Results 41 to 50 of about 288,808 (285)

Adenosine diphosphate inhibits the serotonin transporter

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1996
Adenosine 5'-diphosphate (ADP) caused rapid and significant reductions in the rates of [3H]serotonin uptake observed for human platelets, human platelet vesicles, and rat brain synaptic vesicles. Estimated Vmax values in platelets (N = 15). platelet vesicles (N = 3), and synaptic vesicles (N = 3) exposed to 100 microM ADP were 42.3 +/- 11.4%, 78.8 ...
William C. Horne   +3 more
openaire   +3 more sources

ADMINISTRATION OF FRUCTOSE 1,6-DIPHOSPHATE DURING EARLY REPERFUSION SIGNIFICANTLY IMPROVES RECOVERY OF CONTRACTILE FUNCTION IN THE POSTISCHEMIC HEART [PDF]

open access: yes, 1998
Objectives: Fructose-1,6-diphosphate is a glycolytic intermediate that has been shown experimentally to cross the cell membrane and lead to increased glycolytic flux.
Cao-Danh, Hung   +7 more
core   +1 more source

Type III effector activation via nucleotide binding, phosphorylation, and host target interaction. [PDF]

open access: yesPLoS Pathogens, 2007
The Pseudomonas syringae type III effector protein avirulence protein B (AvrB) is delivered into plant cells, where it targets the Arabidopsis RIN4 protein (resistance to Pseudomonas maculicula protein 1 [RPM1]-interacting protein).
Darrell Desveaux   +7 more
doaj   +1 more source

Free Adenosine Diphosphate as an Intermediary in the Phosphorylation by Creatine Phosphate of Adenosine Diphosphate Bound to Actin

open access: yesJournal of Biological Chemistry, 1967
Abstract Pretreatment of adenosine diphosphate-G-actin solutions with apyrase results in a marked decrease in their rate of polymerization at 0° induced by KCl, creatine phosphate, and creatine kinase. In contrast, apyrase has no effect on the rate of polymerization of ATP-G-actin.
B. Nagy, J.J. West, John Gergely
openaire   +3 more sources

Purinergic Signaling in Pulmonary Inflammation

open access: yesFrontiers in Immunology, 2019
Purine nucleotides and nucleosides are at the center of biologic reactions. In particular, adenosine triphosphate (ATP) is the fundamental energy currency of cellular activity and adenosine has been demonstrated to play essential roles in human ...
Thanh-Thuy T. Le   +6 more
doaj   +1 more source

ANALYSIS OF THE STATE OF PLATELET AGGREGATION IN PREGNANT WOMEN WITH THROMBOPHILIA AND BURDENED OBSTETRIC HISTORY

open access: yesСхідноукраїнський медичний журнал, 2021
The analysis of platelet aggregation in pregnant women with thrombophilia and burdened obstetric history was performed. It has been determined that the development of adverse effects of pregnancy is significantly influenced by conditions such as ...
Olha I. Zalyubovska   +1 more
doaj   +1 more source

Strategies for the Use of Poly(adenosine diphosphate ribose) Polymerase (PARP) Inhibitors in Cancer Therapy

open access: yesBiomolecules, 2012
Treatments with Poly(adenosine diphosphate ribose) polymerase (PARP) inhibitors have offered patients carrying cancers with mutated BRCA1 or BRCA2 genes a new and in many cases effective option for disease control.
Cecilia E. Ström, T. Helleday
semanticscholar   +1 more source

Phosphoproteins and protein-kinase activity in isolated envelopes of pea (Pisum sativum L.) chloroplasts [PDF]

open access: yes, 1985
A protein kinase was found in envelope membranes of purified pea (Pisum sativum L.) chloroplasts. Separation of the two envelope membranes showed that most of the enzyme activity was localized in the outer envelope.
D.G. Robinson   +17 more
core   +1 more source

TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity

open access: yesmAbs, 2022
Cluster of differentiation 38 (CD38) is an ecto-enzyme expressed primarily on immune cells that metabolizes nicotinamide adenine dinucleotide (NAD+) to adenosine diphosphate ribose or cyclic ADP-ribose and nicotinamide.
Harshad S. Ugamraj   +19 more
doaj   +1 more source

The platelet P2Y₁₂ receptor for adenosine diphosphate: congenital and drug-induced defects.

open access: yesBlood, 2011
P2Y₁₂, the G(i)-coupled platelet receptor for adenosine diphosphate (ADP), plays a central role in platelet function. Patients with congenital P2Y₁₂ defects display a mild to moderate bleeding diathesis, characterized by mucocutaneous bleedings and ...
M. Cattaneo
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy