Results 161 to 170 of about 617,017 (357)

Correction: Case Report: Contrast adenosine stress echocardiography revealing microvascular dysfunction in cardiac AL amyloidosis. [PDF]

Front Cardiovasc Med
Dai Y, Deng Y, Lin N, Che F, Li C, Yin L.   +5 more
europepmc   +1 more source

An Open‐Source Pipeline for Calcium Imaging and All‐Optical Physiology in Human Stem Cell‐Derived Neurons

Advanced Science, EarlyView.
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber, Federico M. Gasparoli, Ziqin Yang, Nicole A. Teaney, Rachel Hobson, Lahin Lalani, Gayathri Srinivasan, Dosh Whye, Ranit Karmakar, Elizabeth D. Buttermore, Kellen D. Winden, Cidi Chen, Mustafa Sahin   +12 more
wiley   +1 more source

<i>In Vitro</i> Evolution of the Adenosine A_2A Receptor Based on an Antagonist Binding Using a Ribosome Display. [PDF]

J Am Chem Soc
Fukasawa G, Matsuoka Y, Tran DP, Nishigaki H, Fukunaga K, Watanabe T, Doura T, Terasaka N, Kagawa A, Murata T, Kitao A, Kiyonaka S, Matsuura T.   +12 more
europepmc   +1 more source

Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy

Journal of Clinical Investigation, 2017
P. Beavis, M. Henderson, Lauren Giuffrida, J. Mills, K. Sek, R. Cross, A. Davenport, Liza B. John, Sherly Mardiana, C. Slaney, R. Johnstone, J. Trapani, J. Stagg, S. Loi, Lev M. Kats, D. Gyorki, M. Kershaw, P. Darcy   +17 more
semanticscholar   +1 more source

ETV4 Promotes Colorectal Cancer Progression by Reprogramming Asparagine Metabolism to Remodel the Stromal Microenvironment

Advanced Science, EarlyView.
ETV4 coordinates a dual transcriptional program by upregulating MET and asparagine synthetase (ASNS). The resulting asparagine (Asn) secretion acts as a metabolic signal, reprogramming hepatic stellate cells (HSCs) and primary cancer‐associated fibroblasts (CAFs) toward an inflammatory phenotype. These activated stromal cells release HGF to sustain the
Dujiang Fu, Meijia Zhang, Maoping Cai, Miao Wang, Ziao Huang, Zesheng Lin, Yixin Liu, Wang Qian, Guopeng Chen, Yuxing Liang, Dongyi Wei, Jing xie, Picheng Yan, Yuanyuan Qu, Yongchang Wei   +14 more
wiley   +1 more source

Remote control of movement disorders using a photoactive adenosine A2A receptor antagonist

, 2018
Jaume Taura, Ernest G. Nolen, Gisela Cabré, Jordi Hernando, Lucia Squarcialupi, Marc López‐Cano, Kenneth A. Jacobson, Víctor Fernández‐Dueñas, Francisco Ciruela   +8 more
openalex   +2 more sources

Impaired adenosine pathways in HFpEF: insights into cardiorenal alterations and endothelial responses. [PDF]

Front Pharmacol
Riemma MA, Madonna G, Mele E, Conte E, Telesca M, De Palma G, Kutryb-Zając B, Cicala C, Imbrici P, Liantonio A, De Angelis A, Urbanek K, Berrino L, Ialenti A, Cappetta D, Donniacuo M, Caiazzo E.   +16 more
europepmc   +1 more source

Deep Learning‐Powered Scalable Cancer Organ Chip for Cancer Precision Medicine

Advanced Science, EarlyView.
This scalable, low‐cost Organ Chip platform, made via injection molding, uses capillary pinning for hydrogel confinement and supports versatile tissue coculture and robust imaging. Deep learning enables label‐free, sensitive phenotypic analysis.
Yu‐Chieh Yuan, Beibei Xu, Jenna McCormack, XuHai Huang, Jingzhe Ma, Thomas Marshall, Yacong Sun, Hardeep Singh, Alyssa Fanelli, Gauri Kulkarni, Ji Hye Seo, Paige Gilbride, Bing Wei, Bo Wang, Yanyan Liu, Fei Ma, Lin Zhou, Shuyang Wang, Xiaohua Qian, Zhiyong Xie, Polina Golland, Longlong Si, Yu Shrike Zhang, Xin Xie, Haiqing Bai   +24 more
wiley   +1 more source

Pharmacological profile of adenosine A2A receptors in patients with lower extremity peripheral artery disease and associated coronary artery disease: A pilot study

, 2019
Marine Gaudry, Marion Marlinge, Pierre Deharo, Donato Vairo, Sarrah Bottone, Giovanna Mottola, Nathalie Kipson, Christine Criado, Patrick Mace, Mohamed Chefrour, Medhy Benchaabane, Celia Magan, Noemi Gentil, Thomas Cuisset, Philippe Piquet, David Lagier, Emmanuel Fenouillet, Régis Guieu, Franck Paganelli, Jean Ruf   +19 more
openalex   +2 more sources

A2AR as a key target for immune microenvironment remodeling in prostate cancer. [PDF]

Transl Oncol
Yan L, Yang Z, Zhao X, Chen Y, Wang Z.
europepmc   +1 more source