Results 101 to 110 of about 62,280 (291)

Molecular evidence of adenosine deaminase linking adenosine A2A receptor and CD26 proteins [PDF]

open access: yes, 2018
Adenosine is an endogenous purine nucleoside that acts in all living systems as a homeostatic network regulator through many pathways, which are adenosine receptor (AR)-dependent and -independent. From a metabolic point of view, adenosine deaminase (ADA)
Akiyama   +161 more
core   +1 more source

On the Origin of Substrate Specificity of Enzymes from the Amidohydrolase Superfamily

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 4, 22 January 2026.
Comprehensive analyses of two enzyme classes from the amidohydrolase superfamily (AHS) revealed that catalysis proceeds either via 1,4 or 1,6 nucleophilic conjugate addition and that this property defines substrate specificity. Moreover, although all substrates and products are entirely achiral, this mechanistic difference results in an inverted ...
Lukas Drexler   +3 more
wiley   +1 more source

ADENOSINEDEAMINASE ACTIVITY IN CEREBROSPINAL FLUID FOR DIAGNOSIS OF TUBERCULOSIS MENINGITIS [PDF]

open access: yes
Background:Tuberculous meningitis remains a serious clinical problem. Missed diagnosis and delayed treatment result in significant morbidity and mortality.
Harish Bhat   +5 more
core  

Metal Nanoclusters for Cancer Imaging and Treatment

open access: yesAdvanced Functional Materials, Volume 36, Issue 2, 5 January 2026.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu   +5 more
wiley   +1 more source

Adenosine deaminase (ADA) level in tubercular pleural effusion

open access: yesLung India, 2008
Study objective : To study the value of adenosine deaminase level in tuber-cular pleural effusion. Design: A hospital based observational study. Setting : Out and In patients service of department of Tuberculosis & Chest Diseases, MLN Medical ...
Verma S   +4 more
doaj  

Atypical phenotype of an old disease or typical phenotype of a new disease: deficiency of adenosine deaminase 2

open access: yesThe Turkish Journal of Pediatrics, 2019
Deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessive autoinflammatory disorder caused by mutations in CECR1 (cat eye syndrome chromosome region, canditate 1) gene, which encodes the enzyme adenosine deaminase 2 necessary for endothelial
Mustafa Çakan   +7 more
doaj   +1 more source

Anatomical Distribution of Nucleoside System in the Human Brain and Implications for Therapy [PDF]

open access: yes, 2013
Nucleosides have a wide range of physiological and pathophysiological roles in the human brain as modulators of a variety of neural functions. For example, adenosine, inosine, guanosine, and uridine participate in the mechanisms underlying memory ...
Dobolyi, Árpád, Kovács, Zsolt
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Oxidative Stress and Its Relationship With Adenosine Deaminase Activity in Various Stages of Breast Cancer [PDF]

open access: bronze, 2012
Mridula Mahajan   +4 more
openalex   +1 more source

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