Results 101 to 110 of about 87,339 (215)

Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani [PDF]

, 1999
Cynthia L. Phillips
openalex   +1 more source

Metabolic and neurobehavioral disturbances induced by purine recycling deficiency in Drosophila

eLife
Adenine phosphoribosyltransferase (APRT) and hypoxanthine-guanine phosphoribosyltransferase (HGPRT) are two structurally related enzymes involved in purine recycling in humans.
Céline Petitgas, Laurent Seugnet, Amina Dulac, Giorgio Matassi, Ali Mteyrek, Rebecca Fima, Marion Strehaiano, Joana Dagorret, Baya Chérif-Zahar, Sandrine Marie, Irène Ceballos-Picot, Serge Birman   +11 more
doaj   +1 more source

Nucleotide sequence and organization of the mouse adenine phosphoribosyltransferase gene: presence of a coding region common to animal and bacterial phosphoribosyltransferases that has a variable intron/exon arrangement. [PDF]

, 1985
Michael Dush, James M. Sikela, SA Khan, Jay A. Tischfield, P J Stambrook   +4 more
openalex   +1 more source

Nicotinamide phosphoribosyltransferase prompts bleomycin-induced pulmonary fibrosis by driving macrophage M2 polarization in mice

Theranostics
Rationale: Idiopathic pulmonary fibrosis (IPF) is an irreversible, fatal interstitial lung disease lacking specific therapeutics. Nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the nicotinamide adenine dinucleotide (NAD ...
Yaling Chen, Tong Wang, Fuxiang Liang, Jia Han, Zhiling Lou, Yifan Yu, Jinsheng Li, Tian-Wei Zhan, Yuqing Gu, Lingjun Dong, Bo Jiang, Weiping Zhang, Ming Wu, Yunbi Lu   +13 more
semanticscholar   +1 more source

NAD+ enhancers as therapeutic agents in the cardiorenal axis

Cell Communication and Signaling
Cardiorenal diseases represent a complex interplay between heart failure and renal dysfunction, being clinically classified as cardiorenal syndromes (CRS).
Mariano Marín-Blázquez, Jordi Rovira, María José Ramírez-Bajo, Rubén Zapata-Pérez, Rubén Rabadán-Ros   +4 more
doaj   +1 more source

Robust survival-based RNAi using in tandem silencing of adenine phosphoribosyltransferase [PDF]

, 2020
Robert G. Orr, Stephen J. Foley, Giulia Galotto, Boyuan Liu, Luis Vidali   +4 more
openalex   +1 more source

Function of NAD metabolism in white adipose tissue: lessons from mouse models

Adipocyte
Nicotinamide Adenine Dinucleotide (NAD) is an endogenous substance in redox reactions and regulates various functions in metabolism. NAD and its precursors are known for their anti-ageing and anti-obesity properties and are mainly active in the liver and
So Young Kwon, Yoon Jung Park
doaj   +1 more source

A new simplified radioisotope method for determining hypoxanthine-guanine phosphoribosyltransferase and adenine phosphoribosyltransferase with the use of thin-layer radio-chromatogram scanner.

, 1977
Hideaki Koga, Shuji Kumano, Ryohei Ogura
openalex   +2 more sources

Adenine Phosphoribosyltransferase Deficiency Presenting with Supposed ‘Uric Acid’ Stones: Pitfalls of Diagnosis¹ [PDF]

, 1978
H. Anne Simmonds, Amrik Sahota, C. F. Potter, J. S. Cameron, Geoffrey Rose, DI Williams, T M Barratt, D. G. ARKELL, K. J. Van Acker   +8 more
openalex   +1 more source

Hypothalamic astrocyte NAD+ salvage pathway mediates the coupling of dietary fat overconsumption in a mouse model of obesity

Nature Communications
Nicotinamide adenine dinucleotide (NAD)+ serves as a crucial coenzyme in numerous essential biological reactions, and its cellular availability relies on the activity of the nicotinamide phosphoribosyltransferase (NAMPT)-catalyzed salvage pathway.
Jae Woo Park, Se Eun Park, Wuhyun Koh, Won Hee Jang, Jong Han Choi, Eun Roh, Gil Myoung Kang, Seong Jun Kim, Hyo Sun Lim, Chae Beom Park, So Yeon Jeong, Sang Yun Moon, Chan Hee Lee, Sang Yeob Kim, Hyung Jin Choi, Se Hee Min, C. Justin Lee, Min-Seon Kim   +17 more
doaj   +1 more source