Results 161 to 170 of about 681,334 (361)

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng   +11 more
wiley   +1 more source

Purinergic Receptors in Adipose Tissue As Potential Targets in Metabolic Disorders

open access: yesFrontiers in Pharmacology, 2017
Extracellular nucleosides and nucleotides, such as adenosine and adenosine triphosphate (ATP), are involved in many physiological and pathological processes in adipose tissue (AT).
Marco Tozzi, Ivana Novak
doaj   +1 more source

Accurate Transcription Factor Activity Inference to Decipher Cell Identity from Single‐Cell Transcriptomic Data with MetaTF

open access: yesAdvanced Science, EarlyView.
MetaTF is a new computational framework that uses single‐cell RNA sequencing (scRNA‐seq) data to infer transcription factor activity with the aim to help in deciphering cells identity starting from a heterogeneous population, and apply it to characterize mouse hematopoietic stem cells and breast cancer epithelial cells, thus identifying a novel subset ...
Yongfei Hu   +15 more
wiley   +1 more source

Thesis: The Effects of Hypoxia, Metabolic Restriction and Magnetic Fields on Chromosome Instability and Karyotype Contraction in Cancer Cell Lines [PDF]

open access: yesarXiv, 2014
Background: Biological effects of extra-low-frequency (ELF) magnetic fields (MFs) have lacked a credible mechanism of interaction between MFs and living material. Objectives: To examine the effect of ELF-MFs on cancer cells. Methods: Five cancer cell lines were exposed to ELF-MFs within the range of 0.025-5 microTesla, and the cells were examined for ...
arxiv  

Advances in Electrical Materials for Bone and Cartilage Regeneration: Developments, Challenges, and Perspectives

open access: yesAdvanced Science, EarlyView.
This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao   +4 more
wiley   +1 more source

Targeting Purinergic Signaling in the Dynamics of Disease Progression in Sepsis

open access: yesFrontiers in Pharmacology, 2021
Raíssa Leite-Aguiar   +3 more
doaj   +1 more source

On the Dephosphorylation and Deamination of Adenosine Triphosphate by Actomyosin Gel. [PDF]

open access: bronze, 1954
Adam Deutsch   +3 more
openalex   +1 more source

Inhibition of RACK1‐Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, EarlyView.
Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui   +17 more
wiley   +1 more source

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