Results 111 to 120 of about 34,616 (236)

Motor‐Assisted Co‐Migration of Intracellular Organelles and Microtubules as a Mechanism for Directed Cargo Transport

BioEssays, Volume 48, Issue 3, March 2026.
Directional intracellular cargo transport is traditionally attributed to motor stepping along stationary microtubule (MT) tracks. We propose a complementary mechanism of cargo co‐migration with moving MTs. This mode requires cargo–MT tethering and directed MT motion.
Chuying Zhou, Mineko Kengaku
wiley   +1 more source

An uncommon intersection: Familial adenomatous polyposis and solid pseudopapillary neoplasm of the pancreas: A case report and review of the literature

Radiology Case Reports
The co-occurrence of both Familial Adenomatous Polyposis (FAP) and Solid Pseudopapillary Neoplasms (SPN) of the pancreas is extremely uncommon, with limited reports published in the literature. FAP is a rare inherited disorder caused by a mutation in the
Hajra Arshad, Charles K. Crawford, Elliot K. Fishman   +2 more
doaj   +1 more source

A New Germline Stop Codon Mutation in Exon 15 of the Gene Predisposing to Familial Adenomatous Polyposis

The International Journal of Biological Markers, 2013
Familial adenomatous polyposis (FAP) is an autosomal dominant disorder related to germline mutations of the adenomatous polyposis coli ( APC ) gene. It is characterized by the detection of numerous adenomatous polyps that, if untreated, develop into ...
Laura Schirosi, Marcello Pellegrino, Paolo Tarantino, Salvatore Mauro, Andrea Tinelli, Marilena Greco PhD   +5 more
doaj   +1 more source

Genetic Alterations Involved in Immune Escape Mechanisms of Circulating Tumour Cells in Colorectal Carcinogenesis

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT In colorectal cancer (CRC), circulating tumour cells (CTCs) employ genetic alterations to dodge the body's immune system. These alterations occur in specific “driver” genes, including KRAS, BRAF, p53, MYC, APC and PTEN. Changes in these genes can control how the tumour interacts with the immune system and influence the expression of immune ...
Sharmin Aktar, Matthew Masoudi, Dilpreet Moti, Vinod Gopalan, Farhadul Islam, Alfred King‐yin Lam   +5 more
wiley   +1 more source

Peripheral nerve sheath tumors in the head and neck in patients with APC gene deletion mutations: a case report and scoping review of the literature [PDF]

Clinical and Experimental Pediatrics
Adenomatous polyposis coli (APC) is a tumor suppressor gene expressed throughout the body. APC mutations increase the risk of malignancy and are often characterized by syndromes that encompass a spectrum of neoplastic manifestations, such as familial ...
Koral M. Blunt, Monirah Albathi, Miriam Conces, Tendy Chiang   +3 more
doaj   +1 more source

Pigmented Sorghum Phenolic Extracts Regulate the Expression of Cancer Development Pathway Genes in HT‐29 and Hypoxia‐Induced CCD 841 CoN Cells

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
A depiction of reconstituted red sorghum and black sorghum extract effects on HT‐29 and CCD 841 CoN cell cells at 500 and 2000 μg/mL for 12 and 24 h resulting in the decrease of cancer cell viability, modulation of mutation‐associated genes, and suppression of hypoxia and metabolic signaling.
Aduba Collins, Kenneth Chinkwo, Nidhish Francis, Abishek Bommannan Santhakumar, Christopher Blanchard   +4 more
wiley   +1 more source

Push Enteroscopic Jejunal and Ileoscopic Delivery of Fecomicrobiota Transplantation (FMT) for Treatment of Clostridioides difficile Enteritis in a Patient With a Total Colectomy and Ileal Pouch‐Anal Anastomosis (IPAA): A Case Report

JGH Open, Volume 10, Issue 3, March 2026.
ABSTRACT Clostridioides difficile infection (CDI) is recognized as the leading cause of antibiotic‐associated diarrhea. There are several case reports of C. difficile enteritis in patients who have undergone colectomy and end ileostomy or ileal pouch‐anal anastomosis. This case report describes a unique case of recurrent C.
Zoe Tan, Edward Young, Arvind Rajagopalan   +2 more
wiley   +1 more source

Multidisciplinary management and genetic findings in an Ashkenazi Jewish male: case report of pathogenic BRCA2 and adenomatous polyposis coli mutations

Academia Oncology
This case report describes the multidisciplinary management and genetic findings of a 66-year-old Ashkenazi Jewish male with a history of thyroid cancer who was diagnosed with muscle-invasive bladder cancer (MIBC) and invasive human epidermal ...
Daniela Guevara, Majd Assaad, Jyothi Manohar, Michael Sigouros, John Otilano, Abigail King, Christina Fedorov, Anna Butusova, Arina Aghajanyan, Valentin Channov, Alexandra Boyko, Olivier Elemento, Juan Miguel Mosquera, Cora N. Sternberg   +13 more
doaj   +1 more source

Trabid patient mutations impede the axonal trafficking of adenomatous polyposis coli to disrupt neurite growth. [PDF]

Elife, 2023
Frank D, Bergamasco M, Mlodzianoski MJ, Kueh A, Tsui E, Hall C, Kastrappis G, Voss AK, McLean C, Faux M, Rogers KL, Tran B, Vincan E, Komander D, Dewson G, Tran H.   +15 more
europepmc   +1 more source

Chondroitin Sulfate Proteoglycans in CNS Development and Pathophysiology

Journal of Neuroscience Research, Volume 104, Issue 3, March 2026.
Chondroitin sulfate proteoglycans (CSPGs) are critical components of the extracellular matrix in the central nervous system (CNS). In the developing CNS, CSPGs regulate neural precursor cells, neuronal migration, axon guidance, synapse organization, and peri‐neuronal net assembly.
Seyed Mojtaba Hosseini, Soheila Karimi‐Abdolrezaee   +1 more
wiley   +1 more source