Results 251 to 260 of about 617,017 (357)

Blockade of Adenosine A2A and ATP P2Y1 Receptors Prevents ILIB Associated Neuronal Toxicity

, 2009
Cunha Rodrigo
openalex   +1 more source

Unexpected complication following total thyroidectomy: A case report and brief review of the literature. [PDF]

Med Int (Lond)
Qadir AN, Ahmed SF, Ahmed FJ, Raheem BJ, Saeed TO, Hussein AO, Amin ZH, Qadir DT, Abdalla BA, Kakamad FH.   +9 more
europepmc   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

Advanced Science, EarlyView.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty, Kamal el Battioui, Dániel Molnár, Bálint Jezsó, Lejla Daruka, Tasvilla Sonallya, Tünde Juhász, Rita Hirmondó, Imola Cs. Szigyártó, Loránd Románszki, Natália Tőkési, Daniel Pinkas, Eszter Házy, Olivér Pavela, Andrea Bodor, Zoltán Varga, István Mándity, Mihály Kovács, Csaba Pál, Kata Horváti, Judit Tóth, Tamás Beke‐Somfai   +21 more
wiley   +1 more source

ADA1-Driven Metabolic Refueling Enhances CAR T Cell Therapy for Solid Tumors. [PDF]

Cancers (Basel)
Song AW, Song X.
europepmc   +1 more source

A “Hot Spring” Mimetic Aerogel Loaded with Multiple Amino Acids Modulates the Chronic Inflammatory Microenvironment Through Metabolic Reprogramming

Advanced Science, EarlyView.
The SrCuSi4O₁₀ bioceramic particles mimic the effects of hot spring therapy by increasing the local wound temperature, which enhances the absorption of amino acids and stimulates cell metabolism. The amino acid uptake supports cellular glutathione redox reactions, helping to mitigate oxidative stress.
Bo Li, Dandan Jin, Fei Li, Jianliang Shen, Jiang Chang, Chen Yang, Shixuan Chen, Yi Zhang   +7 more
wiley   +1 more source

Ecto-5'-nucleotidase/CD73 reduces COX-2 expression in activated macrophages. [PDF]

Sci Rep
Rahman MM, Sircar A, Lakhina S, Kumar P, Gupta RD, Akundi RS.   +5 more
europepmc   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

Role of Adenosine in Renal Protection Induced by a Brief Episode of Ischemic Preconditioning in Rats

, 2001
Haruko Sugino, Hideyo Shimada, Kanji Tsuchimoto   +2 more
openalex   +1 more source

CD73 Blockade Aggravate Dextran-Sodium-Sulfate-Induced Colitis via Down Regulating Inosine. [PDF]

J Inflamm Res
Yang L, Wang X, Lin F, Liu C, Liu Y, Deng QC, Gao ZW.   +6 more
europepmc   +1 more source