Results 11 to 20 of about 22,051 (209)

APC (adenomatous polyposis coli) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on APC (adenomatous polyposis coli), with data on DNA, on the protein encoded, and where the gene is implicated.
Hamelin, P
core   +5 more sources

Familial adenomatous polyposis coli

Journal of the Belgian Society of Radiology, 2011
Background: A 53-year-old male patient with a familial history of colon carcinoma presented with stool changes and abdominal cramps. There was no weight loss nor signs of blood in the stool.
K Boeren, Y Vankan, D Perdieus
doaj   +5 more sources

Familial polyposis coli: the management of desmoid tumor bleeding [PDF]

Open Medicine, 2019
There is currently no standard treatment for desmoid tumors (DTs) associated with familial polyposis coli (FAP). Familial adenomatous polyposis in DT patients is sometimes a life-threatening condition.
Calogero Armando, Sagnelli Caterina, Carlomagno Nicola, Tammaro Vincenzo, Candida Maria, Vernillo Antonio, Peluso Gaia, Minieri Gianluca, Sica Antonello, Ciccozzi Massimo, Santangelo Michele, Dodaro Concetta Anna   +11 more
doaj   +3 more sources

Familial adenomatous polyposis: a case report

Journal of Medical Case Reports
Background Familial adenomatous polyposis is characterized by the presence of multiple colorectal adenomatous polyps and caused by germline mutations in the tumor suppressor gene and adenomatous polyposis coli, located on chromosome 5q21–q22.
Endeshaw Asaye Kindie, Tigist Desta Beyera, Ephrem Tafesse Teferi, Daniel Zemenfes Ashebir, Henok Bahru Wodajeneh   +4 more
doaj   +3 more sources

Deep vein thrombosis in a patient of adenomatous polyposis coli treated successfully with aspirin: A case report

Caspian Journal of Internal Medicine, 2016
Background: Deep vein thrombosis is an important cause of morbidity and mortality. However, its association with adenomatous polyposis coli is extremely rare.
Neha Agrawal, Tuhin Santra, Arnab Kar, Pradipta Guha, Mita Bar, Apu Adhikary, Sumana Datta   +6 more
doaj   +1 more source

Adenomatous polyposis coli in an elderly female Nigerian

Ghana Medical Journal, 2010
Colorectal cancer is reported to occur in lower rates in Africans and some of the reasons adduced include a rarity of polyposis coli syndromes. Only two cases of polyposis coli have been documented in Nigeria in the last 15 years. The present case is an elderly lady who had radiologic and colonoscopic evidence of multiple colonic polyps.
Alese, O.B, Irabor, D.O
openaire   +5 more sources

Biology of the Adenomatous Polyposis Coli Tumor Suppressor

Journal of Clinical Oncology, 2000
ABSTRACT: The adenomatous polyposis coli (APC) gene was first identified as the gene mutated in an inherited syndrome of colon cancer predisposition known as familial adenomatous polyposis coli (FAP). Mutation of APC is also found in 80% of all colorectal adenomas and carcinomas and is one of the earliest mutations in colon cancer progression. Similar
K H, Goss, J, Groden
openaire   +3 more sources

The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration. [PDF]

Sci Adv, 2022
International audienceAdenomatous polyposis coli (APC) is a tumor suppressor whose mutations underlie familial adenomatous polyposis (FAP) and colorectal cancer.
Mastrogiovanni M, Vargas P, Rose T, Cuche C, Esposito E, Juzans M, Laude H, Schneider A, Bernard M, Goyard S, Renaudat C, Ungeheuer MN, Delon J, Alcover A, Di Bartolo V.   +14 more
europepmc   +2 more sources

Gene expression analyses on skin lesions from patients with familial adenomatous polyposis [PDF]

, 2014
Familial adenomatous polyposis coli (FAP) is an autosomal dominant colorectal cancer predisposition syndrome caused by germline mutations in the APC gene.
Stegmann, Danielle Alexandra
core   +1 more source

The adenomatous polyposis coli protein unambiguously localizes to microtubule plus-ends and is involved in establishing parallel arrays of microtubule bundles in highly polarised epithelial cells [PDF]

, 2002
Loss of full-length adenomatous polyposis coli (APC) protein correlates with the development of colon cancers in familial and sporadic cases. In addition to its role in regulating ß-catenin levels in the Wnt signaling pathway, the APC protein is ...
John B. Mackie, Mackie, JB, Nathke, Inke S.; id_orcid, Prescott, AR, Nathke, IS, Mogensen, MM, Mette M. Mogensen, Prescott, Alan R.; id_orcid, Mackie, John B., Tucker, John B., Inke S. Näthke, Näthke, Inke S., John B. Tucker, Mogensen, Mette M., Prescott, Alan R., Alan R. Prescott, Tucker, John Barry   +16 more
core   +1 more source