Results 101 to 110 of about 62,280 (291)
Molecular evidence of adenosine deaminase linking adenosine A2A receptor and CD26 proteins [PDF]
Adenosine is an endogenous purine nucleoside that acts in all living systems as a homeostatic network regulator through many pathways, which are adenosine receptor (AR)-dependent and -independent. From a metabolic point of view, adenosine deaminase (ADA)
Akiyama +161 more
core +1 more source
On the Origin of Substrate Specificity of Enzymes from the Amidohydrolase Superfamily
Comprehensive analyses of two enzyme classes from the amidohydrolase superfamily (AHS) revealed that catalysis proceeds either via 1,4 or 1,6 nucleophilic conjugate addition and that this property defines substrate specificity. Moreover, although all substrates and products are entirely achiral, this mechanistic difference results in an inverted ...
Lukas Drexler +3 more
wiley +1 more source
ADENOSINEDEAMINASE ACTIVITY IN CEREBROSPINAL FLUID FOR DIAGNOSIS OF TUBERCULOSIS MENINGITIS [PDF]
Background:Tuberculous meningitis remains a serious clinical problem. Missed diagnosis and delayed treatment result in significant morbidity and mortality.
Harish Bhat +5 more
core
Metal Nanoclusters for Cancer Imaging and Treatment
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu +5 more
wiley +1 more source
Adenosine deaminase (ADA) level in tubercular pleural effusion
Study objective : To study the value of adenosine deaminase level in tuber-cular pleural effusion. Design: A hospital based observational study. Setting : Out and In patients service of department of Tuberculosis & Chest Diseases, MLN Medical ...
Verma S +4 more
doaj
Deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessive autoinflammatory disorder caused by mutations in CECR1 (cat eye syndrome chromosome region, canditate 1) gene, which encodes the enzyme adenosine deaminase 2 necessary for endothelial
Mustafa Çakan +7 more
doaj +1 more source
Anatomical Distribution of Nucleoside System in the Human Brain and Implications for Therapy [PDF]
Nucleosides have a wide range of physiological and pathophysiological roles in the human brain as modulators of a variety of neural functions. For example, adenosine, inosine, guanosine, and uridine participate in the mechanisms underlying memory ...
Dobolyi, Árpád, Kovács, Zsolt
core +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Oxidative Stress and Its Relationship With Adenosine Deaminase Activity in Various Stages of Breast Cancer [PDF]
Mridula Mahajan +4 more
openalex +1 more source

