody-dependent cellular cytotoxicity (ADCC).
Fahmida Alam, Sean T H Liu, Adolfo Garcia-Sastre   +2 more
exaly   +4 more sources

Combination Strategies to Enhance Antitumor ADCC [PDF]

Immunotherapy, 2012
The clinical efficacy of monoclonal antibodies as cancer therapeutics is largely dependent upon their ability to target the tumor and induce a functional antitumor immune response. This two-step process of ADCC utilizes the response of innate immune cells to provide antitumor cytotoxicity triggered by the interaction of the Fc portion of the antibody ...
Joshua D Brody, Aurélien Marabelle, Roch Houot   +2 more
exaly   +3 more sources

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Use of microcalorimetry in analysing the kinetics of ADCC

Journal of Immunological Methods, 1986
Microcalorimetry was found to be a useful technique for the demonstration of antibody-dependent cellular cytotoxicity (ADCC) against human melanoma cells mediated by a heterologous rabbit antiserum and two monoclonal antibodies in combination with human peripheral blood lymphocytes as effector cells.
J, Ankerst, H O, Sjögren, R, Fäldt
openaire   +2 more sources

lymphocyte and ADCC responses

1995
Abstract Infection with HIV-1 (or HIV-2 or SIV) induces initial and long-lasting high levels of MHC class I restricted CD8-positive cytotoxic T lymphocytes (CTL) which interact through their specific T cell receptors (TCRs) with processed viral fragments (peptides) presented on the surface of infected cells in association with an MHC ...
Frances Gotch, Kristina Broliden
openaire   +1 more source

The Utility of ADCC Responses in HIV Infection

Current HIV Research, 2008
Simple antibodies or vector-induced T cell immunity are unable to provide broad immunity to HIV. Although broadly reactive neutralising antibodies are a goal of vaccination, this remains elusive. There is growing evidence that HIV-specific antibodies that mediate their activity via the Fc-receptor, such as antibody dependent cellular cytotoxicity (ADCC)
Amy, Chung, Erik, Rollman, Susanne, Johansson, Stephen J, Kent, Ivan, Stratov   +4 more
openaire   +2 more sources