Results 51 to 60 of about 330,805 (265)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A Theory of Natural Addiction

, 2007
Economic theories of rational addiction aim to describe consumer behavior in the presence of habit-forming goods. We provide a biological foundation for this body of work by formally specifying conditions under which it is optimal to form a habit.
Tasnádi, Attila, Trenton G. Smith, Attila Tasnádi, Smith, Trenton G.   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Treat addicts, not the addiction [PDF]

BMJ, 2008
Rehm and Fischer, in calling for what amounts to the legalising of heroin,1 have selected evidence to support their view. They did, however, not include the …
openaire   +1 more source

British journal of addiction.

, 1903
Contains papers read at the quarterly meetings of the society, and extracts from the discussions following them with other communications dealing with alcohol and alcoholism.Title varies slightly.Title from cover.None published July-Dec.
Society for the Study of Addiction to Alcohol and Other Drugs., Society for the Study of Inebriety (Alcoholism and Drug Addiction)   +1 more
core  

Video game characteristics, happiness and flow as predictors of addiction among video game players: A pilot study.

, 2013
AIMS: Video games provide opportunities for positive psychological experiences such as flow-like phenomena during play and general happiness that could be associated with gaming achievements.
Williams, Glenn A., Hull, Damien C., Williams, GA, Griffiths, Mark D., Damien C. Hull, Griffiths, MD, Mark D. Griffiths, Glenn A. Williams, Hull, DC   +8 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Is Sex Addiction an Addiction?

Edelweiss: Psychiatry Open Access, 2020
In the past decade or so there has been a development for the addiction paradigm to be applied to sexual behaviors. An increasing number of people are reporting excessive thoughts or behavior that is sexual in nature, and that they claim causes them suffering. They attribute this suffering as sex "addiction" [1].
openaire   +1 more source

Commentary on muscle dysmorphia as an addiction: a response to Grant (2015) and Nieuwoudt (2015) [PDF]

, 2015
Background: Following the publication of our paper ‘Muscle Dysmorphia: Could it be classified as an addiction to body image?’ in the Journal of Behavioral Addictions, two commentaries by Jon Grant and Johanna Nieuwoudt were published in response to our ...
Foster, Andrew, Foster, AC, Shorter, Gillian W; id_orcid, Shorter, Gillian, Mark Griffiths, Griffiths, MD, Shorter, Gillian W, Foster, Andrew C, Gillian Shorter, Andrew Foster, Shorter, GW, Griffiths, Mark D, Griffiths, Mark   +12 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source