Results 251 to 260 of about 892,163 (354)

Role of the stage-regulated nucleoside transporter TbNT10 in differentiation and adenosine uptake in Trypanosoma brucei [PDF]

, 2007
Al-Salabi, Burchmore, Burkard, Carter, Christina Kunz Renggli, de Koning, de Koning, de Koning, Delauw, Domenicali Pfister, Flück, Gabriela Burkard, Geiser, Hammond, Iris Spoerri, Isabel Roditi, Keith Matthews, Le Ray, Liniger, Mäser, Ruth Chadwick, Sanchez, Sanchez, Vassella, Vassella, Vickerman   +25 more
core   +2 more sources

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Cardiomyocyte-Specific Deletion of Sirtuin 5 Accelerates the Development of Heart Failure Upon Dysregulating Purine Metabolism. [PDF]

Acta Physiol (Oxf)
Byrne NJ, Koentges C, Pfeil K, Lueg JC, Bakshi S, Tarkhnishvili A, Vosko I, Gollmer J, Birkle LC, Rathner T, Birkle S, Tang S, Rau C, Hoffmann MM, Odening KE, Barnes S, Wilson LS, Ljubojevic-Holzer S, Wallner M, von Lewinski D, Rainer P, Sedej S, Sourij H, Bode C, Wende AR, Zirlik A, Bugger H.   +26 more
europepmc   +1 more source

Nanoparticle‐Modified Nanofibers Induce Ferroptosis and Stimulate Antitumor Immunity for Melanoma Therapy

Advanced Science, EarlyView.
This study presents a nanoparticle‐embedded nanofiber (5F/STFM/R‐ES) to inhibit melanoma growth and reduce the risk of metastasis and recurrence. The drug delivery system induces ferroptosis and potentiates immunotherapy through resiquimod (R848) and Fe/Mn‐based metal‐polyphenol networks (TFM).
Mingyang Li, Rongrong Li, Baotong Xu, Yuhan Lian, Chenyu Yang, Jingwen Li, Junhao Liang, Linhan Ding, Dongsheng Zhang, Jing Guo, Xiao Fu   +10 more
wiley   +1 more source

Protection From Demyelination by the Novel Adenosine Dual A_2A/A_2B Receptor Antagonist P626 in EAE and Cultured Oligodendrocyte Precursor Cells. [PDF]

J Cell Mol Med
Morozzi M, Cherchi F, Sasia C, Frulloni L, Videtta G, Venturini M, Catarzi D, Varano F, Calenda S, Ceni C, Vagnoni G, Colotta V, Coppi E, Pugliese AM, Galeotti N.   +14 more
europepmc   +1 more source

A GLUTAMATE CYSTEINE LIGASE Gene StGSH1 Regulated by StERF10 Enhanced Glutathione Accumulation and Adaptation to Low Phosphorus Stress in Potato

Advanced Science, EarlyView.
The StERF10‐StGSH1 module coordinates glutathione (GSH) biosynthesis under low‐phosphorus stress. The low‐phosphate‐induced AP2/ERF transcription factor StERF10 directly activates the transcription of StGSH1 and enhances GSH accumulation. Consequently, GSH scavenges reactive oxygen species and provides sulfur for sulfolipid synthesis, facilitating the ...
Xiaocheng Tian, Mingjun Li, Xiaojia Huang, Markus Wirtz, Xiaohui Zheng, Shilong Fan, Jiang Tian, Shaoqun Liu, Zhonghua Liu, Hongbo Zhao   +9 more
wiley   +1 more source

Mutant adenosine deaminase 2 in a polyarteritis nodosa vasculopathy.

New England Journal of Medicine, 2014
Paulina Navon Elkan, S. Pierce, R. Segel, T. Walsh, J. Barash, S. Padeh, A. Zlotogorski, Y. Berkun, Joseph J Press, M. Mukamel, I. Voth, P. Hashkes, L. Harel, V. Hoffer, E. Ling, F. Yalçınkaya, O. Kasapcopur, Ming K. Lee, R. Klevit, P. Renbaum, A. Weinberg-Shukron, E. Şener, B. Schormair, S. Zeligson, D. Marek‐Yagel, T. Strom, M. Shohat, A. Singer, A. Rubinow, E. Pras, J. Winkelmann, M. Tekin, Y. Anikster, M. King, E. Levy-Lahad   +34 more
semanticscholar   +1 more source

Adenosine metabolic clearance maintains liver homeostasis by licensing arginine methylation of RIPK1. [PDF]

J Exp Med
Liu R, Wang G, Jiang Z, Zou T, Wang C, Wang W, Cai M, Zhang S, Wang G, Cao H, Zhang D, Wang X, Deng S, Li T, Gu J.   +14 more
europepmc   +1 more source

Regulation of Adenosine 3′:5′-Cyclic Monophosphate Concentration in Cultured Human Astrocytoma Cells by Catecholamines and Histamine

, 1971
Richard B. Clark, John P. Perkins
openalex   +2 more sources

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source