NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice.
PLoS ONE, 2019 Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-limiting enzyme in mammalian nicotinamide adenine dinucleotide (NAD)+ biosynthesis. Through its NAD+-biosynthetic activity, NAMPT influences the activity of NAD+-dependent enzymes, such as sirtuins.
Xiwen Xiong +9 more
doaj +1 more source
, 2014 Most organisms possess a common molecular machinery that governs cellular and tissue circadian rhythmicity through a roughly 24-hour transcription-translation feedback loop.
Brandauer, Josef +2 more
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Die Funktion des Responseregulators ARR2 in der Entwicklung von Arabidopsis thaliana [PDF]
, 2004 In dieser Arbeit konnte mittels physiologischer Experimente, Expressionsanalysen, Phosphorylierungsassays und Transaktivierungsanalysen eine komplexe Funktion von ARR2 in verschiedenen Signaltransduktionswegen von Arabidopsis aufgedeckt werden.
Haß, Claudia
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Molecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Proteome-wide analysis of Trypanosoma cruzi exponential and stationary growth phases reveals a subcellular compartment-specific regulation [PDF]
, 2018 Trypanosoma cruzi, the etiologic agent of Chagas disease, cycles through different life stages characterized by defined molecular traits associated with the proliferative or differentiation state. In particular, T. cruzi epimastigotes are the replicative
Avila, Carla Cristi +10 more
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A Rapid and Specific Method for Separation of Bound and Free Antigen in Radioimmunoassay Systems [PDF]
, 1979 Peer ...
Müller, O. A. +3 more
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A case of right ureteral stone with complete deficiency of adenine phosphoribosyltransferase [PDF]
, 1985 We report a case of a 34-year-old male, who had urinary tract calculus, caused by complete deficiency of adenine phosphoribosyltransferase. Ureterolithotomy was performed on February 28, 1983.
伊藤, 哲二 +4 more
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Metabolomic profiling of the synergistic effects of melittin in combination with cisplatin on ovarian cancer cells [PDF]
, 2017 Melittin, the main peptide present in bee venom, has been proposed as having potential for anticancer therapy; the addition of melittin to cisplatin, a first line treatment for ovarian cancer, may increase the therapeutic response in cancer treatment via
Alonezi, Sanad +10 more
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Metabolic and neurobehavioral disturbances induced by purine recycling deficiency in Drosophila
eLifeAdenine phosphoribosyltransferase (APRT) and hypoxanthine-guanine phosphoribosyltransferase (HGPRT) are two structurally related enzymes involved in purine recycling in humans.
Céline Petitgas +11 more
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Adenine Phosphoribosyltransferase from Monkey Liver
Journal of Biological Chemistry, 1969 Abstract The structural requirements for the binding of purines to adenine phosphoribosyltransferase from monkey liver were explored by the determination of the Ki values for 67 purines and purine analogues. Adenine was bound 40 times better than the most effectively bound analogues.
George H. Hitchings +3 more
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