Results 41 to 50 of about 89,334 (262)

Yeast Phosphoramidate-Adenosine Diphosphate Phosphotransferase [PDF]

Journal of Biological Chemistry, 1968
Abstract An enzyme, phosphoramidate-ADP phosphotransferase, has been isolated from dried bakers' yeast. We have previously shown that phosphoramide, N-phosphorylglycine, and N-phosphohistidine can act as phosphate donors. Phosphoiodohistidine was shown also to function as a phosphate donor and the enzyme was stereospecific for the l form of this ...
Henry I. Nakada, Michael J. Dowler
openaire   +2 more sources

The membrane bound N-terminal domain of human adenosine diphosphate ribosylation factor-1 (ARF1) [PDF]

, 2003
The small G protein adenosine diphosphate ribosylation factor-1 (ARF1) is activated by cell membrane binding of a self-folding N-terminal domain. We present a model of the human ARF1 N-terminal peptide in planar lipid bilayers, determined from neutron ...
Amor, Antonny, Bé, Bohm, Bradshaw, Bradshaw, Bradshaw, Brasseur, Darkes, Duff, Franco, Goldberg, Gordeliy, Jacobs, Johnson, Kraulis, Mé, Mayer, Merritt, Roth, Sreerama, Wiener, Wiener   +22 more
core   +1 more source

Purinergic Signaling in Pulmonary Inflammation

Frontiers in Immunology, 2019
Purine nucleotides and nucleosides are at the center of biologic reactions. In particular, adenosine triphosphate (ATP) is the fundamental energy currency of cellular activity and adenosine has been demonstrated to play essential roles in human ...
Thanh-Thuy T. Le, Nathaniel K. Berg, Matthew T. Harting, Xiangyun Li, Xiangyun Li, Holger K. Eltzschig, Xiaoyi Yuan   +6 more
doaj   +1 more source

Type III effector activation via nucleotide binding, phosphorylation, and host target interaction. [PDF]

PLoS Pathogens, 2007
The Pseudomonas syringae type III effector protein avirulence protein B (AvrB) is delivered into plant cells, where it targets the Arabidopsis RIN4 protein (resistance to Pseudomonas maculicula protein 1 [RPM1]-interacting protein).
Darrell Desveaux, Alex U Singer, Ai-Jiuan Wu, Brian C McNulty, Laura Musselwhite, Zachary Nimchuk, John Sondek, Jeffery L Dangl   +7 more
doaj   +1 more source

rLOAD: does sex mediate the effect of acute antiplatelet loading on stroke outcome. [PDF]

, 2014
BackgroundBiologic sex can influence response to pharmacologic therapy. The purpose of this proof-of-concept study was to evaluate the medicating effects of estrogen in the efficacy of acute antiplatelet loading therapy on stroke outcome in the rabbit ...
Compton, M Peggy, Eastwood, Jo-Ann, Gylys, Karen, Meyer, Dawn M, Zivin, Justin A   +4 more
core   +3 more sources

Dynamics of Microtubule Growth and Catastrophe [PDF]

Phys. Rev. E 76, 041907 (2007), 2007
We investigate a simple model of microtubule dynamics in which a microtubule evolves by: (i) attachment of guanosine triphosphate (GTP) to its end at rate lambda, (ii) GTP converting irreversibly to guanosine diphosphate (GDP) at rate 1, and (iii) detachment of GDP from the end of a microtubule at rate mu.
arxiv   +1 more source

TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity

mAbs, 2022
Cluster of differentiation 38 (CD38) is an ecto-enzyme expressed primarily on immune cells that metabolizes nicotinamide adenine dinucleotide (NAD+) to adenosine diphosphate ribose or cyclic ADP-ribose and nicotinamide.
Harshad S. Ugamraj, Kevin Dang, Laure-Hélène Ouisse, Benjamin Buelow, Eduardo N. Chini, Giulia Castello, James Allison, Starlynn C Clarke, Laura M. Davison, Roland Buelow, Rong Deng, Suhasini Iyer, Ute Schellenberger, Sankar N. Manika, Shipra Bijpuria, Astrid Musnier, Anne Poupon, Maria Cristina Cuturi, Wim van Schooten, Pranjali Dalvi   +19 more
doaj   +1 more source

Ecto-5′-nucleotidase and intestinal ion secretion by enteropathogenic Escherichia coli [PDF]

, 2007
Enteropathogenic Escherichia coli (EPEC) triggers a large release of adenosine triphosphate (ATP) from host intestinal cells and the extracellular ATP is broken down to adenosine diphosphate (ADP), AMP, and adenosine.
A Nusrat, A Oganesian, B Kenny, B McNamara, BA McCormick, D Bieber, D Heithoff, DN Gupta, FS Barros, GR Strohmeier, H Zalkin, I Peiffer, Irina Shulgina, J Crane, J Crane, J Crane, J Crane, J Navarro, J Xu, JK Crane, John K. Crane, K Gounaris, K Hoque, K Synnestvedt, M Bradford, M Khan, M Levine, M Levine, ME Penny, MF Bernet-Camard, MT Lehto, N Darmon, O Guckelberger, P Dutta, P Koszalka, R Devinney, R Rothbaum, R Rothbaum, RA Olsson, S Chiang, S Colgan, S Kelleher, S Nash, S Ohkubo, S Sazawal, SJ Elliott, T Knöfel, Tonniele M. Naeher, V Puni, W Deng, Y Fujii, Y-H Tai, Y-S Bae   +52 more
core   +2 more sources

Dynamics of Microtubule Instabilities [PDF]

J. Stat. Mech. (2007) L05004, 2007
We investigate the dynamics of an idealized model of microtubule growth that evolves by: (i) attachment of guanosine triphosphate (GTP) at rate lambda, (ii) conversion of GTP to guanosine diphosphate (GDP) at rate 1, and (iii) detachment of GDP at rate mu. As a function of these rates, a microtubule can grow steadily or its length can fluctuate wildly.
arxiv   +1 more source

The importance of calcium in the regulation of megakaryocyte function

Haematologica, 2014
Platelet release by megakaryocytes is regulated by a concert of environmental and autocrine factors. We previously showed that constitutively released adenosine diphosphate by human megakaryocytes leads to platelet production. Here we show that adenosine
Christian Andrea Di Buduo, Francesco Moccia, Monica Battiston, Luigi De Marco, Mario Mazzucato, Remigio Moratti, Franco Tanzi, Alessandra Balduini   +7 more
doaj   +1 more source