Results 191 to 200 of about 401,272 (328)

Engineering Adenine Deaminase TadA for Precise and PAM‐Flexible Point Mutagenesis and Gradient‐Tuning Endogenous Protein Design

Advanced Science, EarlyView.
Base editing enables precise nucleotide substitutions but limited by bystander editing. This study engineers plant base editors by fusing optimized TadA variants with PAM‐flexible SpRY nickase, enabling A‐to‐G, C‐to‐T, and dual‐base conversions in a highly condensed window (≤3 nucleotides). Additionally, TadDBE (TadA Dual‐Base Editor)‐mediated directed
Kangli Sun, Si Cheng, Nan Chai, Jianing Mi, Ruixiang Zhang, Qian Qian, Zhiye Zheng, Ke Chen, Dongchang Zeng, Xin Peng, Mengyuan Shen, Degui Zhou, Qinlong Zhu, Qi Liu, Jiantao Tan   +14 more
wiley   +1 more source

Comparison of Adenine-Induced Rat Models for Vascular Calcification in Chronic Kidney Disease. [PDF]

Biology (Basel)
Kang HW, Kim JH, Yoon AR, Kim J, Kim J, Kyung MG, Lee DY.   +6 more
europepmc   +1 more source

FLAVIN-ADENINE DINUCLEOTIDE-SYNTHESIZING ENZYME IN EREMOTHECIUM ASHBYII

, 1961
Tokio Kobayashi, Takuji Suzue
openalex   +2 more sources

Engineered Fusion Enzyme‐Mediated Non‐Consecutive Cyclization‐Glycosylation Enables Heterologous Synthesis of Antifungal Enfumafungin

Advanced Science, EarlyView.
The artificial biosynthetic pathway potentially involved in biosynthesis of enfumafungin is first reconstructed in an optimized Aspergillus oryzae chassis with the increased site‐specific integration efficiency and shortened time for marker recycling, which requires an artificial fusion enzyme EfuA(TC)FsoA(GT).
Yaohui Gao, Jianming Lv, Yue Zhong, Zhiqin Cao, Rui Luo, Yue Qi, Gaoqian Wang, Shaoyang Li, Guodong Chen, Dan Hu, Hao Gao, Xinsheng Yao   +11 more
wiley   +1 more source

Expression of concern: Flavin-adenine-dinucleotide gold complex nanoparticles: chemical modeling design, physico-chemical assessment and perspectives in nanomedicine. [PDF]

Nanoscale Adv
Arib C, Bouchemal N, Barile M, Paleni D, Djaker N, Dupont N, Spadavecchia J.   +6 more
europepmc   +1 more source

Studies on the Biosynthesis of Nicotinamide Adenine Dinucleotide

, 1963
Yasutomi Nishizuka, Osamu Hayaishi
openalex   +1 more source

The kinetics of the reversible inhibition of heart lactate dehydrogenase through the formation of the enzyme–oxidized nicotinamide–adenine dinucleotide–pyruvate compound [PDF]

, 1968
H. Gutfreund, Robin Cantwell, C.H. McMurray, Richard S. Criddle, Gary M. Hathaway   +4 more
openalex   +1 more source

Heme/NADH Mimics Co‐Decorated Allosteric Capsules for Regulating Oxygen Activation and Upregulating Intracellular Methionine Depletion

Advanced Science, EarlyView.
Through modifying the switchable µ‐oxo bridged FeIII‐porphyrins moiety and NADH mimics into a metal‐organic capsule, multiple responsive manners for O2 activation, chemical oxygenation and metabolic transformation have been demonstrated for upregulating intracellular methionine depletion and accumulation of methionine sulfoxide to achieve effective ...
Chunming Ma, Yihao Zhang, Junkai Cai, Baotong Ding, Yang Jiao, Chunying Duan   +5 more
wiley   +1 more source

Artificial Seawater Models Affect Sorption of Adenine and Related Molecules Sorption onto Montmorillonite: Implications for Early Mars and Earth Oceans. [PDF]

ACS Omega
Ferreira GW, Pintor BE, Samulewski RB, Zaia DAM.   +3 more
europepmc   +1 more source

Differences between the Reactivity of Endogenous and Exogenous Adenine Nucleotides in Mitochondria as Studied at Low Temperature [PDF]

, 1968
H. W. Heldt, Martin Klingenberg
openalex   +1 more source