Results 51 to 60 of about 574,701 (296)
Case Reports in Oncology, 2020 Adenocarcinoma and adenosquamous carcinoma (AS) are 2 rare histological types of cervix uteri cancer constituting almost 20% of all cervix cancers, leading to a lack in patient management guidelines.
Mihai Teodor Georgescu +3 more
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Calcified Urachal Cancer Managed by Partial Cystectomy: A Case Report
Research and Reports in Urology, 2021 Taras Hladun,1 Jakub Ratajczak,1 Maciej Salagierski2 1Urology Department, Regional Specialized Hospital in Nowa Sól, Nowa Sól, 67-100, Poland; 2Department of Urology, Collegium Medicum, University of Zielona Góra, Zielona Góra, 65-046 ...
Hladun T, Ratajczak J, Salagierski M
doaj
Diagnostic Pathology, 2011 Low-grade cribriform cystadenocarcinoma (LGCCA) is a rare tumor of the salivary gland that exhibits clinically indolent behavior. In this paper, we present a case of invasive adenocarcinoma of the accessory parotid gland in a young male that exhibited ...
Nakatsuka Shin-ichi +8 more
doaj +1 more source
Case Reports in Gastroenterology, 2021 Intussusception in adults is a challenging diagnosis that often requires a high degree of suspicion. In adults presenting with symptoms, almost 90% have underlying neoplasms.
Zeena Ayad Qiryaqoz +2 more
doaj +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
PATTERN OF HISTOPATHOLOGICAL LESIONS IN UTERINE CORPUS OF HYSTERECTOMY SPECIMENS
Gomal Journal of Medical Sciences, 2015 Background: Hysterectomy is one of the common gynecological surgical procedures throughout the world. The objective of this study was to see the pattern of histopathological lesions in uterine corpus of hysterectomy specimens.
Mohammad Sajjad +3 more
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Early glandular neoplasia of the lung
Respiratory Research, 2000 Although bronchogenic carcinomas progress through a very well defined sequence of metaplasia, dysplasia and carcinoma in situ, very little is known about the early progression of glandular neoplasms of the lung.
Westra William H
doaj +1 more source
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source