Results 51 to 60 of about 20,064 (176)

A Novel Germline Mutation of the APC Gene: A Case Report of Familial Adenomatous Polyposis Requiring Repeated Endoscopic Resections for Gastroduodenal Polyps

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2016
Familial adenomatous polyposis (FAP) is a precancerous clinical entity, which is characterized by the development of numerous adenomatous polyps throughout the colon and rectum.
Jun Hui Lee, Joon Weon Jang, Byung-Wook Kim, Eun Su Park, Sang Yong Kim   +4 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, Volume 20, Issue 8, Page 2008-2022, August 2026.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Intramucosal Colon Cancer Developing in an Inverted Hyperplastic Polyp

Gut and Liver, 2013
Attenuated familial adenomatous polyposis (AFAP) is a variant of familial adenomatous polyposis with fewer than one hundred colorectal polyps and a later age of onset of the cancer. Here, we report two cases of AFAP within family members.
doaj   +1 more source

MicroRNAs in Spinal Cord Injury: Molecular and Translational Insights

Brain and Behavior, Volume 16, Issue 8, August 2026.
MicroRNAs (miRNAs) modulate secondary injury cascades following spinal cord injury (SCI), including inflammation, oxidative stress, apoptosis, and demyelination. Key miRNAs such as miR‐21, miR‐124, miR‐219, and miR‐223 exert neuroprotective effects by regulating astrocytic response, axon regeneration, and remyelination.
Seyyedeh Fahimeh Talebi, Hossein Kalarestaghi, Ehsan Sheikh Hesabi, Saeed Vafaei‐Nezhad   +3 more
wiley   +1 more source

Obstructive Pyelonephritis Secondary to Ureteral Compression by an Intra‐Abdominal Desmoid Tumor in Familial Adenomatous Polyposis: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT In patients with familial adenomatous polyposis, intra‐abdominal desmoid tumors should be recognized as a rare but important cause of ureteral obstruction and obstructive pyelonephritis. Prompt cross‐sectional imaging, early recognition, and multidisciplinary management are essential for preserving renal function, treating infection, and ...
Alireza Mehrban, Mehdi Karimi, Mohammad Taghi Hamidian, Mahdi Masoumi, Elahe Tari Najarkolaei, Abdolreza Babamahmoodi   +5 more
wiley   +1 more source

A Novel Germline Mutation in Exon 15 of the APC Gene in Attenuated Familial Adenomatous Polyposis: A Report of Two Cases

Gut and Liver, 2013
Attenuated familial adenomatous polyposis (AFAP) is a variant of familial adenomatous polyposis with fewer than one hundred colorectal polyps and a later age of onset of the cancer. Here, we report two cases of AFAP within family members.
doaj   +1 more source

Smoker's Lungs: Quo Vadis? Exploring the Shared and Individual Smoking‐Related Molecular Pathways of Emphysema, Carcinoma, and Fibrosis – An Illustrative Review

Thoracic Cancer, Volume 17, Issue 16, August 2026.
Cigarette smoking is related to chronic epithelial injury, which represents a central initiating event in smoking‐related lung diseases: NSCLC (non‐small cell lung cancer), IPF (idiopathic pulmonary fibrosis), and emphysema. Altered lung biology and shared molecular pathways contribute to their pathogenesis.
Lovorka Grgurević, Stela Hrkač, Ruđer Novak, Grgur Salai, Joško Mitrović, Tomo Svaguša   +5 more
wiley   +1 more source

AP‐1B Controls Several Levels of Cell Proliferation and Differentiation in Mouse Enteroids

Biology of the Cell, Volume 118, Issue 8, August 2026.
We show that in mouse intestinal organoids, AP‐1B is implicated in apical polarity, differentiation in the secretory lineage and proliferation. In particular, we propose that proliferation is controlled by AP‐1B via the mTOR and YAP pathways. Arrows show the functional links that were elucidated in this study, and dotted lines show putative downstream ...
Maela Duclos, Anne Bourdais, Ophélie Nicolle, Alexandre Helpiquet, Grégoire Michaux, Aurélien Bidaud‐Meynard   +5 more
wiley   +1 more source

The fluctuation of APC gene in WNT signaling with adenine deletion of adenomatous polyposis coli, is associated in colorectal cancer

Journal of Coloproctology, 2020
Colorectal cancer is one of the most important malignancies in the classification of gastrointestinal cancers. One of the predisposing factors at molecular level for this cancer is via WNT signaling which is associated with the vast numbers of different ...
Seyedeh Elham Norollahi, Seyed Mohammad Taghi Hamidian, Zeynab Khazaee Kohpar, Rezvan Azadi, Pooya Rostami, Sogand Vahidi, Sahar Ghazanfari, Farnaz Azar Shabe, Roya Khaksar, Ali Akbar Samadani   +9 more
doaj   +1 more source

Olfactory Ensheathing Cell Transplantation Combined With Electrical Epidural Stimulation as a Long‐Term Treatment for Severe Spinal Cord Injury in Female Fischer 344 Rats

European Journal of Neuroscience, Volume 64, Issue 4, August 2026.
This study combined two promising therapies, olfactory ensheathing cell (OEC) transplantation and electrical epidural stimulation, to help reestablish circuit connectivity following a complete, midthoracic spinal cord transection in inbred Fischer 344 rats (A, B).
Kaitlin L. Ingraham Dixie, Alexa M. Tierno, Michael A. Thornton, Mahlet A. Mekonnen, Erica A. Dale, Hui Zhong, V. Reggie Edgerton, Patricia E. Phelps   +7 more
wiley   +1 more source