Results 81 to 90 of about 486,199 (215)

Caffeine Controls Glutamatergic Synaptic Transmission and Pyramidal Neuron Excitability in Human Neocortex

Frontiers in Pharmacology, 2018
Caffeine is the most widely used psychoactive drug, bolstering attention and normalizing mood and cognition, all functions involving cerebral cortical circuits.
Amber Kerkhofs, Amber Kerkhofs, Ana C. Xavier, Beatriz S. da Silva, Paula M. Canas, Sander Idema, Johannes C. Baayen, Samira G. Ferreira, Rodrigo A. Cunha, Rodrigo A. Cunha, Huibert D. Mansvelder   +10 more
doaj   +1 more source

Development of adenosine signalling in the cerebellum [PDF]

The release and clearance of adenosine are reasonably well-documented in the mature CNS but relatively little is known about how adenosine signalling changes during postnatal development.
Atterbury, Alison
core  

Adenosine Receptors and Reperfusion Injury of the Heart

, 2009
Adenosine, a catabolite of ATP, exerts numerous effects in the heart, including modulation of the cardiac response to stress, such as occurs during myocardial ischemia and reperfusion.
Lasley, RD, Headrick, JP, John P. Headrick, Robert D. Lasley   +3 more
core   +1 more source

Cytokine-Induced Killer Cells Express CD39, CD38, CD203a, CD73 Ectoenzymes and P1 Adenosinergic Receptors

Frontiers in Pharmacology, 2018
Cytokine-induced killer (CIK) cells, a heterogeneous T cell population obtained by in vitro differentiation of peripheral blood mononuclear cells (PBMC), represent a promising immunological approach in cancer.
Alberto L. Horenstein, Antonella Chillemi, Roberta Zini, Valeria Quarona, Nicoletta Bianchi, Rossella Manfredini, Roberto Gambari, Fabio Malavasi, Davide Ferrari   +8 more
doaj   +1 more source

MALAT1’s m6A Modification by METTL3 Promotes Pyroptosis and Inflammation in Sepsis-Induced Acute Kidney Injury in Mice

Journal of Inflammation Research
Pengwei Guo,1,* Gao Deng,1,* Lingling Li,1 Haidong Wei,1 Yunxia Gong,1 Yanhong Tan,1 Yanfei Ma2 1Department of Nephrology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise City, Guangxi Zhuang Autonomous Region,
Guo P, Deng G, Li L, Wei H, Gong Y, Tan Y, Ma Y   +6 more
doaj  

Models for the PET quantitative imaging of the adenosine receptor radioligand [11C] SCH442416 in humans [PDF]

, 2010
Positron Emission Tomography is an important imaging technique, that enables regional function to be assayed in a fully quantitative and noninvasive manner. It is based on the use of radioactive tracers: [11C]SCH442416, which is the compound of interest
Boscolo Galazzo, Ilaria
core  

Adenosine regulation of the immune system

, 2018
Adenosine is an endogenous nucleoside, released into the extracellular space in response to metabolic stress and cell damage and critically involved in the maintenance of tissue integrity by modulation of the immune system.
Luca Antonioli, Matteo Fornai, Antonioli, Luca, György Haskó, Fornai, Matteo, Blandizzi, Corrado, Corrado Blandizzi, Haskó, György   +7 more
core   +1 more source

Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from northwestern Uganda following melarsoprol withdrawal [PDF]

, 2009
Human African trypanosomiasis (HAT) manifests as a chronic infection caused by <i>Trypanosoma brucei gambiense</i>, or as a more acute form due to <i>T. b. rhodesiense</i>.
Barbara Nerima, Pascal Mäser, Nerima, B., Barrett, M.P., Nerima, Barbara, de Koning Harry P., Matovu, E., Kazibwe, Anne J., Anne J N Kazibwe, Kazibwe Anne J. N., Enock Matovu, Kazibwe, A.J.N., Mäser, Pascal, De Koning, H.P., Matovu Enock, Harry P de Koning, Barrett Michael P., de Koning, Harry P., Barrett, Michael P., Michael P Barrett, Mäser, P., Mäser Pascal, Matovu, Enock, Nerima Barbara, Kazibwe, Anne J. N.   +24 more
core   +1 more source

Editorial: Adenosine pathways in cancer immunity and immunotherapy

Frontiers in Immunology, 2023
Junjiang Fu, Luca Antonioli, Ali H. El-Far   +2 more
doaj   +1 more source

Unmasking Adenosine: The Purinergic Signalling Molecule Critical to Arrhythmia Pathophysiology and Management [PDF]

, 2019
Adenosine was identified in 1929 and immediately recognised as having a potential role in therapy for arrhythmia because of its negative chronotropic and dromotropic effects.
Matthews, Gareth D.K., Gareth DK Matthews, Andrew A Grace, Grace, Andrew A.   +3 more
core   +1 more source