Can adenine nucleotides predict primary nonfunction of the human liver homograft? [PDF]
Sixty-eight primary liver grafts were analyzed to see whether adenine nucleotides (AN: ATP, ADP, and AMP) or purine catabolites (PC: adenosine, inosine, hypoxanthine, and xanthine) of tissue or effluent can predict primary graft nonfunction.
Bronsther, O +8 more
core +1 more source
(1RS,2RS,6RS)-2-(6-Amino-9H-purin-9-yl)-8-azaspiro[5.6]dodec-10-en-1-ol Dihydrochloride
The title compound (1RS,2RS,6RS)-2-(6-Amino-9H-purin-9-yl)-8-azaspiro[5.6]dodec-10-en-1-ol dihydrochloride was synthesized for the first time in two steps, the first of which was a regioselectivity of epoxide ring-opening reaction under the action of ...
Ildar R. Iusupov +3 more
doaj +1 more source
The Dissipative Photochemical Origin of Life: UVC Abiogenesis of Adenine
The non-equilibrium thermodynamics and the photochemical reaction mechanisms are described which may have been involved in the dissipative structuring, proliferation and complexation of the fundamental molecules of life from simpler and more common ...
Karo Michaelian
doaj +1 more source
Adenine deaminase and adenine utilization in Saccharomyces cerevisiae [PDF]
Compared with other purine salvage and nitrogen catabolism enzymatic activities, adenine deaminase (adenine aminohydrolase [AAH]; EC 3.5.4.2) activity in Saccharomyces cerevisiae is uniquely regulated. AAH specific activity is not induced by adenine and is reduced sevenfold when cells are cultivated in medium containing proline in place of ammonium as ...
openaire +2 more sources
Non-Empirically Tuned Range-Separated DFT Accurately Predicts Both Fundamental and Excitation Gaps in DNA and RNA Nucleobases [PDF]
Using a non-empirically tuned range-separated DFT approach, we study both the quasiparticle properties (HOMO-LUMO fundamental gaps) and excitation energies of DNA and RNA nucleobases (adenine, thymine, cytosine, guanine, and uracil).
Foster, Michael E., Wong, Bryan M.
core +2 more sources
Adenine decreases hypertrophic effects through interleukin-18 receptor
Cardiac hypertrophy is the main cause of heart failure. Levels of circulating interleukin-18 (IL-18) have been reported to increase in congestive heart disease and cardiac hypertrophy. Relationships among IL-18 levels, IL-18 receptor (IL-18R) expression,
Yi-Feng Yang, Yao-Jen Liang
doaj +1 more source
Two small-volume electrochemical cells for the measurement of surface enhanced Raman scattering [PDF]
Two electrochemical cells, for performing surface enhanced Raman scattering (SERS), with submillilitre volumes are presented. One of the cells is especially developed for use in a Raman microspectrometer.
Greve, J. +5 more
core +2 more sources
Infrared Spectral Signatures of Nucleobases in Interstellar Ices I: Purines
The purine nucleobases adenine and guanine are complex organic molecules that are essential for life. Despite their ubiquitous presence on Earth, purines have yet to be detected in observations of astronomical environments.
Caroline Antunes Rosa +11 more
doaj +1 more source
Back-electron transfer suppresses the periodic length dependence of DNA-mediated charge transport across adenine tracts [PDF]
DNA-mediated charge transport (CT) is exquisitely sensitive to the integrity of the bridging π-stack and is characterized by a shallow distance dependence. These properties are obscured by poor coupling between the donor/acceptor pair and the DNA bridge,
Augustyn, Katherine E. +4 more
core +2 more sources
Cisplatin has been widely used in cancer treatments. Recent evidence indicates that adenine has potential anticancer activities against various types of cancers. However, the effects of the combination of adenine and cisplatin on hepatocellular carcinoma
Jhen-Yu Huang +4 more
doaj +1 more source

