Results 191 to 200 of about 399,190 (328)

Mutation in the rat interleukin 34 gene impacts macrophage development, homeostasis, and inflammation. [PDF]

Life Sci Alliance
Huang S, Patkar OL, Schulze S, Carter-Cusack D, Millard S, Ranpura G, Green EK, Maxwell E, Kanesarajah J, Cowin G, Stimson D, Kurniawan ND, Keshvari S, Allavena R, Pettit AR, Irvine KM, Hume DA.   +16 more
europepmc   +1 more source

Engineering Adenine Deaminase TadA for Precise and PAM‐Flexible Point Mutagenesis and Gradient‐Tuning Endogenous Protein Design

Advanced Science, EarlyView.
Base editing enables precise nucleotide substitutions but limited by bystander editing. This study engineers plant base editors by fusing optimized TadA variants with PAM‐flexible SpRY nickase, enabling A‐to‐G, C‐to‐T, and dual‐base conversions in a highly condensed window (≤3 nucleotides). Additionally, TadDBE (TadA Dual‐Base Editor)‐mediated directed
Kangli Sun, Si Cheng, Nan Chai, Jianing Mi, Ruixiang Zhang, Qian Qian, Zhiye Zheng, Ke Chen, Dongchang Zeng, Xin Peng, Mengyuan Shen, Degui Zhou, Qinlong Zhu, Qi Liu, Jiantao Tan   +14 more
wiley   +1 more source

A SIMPLIFIED PREPARATION METHOD OF P32- LABELED FLAVIN MONONUCLEOTIDE AND FLAVIN-ADENINE DINUCLEOTIDE AND THEIR APPLICATION TO BIOCHEMICAL RESEARCHES

, 1959
K Hotta, Isao Ishiguro, Mamoru Sugiura, Nobuhiko Katunuma, Kazutoshi Kojima, TOSHIYUKI HISHIKI, Yoshio Ikegami   +6 more
openalex   +2 more sources

Heme/NADH Mimics Co‐Decorated Allosteric Capsules for Regulating Oxygen Activation and Upregulating Intracellular Methionine Depletion

Advanced Science, EarlyView.
Through modifying the switchable µ‐oxo bridged FeIII‐porphyrins moiety and NADH mimics into a metal‐organic capsule, multiple responsive manners for O2 activation, chemical oxygenation and metabolic transformation have been demonstrated for upregulating intracellular methionine depletion and accumulation of methionine sulfoxide to achieve effective ...
Chunming Ma, Yihao Zhang, Junkai Cai, Baotong Ding, Yang Jiao, Chunying Duan   +5 more
wiley   +1 more source

Influence of Tariquidar, an ABC Transporter Inhibitor, on the Ca²⁺-Dependent Mitochondrial Permeability Transition Pore. [PDF]

Pharmaceuticals (Basel)
Fedotcheva TA, Kruglov AG, Fedotcheva NI.   +2 more
europepmc   +1 more source

Characterization and Reuse of Lithium‐ion Battery Cathode Material Recovered Through a Bacterial Process

Advanced Energy Materials, EarlyView.
A sustainable bacteria‐based lithium‐ion battery cathode recycling method is optimized using engineering biology. The resulting biomineralized manganese carbonate species is found to be easily converted into an electrode material, via simple calcination.
Virginia Echavarri‐Bravo, Isolde Marsland, Mai‐Britt V. Jensen, Caroline Kirk, Louise E. Horsfall   +4 more
wiley   +1 more source

Structural basis of cytokinin transport by the Arabidopsis AZG2. [PDF]

Nat Commun
Wei H, Yang Z, Liu H, Ying W, Gao Y, Zhu L, Liu X, Sun L.   +7 more
europepmc   +1 more source

Variation of Nicotinamide Adenine Dinucleotide Phosphate Level in Bean Hypocotyls in Relation to O₂ Concentration

, 1966
Yukio Yamamoto
openalex   +2 more sources

Adenine nucleotides and magnesium ions in relation to control of mammalian cerebral-cortex hexokinase [PDF]

, 1969
H. S. Bachelard, Peter S. Goldfarb
openalex   +1 more source

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

Aggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky, Olesya V. Stepanenko, Olga V. Stepanenko, Anna I. Sulatskaya   +3 more
wiley   +1 more source