Results 91 to 100 of about 353,387 (184)

Cardioprotection by ischemic preconditioning preserves mitochondrial function and functional coupling between adenine nucleotide translocase and creatine kinase.

, 2001
International audienceM. N. Laclau, S. Boudina, J. B. Thambo, L. Tariosse, G. Gouverneur, S. Bonoron-Adèle, V. A. Saks, K. D. Garlid and P. Dos Santos. Cardioprotection by Ischemic Preconditioning Preserves Mitochondrial Function and Functional Coupling ...
Garlid, K. D., Laclau, Muriel, N., Tariosse, Liliane, Thambo, J. B., Saks, Valdur, A, Gouverneur, Gérard, dos Santos, Pierre, Boudina, Sihem, Bonoron-Adèle, Simone   +8 more
core   +1 more source

Effect of aging and acetyl-l-carnitine on the activity of cytochrome oxidase and adenine nucleotide translocase in rat heart mitochondria [PDF]

, 1994
The effect of aging and treatment with acetyl-l-carnitine on the activity of cytochrome oxidase and adenine nucleotide translocase in rat heart mitochondria was studied.
Giuseppe Paradies, Francesca Maria Ruggiero, Gadaleta, Maria Nicola, Maria Nicola Gadaleta, Ernesto Quagliariello, Giuseppe Petrosillo, Paradies, Giuseppe, Quagliariello, Ernesto, Ruggiero, Francesca Maria, Petrosillo, Giuseppe   +9 more
core   +1 more source

Redox signals and oxidative stress in the control of mitochondrial protein import

Protein Science, Volume 35, Issue 7, July 2026.
Abstract Mitochondrial protein import is essential for organelle biogenesis and cellular homeostasis. It operates in an environment that is intrinsically shaped by redox chemistry. Mitochondria are major sources of reactive oxygen species (ROS), which arise as by‐products of oxidative phosphorylation. Cells therefore maintain sophisticated ROS‐handling
Lidwina Hasberg, Viktoria Katharina Lauterbach, Torsten Ochsenreiter, Jan Riemer   +3 more
wiley   +1 more source

Protein Homeostasis and Mitochondrial Quality Control in Neurodegeneration

WIREs Mechanisms of Disease, Volume 18, Issue 4, July/August 2026.
Quality control pathways form an integrated proteostasis–mitochondrial quality control axis that maintains mitochondrial and cellular homeostasis. Failure of this coordinated network drives neuronal decline and contributes to neurodegeneration. ABSTRACT Quality control (QC) processes include a network of cellular pathways that prevent the accumulation ...
Rosa Di Lorenzo, Rola S. Zeidan, Riccardo Calvani, Vito Pesce, Emanuele Marzetti, Anna Picca   +5 more
wiley   +1 more source

Mitochondrial Dysfunction at the Crossroads of Necroptosis: Mechanisms, Molecular Mediators, and Therapeutic Opportunities

Journal of Cellular and Molecular Medicine, Volume 30, Issue 14, July 2026.
ABSTRACT The conceptual landscape of cell death has evolved beyond the traditional dichotomy of apoptosis and necrosis to encompass diverse regulated pathways including necroptosis, autophagy, ferroptosis, and pyroptosis. Necroptosis, a caspase‐independent inflammatory form of programmed cell death, has emerged as a critical driver of the pathogenesis ...
Fengxin Wang, Haiying Rui, Dandan Qin, Huaxiang Yu, Dan Zou, Wenyi Zou, Yuting Li, Ran Li, Yuguo Chen, Li Xue   +9 more
wiley   +1 more source

Intracellular ATP influences synaptic plasticity in area CA1 of rat hippocampus via metabolism to adenosine and activity-dependent activation of adenosine A1 receptors [PDF]

, 2011
The extent to which brain slices reflect the energetic status of the in vivo brain has been a subject of debate. We addressed this issue to investigate the recovery of energetic parameters and adenine nucleotides in rat hippocampal slices and the ...
D. Grahame Hardie, Hardie, D. G. (D. Grahame), Naomi Pentland, Simon Hawley, Frenguelli, Bruno, Doney, Alexander S., Pentland, Naomi, Frenguelli, Bruno G., Stephanie zur Nedden, Hawley, Simon, Alexander S. Doney, Bruno G. Frenguelli, Hardie, D. Grahame, Doney, Alexander S.; id_orcid, Zur Nedden, Stephanie   +14 more
core   +1 more source

Acyl-CoA inhibition of adenine nucleotide translocation in ischemic myocardium

, 1975
The translocation of adenine nucleotides across the inner mitochondrial membrane and the tissue concentration of long-chain acyl-CoA esters were studied in dog heart after experimental myocardial ischemia.
AL Shug, null Koke, JD Folts, N Bittar, E Shrago   +4 more
core   +1 more source

[Analysis of mechanism of work of mitochondrial adenine nucleotide translocase using mathematical models]

, 2003
International audienceThe kinetics of exchange of adenine nucleotides in a system with reconstituted mitochondrial adenine nucleotide translocase (ANT) was simulated mathematically to analyze the basic mechanisms of ANT functioning. Two known alternative
Saks, Valdur, A, Aliev, Mayis, K
core   +1 more source

Influence of Tariquidar, an ABC Transporter Inhibitor, on the Ca²⁺-Dependent Mitochondrial Permeability Transition Pore

Pharmaceuticals
Background: Tariquidar (Tq) is an inhibitor of the multidrug resistance (MDR) proteins relevant to ATP-binding cassette transporters (ABC transporters), which suppresses the ATP-dependent efflux of a variety of hydrophilic and amphipathic compounds ...
Tatiana A. Fedotcheva, Alexey G. Kruglov, Nadezhda I. Fedotcheva   +2 more
doaj   +1 more source

Overexpression of adenine nucleotide translocase reduces Ca2+ signal transmission between the ER and mitochondria

, 2006
The adenine nucleotide translocase (ANT), besides transferring ATP from the mitochondrial matrix to the rest of the cell, has also been proposed to be involved in mitochondrial permeability transition (MPT), and accordingly in mitochondrial Ca2 ...
PINTON, Paolo, WASILEWSKI M, Pinton P, SZABADKAI, GYORGY, WIECKOWSKI, Mariusz, RIZZUTO, ROSARIO, DUSZYNSKI J, P. PINTON, WIECKOWSKI MR   +8 more
core   +1 more source