Adenosine Deaminase Deficiency – More Than Just an Immunodeficiency
Frontiers in Immunology, 2016 Adenosine deaminase (ADA) deficiency is best known as a form of severe combined immunodeficiency (SCID) that results from mutations in the gene encoding ADA.
K. Whitmore, H. Gaspar
semanticscholar +1 more source
Decoding RNA–Protein Interactions: Methodological Advances and Emerging Challenges
Advanced Genetics, EarlyView.This review provides a comprehensive comparison of RNA‐ and protein‐centric methodologies for investigating RNA–protein interactions, emphasizing their respective advantages, limitations, and suitable applications. It highlights recent technological innovations, outlines strategic method selection criteria, and addresses key challenges.
Wenkai Yi, Jian Yan
wiley +1 more source
Adenosine turnover (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database [PDF]
, 2019 A multifunctional, ubiquitous molecule, adenosine acts at cell-surface G protein-coupled receptors, as well as numerous enzymes, including protein kinases and adenylyl cyclase.
Boison, Detlev
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ATP Hysteresis in Tripartite Synapses [PDF]
arXiv, 2009 Recent experimental studies strongly suggest the influence of glial purinergic transmission in the modulation of synaptic dynamics. By releasing adenosine triphosphate (ATP), which accumulates as adenosine, astrocytes tonically suppressed synaptic transmission. The delayed multi-step feedback of the glial adenosine with the neuron suggest the existence
arxiv
Investigating the role of SARM1 in central nervous system
Ibrain, EarlyView.Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang +4 more
wiley +1 more source
Immunological diagnosis as an adjunctive tool for an early diagnosis of tuberculous meningitis of an immune competent child in a low tuberculosis endemic country: A case report [PDF]
, 2017 Background: Pediatric tuberculous meningitis is a highly morbid, often fatal disease. Its prompt diagnosis and treat - ment saves lives, in fact delays in the initiation of therapy have been associated with high mortality rates. Case presentation:
Ajassa, Camilla +12 more
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Clinical Significance of Serum Adenosine Deaminase Levels in Breast Cancer Patients
Journal of Islamic International Medical College, 2021 Objective: To compare serum adenosine deaminase (ADA) levels in untreated and treated cases of breast cancer patients. Study Design: It was an Analytical, observational study. Place and Duration of study: The study was carried out in the Department
Wajahat Ullah Khan, Amena Rahim, Kenza Mobeen, Muhammad Afzal, Abdul Khaliq Naveed
doaj
A adenosinadesaminase. Uma enzima pluridisciplinar.
Acta Médica Portuguesa, 1991 Adenosine deaminase is an enzyme that actively participates in the metabolism of the adenine nucleotides. It catalyzes the irreversible hydrolytic deamination of deoxyadenosine and adenosine with the production of deoxyinosine and inosine respectively ...
J G da Cunha
doaj +1 more source
Non-specific biological markers as a screening test for diagnostic of extrapulmonary tuberculosis [PDF]
Archives of Biological Sciences, 2012 Serum concentrations of adenosine deaminase were determined in 223 febrile patients. In 62, we discovered extrapulmonary tuberculosis. Serum levels of immunoglobulin G were monitored in 287 febrile patients, and 68 had extra-pulmonary tuberculosis ...
Stevanovic G. +3 more
doaj +1 more source
Direct Growth Graphene on Cu Nanoparticles by Chemical Vapor Deposition as Surface-Enhanced Raman Scattering Substrate for Label-Free Detection of Adenosine [PDF]
arXiv, 2015 We present a graphene/Cu nanoparticle hybrids (G/CuNPs) system as a surface-enhanced Raman scattering (SERS) substrate for adenosine detection. The Cu nanoparticles wrapped around a monolayer graphene shell were directly synthesized on flat quartz by chemical vapor deposition in a mixture of methane and hydrogen.
arxiv