Results 101 to 110 of about 54,436 (239)
MedComm, Volume 7, Issue 3, March 2026.Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia +4 more
wiley +1 more source
The Turkish Journal of Pediatrics, 2019 Deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessive autoinflammatory disorder caused by mutations in CECR1 (cat eye syndrome chromosome region, canditate 1) gene, which encodes the enzyme adenosine deaminase 2 necessary for endothelial
Mustafa Çakan +7 more
doaj +1 more source
ADENOSINEDEAMINASE ACTIVITY IN CEREBROSPINAL FLUID FOR DIAGNOSIS OF TUBERCULOSIS MENINGITIS [PDF]
Background:Tuberculous meningitis remains a serious clinical problem. Missed diagnosis and delayed treatment result in significant morbidity and mortality.
Harish Bhat +5 more
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The role of the neuromodulator adenosine in alcohols actions. [PDF]
, 1997 The interaction between the neuromodulator adenosine and adenosine receptors on the surface of neurons modifies the neurons responses to neurotransmitters.
Diamond, Ivan, Dohrman, D, Gordon, A
core
CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling
Med Research, Volume 2, Issue 1, Page 106-129, March 2026.CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li +8 more
wiley +1 more source
Adenosine Deaminase Activity in COPD Patients and Healthy Subjects
Iranian Journal of Allergy, Asthma and Immunology, 2010 Chronic obstructive pulmonary disease (COPD) has been defined by the Global Initiative for Chronic Obstructive Lung Disease (GOLD), as a disease state characterized by airflow limitation which is not fully reversible.
Mohammad Taghi Goodarzi +4 more
doaj
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.ABSTRACT Fludarabine (Flu), administered as a prodrug Flu monophosphate, is a lymphodepleting agent used prior to hematopoietic stem cell transplantation (HSCT) which exhibits substantial pharmacokinetics (PK) variability, contributing to suboptimal outcomes.
Mourad Mseddi +9 more
wiley +1 more source
Dasatinib Associated Pleural Complications‐ A Case Series
Respirology Case Reports, Volume 14, Issue 3, March 2026.Dasatinib is an effective therapy for chronic myeloid leukaemia but may lead to pleural complications, including exudative effusions and rare chylothorax. This case series describes four patients who developed pleural effusions after long‐term dasatinib therapy, highlighting successful management through dose reduction or TKI switching.
Vishnu Vazhoor +4 more
wiley +1 more source
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
Small, Volume 22, Issue 16, 17 March 2026.The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa +4 more
wiley +1 more source
The Clinical Respiratory Journal, Volume 20, Issue 3, March 2026.This study identifies D‐dimer as a key mediator between lymphocyte depletion and pulmonary tuberculosis dissemination. Our findings reveal that reduced lymphocyte counts increase dissemination risk partly by elevating D‐dimer levels, suggesting a critical link between immune deficiency and coagulopathy.
Yujun Lin +4 more
wiley +1 more source