Results 31 to 40 of about 487,247 (373)
Trypanosoma brucei methylthioadenosine phosphorylase protects the parasite from the antitrypanosomal effect of deoxyadenosine [PDF]
, 2016 Trypanosoma brucei causes African sleeping sickness for which no vaccine exists and available treatments are of limited use due to their high toxicity or lack of efficacy. T.
de Koning, Harry P. +4 more
core +1 more source
Interaction of low-energy electrons with the purine bases, nucleosides, and nucleotides of DNA [PDF]
, 2006 The authors report results from computational studies of the interaction of low-energy electrons with the purine bases of DNA, adenine and guanine, as well as with the associated nucleosides, deoxyadenosine and deoxyguanosine, and the nucleotide ...
McKoy, Vincent, Winstead, Carl
core +1 more source
Sensors, 2017 A new electrochemical sensor based on a Nafion, aminated reduced graphene oxide and chitosan functional membrane-modified glassy carbon electrode was proposed for the simultaneous detection of adenine and guanine. Fourier transform-infrared spectrometry (
Di Li +6 more
doaj +1 more source
Fluorescence kinetics of flavin adenine dinucleotide in different microenvironments [PDF]
, 2013 Fluorescence kinetics of flavin adenine dinucleotide was measured in a wide time and spectral range in different media, affecting its intra- end extramolecular interactions, and analyzed by a new method based on compressed ...
A. Makai +18 more
core +2 more sources
Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction
Nature Biotechnology, 2018 Base editors enable targeted single-nucleotide conversions in genomic DNA. Here we show that expression levels are a bottleneck in base-editing efficiency.
Luke W. Koblan +8 more
semanticscholar +1 more source
The influence of adenine and benzyladenine on rooting and development of Fuchsia hybrida cuttings
Acta Agrobotanica, 2012 Cytokinins are a group of plant hormones stimulating, among others, axillary bud formation and inhibiting rhizogenesis. Adenine, their common component, often expresses cytokinin-like activity in plant development.
Katarzyna Wróblewska
doaj +1 more source
DNA capture by a CRISPR-Cas9–guided adenine base editor
Science, 2020 Secrets of a fast base editor CRISPR-Cas9 base editors comprise RNA-guided Cas proteins fused to an enzyme that can deaminate a DNA nucleoside. No natural enzyme deaminates adenine in DNA, and so a breakthrough came when a natural transfer RNA deaminase ...
Audrone Lapinaite +8 more
semanticscholar +1 more source
Silver-Based SERS Pico-Molar Adenine Sensor
Biosensors, 2020 Adenine is an important molecule for biomedical and agricultural research and applications. The detection of low concentration adenine molecules is thus desirable.
Yonhua Tzeng, Bo-Yi Lin
doaj +1 more source
Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice
Science, 2019 Spotting off-targets from gene editing Unintended genomic modifications limit the potential therapeutic use of gene-editing tools. Available methods to find off-targets generally do not work in vivo or detect single-nucleotide changes.
Shuai Jin +10 more
semanticscholar +1 more source
Materials Research Express, 2021 A porous material (PEA) was prepared by the ring opening polymerization of polyethylene glycol diglycidyl ether with adenine in a simple sol-gel method. The structure and composition of PEA were characterized by SEM, FT-IR, BET and XRD.
Longfei Zhang +7 more
doaj +1 more source