Results 251 to 260 of about 712,877 (361)

Mendelian randomisation and single-cell transcriptomic analyses reveal serotonin promotes multiple sclerosis progression by suppressing adenosine deaminase activity. [PDF]

BMJ Open
Huang L, Shi J, Li H, Lin Q.
europepmc   +1 more source

Light-dependent Adenosine Triphosphatase in Chloroplasts

, 1962
Mordhay Avron
openalex   +1 more source

AI‐Driven De Novo Design of Ultra Long‐Acting GLP‐1 Receptor Agonists

Advanced Science, EarlyView.
De novo GLP‐1RAs can be computationally designed to exhibit extended half‐life and superior efficacy compared to Semaglutide. Abstract Peptide drugs have revolutionized modern therapeutics, offering novel treatment avenues for various diseases. Nevertheless, low design efficacy, time consumption, and high cost still hinder peptide drug design and ...
Ting Wei, Jiating Ma, Xiaochen Cui, Jiahui Lin, Zhuoqi Zheng, Liu Cheng, Taiying Cui, Xiaoqian Lin, Junjie Zhu, Xuyang Ran, Xiaokun Hong, Luke Johnston, Zhangsheng Yu, Haifeng Chen   +13 more
wiley   +1 more source

Structural Simplification from Tricyclic to Bicyclic Scaffolds: A Long-Term Investigation in the Field of Adenosine Receptor Antagonists. [PDF]

Cells
Ceni C, Calenda S, Vagnoni G, Catarzi D, Varano F, Colotta V.   +5 more
europepmc   +1 more source

Adenosine Triphosphate Conservation in Metabolic Regulation

, 1967
Daniel Atkinson, Gordon M. Walton
openalex   +1 more source

Cascade‐Targeted Nanoparticles for Enhanced Gemcitabine Delivery and Adenosine Metabolism Modulation to Overcome Treatment Resistance in Pancreatic Cancer

Advanced Science, EarlyView.
The aberrant adenosine metabolism leads to chemoresistance and immunosuppressive microenvironment. A versatile albumin‐polyplexes conjugated nanoparticle B‐PDEA@CPA is prepare for the codelivery of gemcitabine and siCD39. The nanoparticle releases gemcitabine‐loaded albumin upon microenvironment to achieve promoted penetration and cellular uptake ...
Hongrui Fan, Hongyi Chen, Haolin Song, Chufeng Li, Yu Wang, Zhenhao Zhao, Qin Guo, Xuwen Li, Mingxuan Liu, Tao Sun, Chen Jiang   +10 more
wiley   +1 more source

Adenosine deaminase in pleural effusion: Bridging diagnosis and the pathophysiology of inflammation. [PDF]

World J Clin Cases
Shi DD, Tian J, Ding J.
europepmc   +1 more source

Adenosine 3‘, 5‘-Monophosphate in Biological Materials

, 1965
R.W. Butcher, Ren-jye Ho, H. C. Meng, Earl W. Sutherland   +3 more
openalex   +1 more source

A Lipid with Lewis Pair‐Mediated Targeting and Multiple Stimuli‐Responsive Delivery of Antibiotics for Bacterial Infections

Advanced Science, EarlyView.
Lewis pair‐integrated lipids (Lp‐lipids), combining targeted delivery and stimuli‐responsive are developed for antibiotic delivery. These lipids form nanoparticles that bind biofilms via boronate ester bonds and respond to acidic pH, H2O2, and ATP, enabling controlled drug release.
Xiaojian Yan, Lei Hua, Hongping Wan, Yong Liu, Tao Jin, Yicen Ge, Michael R Hamblin, Mahdi Karimi, Xinghong Zhao, Yan Hu, Linqi Shi, Yuanfeng Li   +11 more
wiley   +1 more source