Results 101 to 110 of about 486,199 (215)

Proteomic analysis of synergetic neuroprotective effect of adenosine, thiamine, niacin and cyanocobalamin in pathophysiology of diabetic polyneuropathy

Фармакоэкономика
Background. Neurotransmitter adenosine and B-group vitamins have neuroprotective, remyelinizing and anti-neuroinflammatory properties. Despite the studies of these molecules for decades, the molecular mechanisms of their synergistic effect on ...
O. A. Gromova, I. Yu. Torshin, A. G. Moiseenok   +2 more
doaj   +1 more source

Synthetic Small-Molecule Ligands Targeted to Adenosine Receptors: Is There Potential Towards Ischemic Heart Disease?

Cells
Ischemic heart disease (IHD) represents a leading cause of global morbidity and mortality. Despite significant advances in treatment achieved over recent decades, as well as various therapeutic strategies available to manage IHD progression currently ...
Qi Xu, Yaw Nana Opoku, Kalwant S. Authi, Agostino Cilibrizzi   +3 more
doaj   +1 more source

Kinetic studeis of human spleen adenosine deaminases

, 1978
The hydrolysis of adenosine, 2-deoxyadenosine and 6-chloropurine riboside by adenosine deaminase preparations from human spleen has been investigated, and Km and Vm values have been determined.
Creazzola, Maria A.
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Intracoronary Versus Intravenous Adenosine-Induced Maximal Coronary Hyperemia for Fractional Flow Reserve Measurements

, 2014
Background Maximal hyperemia is the critical prerequisite for fractional flow reserve (FFR) assessment. Despite intravenous (IV) adenosine currently being the recommended approach, intracoronary (IC) administration of adenosine constitutes a valuable ...
Ahmed Khashaba, Azza Omran, Ayman Mortada   +2 more
core   +1 more source

PHOSPHONIC ACID ANALOGS OF ADENOSINE-DIPHOSPHATE AND ADENOSINE-TRIPHOSPHATE.

, 1963
PHOSPHONIC ACID ANALOGS OF ADENOSINE-DIPHOSPHATE AND ADENOSINE ...
ALBERT BABA. DANIELZADEH (7953785)
core   +2 more sources

A2A adenosine receptor-mediated increase in coronary flow in hyperlipidemic APOE–knockout mice

, 2011
Bunyen Teng, S Jamal MustafaDepartment of Physiology and Pharmacology and Center for Cardiovascular and Respiratory Sciences, West Virginia University, Morgantown, WV, USAAbstract: Adenosine-induced coronary vasodilation is predominantly A2A adenosine ...
Mustafa SJ, Teng B
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Adenosine-Dependent Activation Mechanism of Prodrugs Targeting an Aminoacyl-tRNA Synthetase

Prodrugs have little or no pharmacological activity and are converted to active drugs in the body by enzymes, metabolic reactions, or through human-controlled actions.
Emeline Mestdach (14328662), Malene Ringkjøbing Jensen (204257), Guillaume Hoffmann (1883002), Loïc Salmon (1510300), Madalen Le Gorrec (14328659), Andrés Palencia (2734129), Stephen Cusack (134664)   +6 more
core   +1 more source

A comparative study of the interaction between the conversion factor from human tissues with the small forms of adenosine deaminase from various organisms

, 1981
Two molecular forms of adenosine deaminase have been isolated from bovine livers. These two forms were found to be interconvertible. Adenosine deaminase extracted from human tissues exhibited similar properties as well.
Puttaswamy, Shashi
core  

CD73: A Promising Biomarker in Cancer Patients

Frontiers in Pharmacology, 2020
Roberta Turiello, Aldo Pinto, Silvana Morello   +2 more
doaj   +1 more source

Role of CD73/adenosine/A2A pathway in the modulation of inflammatory processes

, 2017
Manipulation of the course or of the extension of an inflammatory reaction may include the effort not only to inhibit pro-inflammatory pathways but also through an approach able to enhance endogenous anti-inflammatory processes.
Elisabetta Caiazzo, Pellegrino Lippiello, Carla Cicala, Armando Ialenti   +3 more
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