Results 191 to 200 of about 124,204 (359)

Reduction of postischemic leukocyte-endothelium interaction by adenosine via A\(_2\) receptor [PDF]

, 1992
The adhesion of leukocytes to the endothelium of postcapillary venules hallmarks a key event in ischemia-reperfusion injury. Adenosine has been shown to protect from postischemic reperfusion injury, presumably through inhibition of postischemic leukocyte-
Klotz, Karl-Norbert, Lehr, H.-A., Lorenzen, A., Messmer, K., Nolte, D., Zimmer, F.-J.   +5 more
core  

Adenosine A1 Receptor Agonist (R-PIA) before Pilocarpine Modulates Pro- and Anti-Apoptotic Factors in an Animal Model of Epilepsy. [PDF]

Pharmaceuticals (Basel), 2021
Persike DS, Puccinelli RPA, Fernandes MJDS.   +2 more
europepmc   +1 more source

Effects of Repeated Administration of KW-3902, a Novel Adenosine A1-Receptor Antagonist, on Its Pharmacological Actions

, 1993
Hideaki Kusaka, Akira Karasawa
openalex   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, Volume 12, Issue 29, August 7, 2025.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

Lung Injury Pathways: Adenosine Receptor 2B Signaling Limits Development of Ischemic Bronchiolitis Obliterans Organizing Pneumonia [PDF]

, 2017
Purpose/Aim of the Study: Adenosine signaling was studied in bronchiolitis obliterans organizing pneumonia (BOOP) resulting from unilateral lung ischemia. Materials and Methods: Ischemia was achieved by either left main pulmonary artery or complete hilar
Auchampach, John, Audi, Said H., Densmore, John C., Dwinell, Melinda R., Geurts, Aron M., Jacobs, Elizabeth R., Jeziorczak, Paul M., Medhora, Meetha, Nayak, Shraddha, Schaid, Terry R.   +9 more
core   +1 more source

Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation. [PDF]

Cell Rep Med
Zhu W, Hong Y, Tong Z, He X, Li Y, Wang H, Gao X, Song P, Zhang X, Wu X, Tan Z, Huang W, Liu Z, Bao Y, Ma J, Zheng N, Xie C, Ke X, Zhou W, Jia W, Li M, Zhong J, Sheng L, Li H.   +23 more
europepmc   +2 more sources

Adenosine A₁ receptor agonism protection mechanism in intestinal ischemia/reperfusion injury via activation of PI3K/Akt signaling. [PDF]

Exp Ther Med, 2023
Xu Q, Mao Z, Yun Y.
europepmc   +1 more source

A1 adenosine receptors of bovine brain couple to guanine nucleotide-binding proteins Gi1, Gi2, and Go.

, 1991
R Munshi, Iok-Hou Pang, Paul C. Sternweis, Joel Linden   +3 more
openalex   +1 more source

Co‐Expression of MHC‐II and ANXA1: Mediators of PD‐1/PD‐L1 Therapy Resistance in Breast Cancer

Cancer Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background Triple‐negative breast cancer (TNBC) presents significant treatment challenges and poor prognosis. While immune checkpoint blockade (ICB) therapy shows promise, patient responses vary widely, highlighting the urgent need for reliable biomarkers to predict efficacy and guide treatment decisions.
Hao Wang, Ji‐Feng Sun, Chen Wang, Zhan‐Sheng Jiang, Zhong‐Sheng Tong   +4 more
wiley   +1 more source

A Chemical Biological Approach to Study G Protein-Coupled Receptors: Labeling the Adenosine A₁ Receptor Using an Electrophilic Covalent Probe. [PDF]

ACS Chem Biol, 2022
Beerkens BLH, Koç Ç, Liu R, Florea BI, Le Dévédec SE, Heitman LH, IJzerman AP, van der Es D.   +7 more
europepmc   +1 more source