Results 11 to 20 of about 5,148 (157)
Clinical Management Issues, 2014 Adefovir dipivoxil is a nucleotide analog reverse transcriptase inhibitor used to treat adult patients affected by HBeAg-positive and HBeAg-negative chronic hepatitis B and with clinical evidence of lamivudine-resistant hepatitis B virus (HBV).
Orietta Staltari +5 more
doaj +1 more source
Journal of Pharmaceutical Analysis, 2012 Electrochemical reduction behavior of Adefovir was studied using Hanging Mercury Drop Electrode (HMDE) in BrittonâRobinson (BR) buffer solution. Voltammetric study showed one well-defined reduction peak in the potential range â1.2 to â1.4Â V (vs ...
Rajeev Jain, Ramkishor Sharma
doaj +1 more source
Tenofovir has inferior efficacy in adefovir-experienced chronic hepatitis B patients compared to nucleos(t)ide-naïve patients [PDF]
Clinical and Molecular Hepatology, 2017 Background/Aims A recent study reported that entecavir had inferior efficacy in nucleos(t)ide analogue (NA)-experienced chronic hepatitis B (CHB) patients compared to NA-naïve patients.
Goh Eun Chung +11 more
doaj +1 more source
Virology Journal, 2011 Chronic viral hepatitis B remains a global public health concern. Currently, several drugs, such as tenofovir and adefovir, are recommended for treatment of patients with chronic hepatitis B.
Dai Xia-Hong +6 more
doaj +1 more source
Mediators of Inflammation, 2010 Adefovir dipivoxil treatment has significantly improved the outcome of chronic hepatitis B virus (HBV) infection. However, it remains largely unknown how immune system responds to the treatment.
Yanfang Jiang +8 more
doaj +1 more source
Differential binding of tenofovir and adefovir to reverse transcriptase of hepatitis B virus. [PDF]
PLoS ONE, 2014 Resistance of the reverse transcriptase (RT) of hepatitis B virus (HBV) to the tenofovir nucleotide drug has not been observed since its introduction for treatment of hepatitis B virus (HBV) infection in 2008. In contrast, frequent viral breakthrough and
Formijn J van Hemert +2 more
doaj +1 more source
Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B [PDF]
Türk Osteoporoz Dergisi, 2018 Adefovir dipivoxil (ADV) is a nucleotide analogue used in the chronic hepatitis B treatment. Proximal renal tubular dysfunction is one of the adverse effects of this agent and characterized with hypophosphatemia and osteomalacia.
Sevilay Batıbay +5 more
doaj +1 more source
Viruses, 2012 When HIV-1 is exposed to lamivudine (3TC) at inhibitory concentrations, resistant variants carrying the reverse transcriptase (RT) substitution M184V emerge rapidly. This substitution confers high-level 3TC resistance and increased RT fidelity.
Barbara A. Rath +3 more
doaj +1 more source
Chronic hepatitis B virus and liver fibrosis: A mathematical model. [PDF]
PLoS ONE, 2018 Hepatitis B virus (HBV) infection is a liver disorder that can result in cirrhosis, liver failure and hepatocellular carcinoma. HBV infection remains a major global health problem, as it affects more 350 million people chronically and kills roughly 600 ...
Avner Friedman, Nourridine Siewe
doaj +1 more source
BMC Nephrology, 2017 Background An increasing number of case reports suggest that acquired renal Fanconi syndrome may be associated with prolonged use of adefovir against hepatitis B virus.
Jueying Lin, Yufeng Zhuo, Dongdong Zhang
doaj +1 more source