Results 51 to 60 of about 92,139 (169)

Excited state dynamics in DNA double helices [PDF]

open access: yesarXiv, 2006
Recent ultrafast experiments have implicated that intrachain base-stacking rather than base-pairing mediate the fate and transport of photoexcited species in DNA chains. Here use an $SU(2)\otimes SU(2)$ lattice model which incorporates both intrachain and interchain electronic interactions to study the quantum mechanical evolution of an initial ...
arxiv  

Purinergic signalling: past, present and future [PDF]

open access: yes, 2009
The discovery of non-adrenergic, non-cholinergic neurotransmission in the gut and bladder in the early 1960's is described as well as the identification of adenosine 5'-triphosphate (ATP) as a transmitter in these nerves in the early 1970's.
Burnstock, G
core   +1 more source

Attenuation of ischemic liver injury by prostaglandin E1 analogue, misoprostol, and prostaglandin I2 analogue, OP-41483 [PDF]

open access: yes, 1998
Background: Prostaglandin has been reported to have protective effects against liver injury. Use of this agent in clinical settings, however, is limited because of drugrelated side effects.
Ishizaki, N   +8 more
core   +1 more source

One-pot Enzymatic Synthesis of Deoxy-thymidine-diphosphate (TDP)-2-deoxy-∝-d-glucose Using Phosphomannomutase

open access: yes, 2010
Production of deoxy-thymidine-diphosphate (TDP)-sugars as substrates of glycosyltransferases, has been one of main hurdles for combinatorial antibiotic biosynthesis, which combines sugar moiety with aglycon of various antibiotics. Here, we report the one-
Kang, Young Bok (Abraham)   +10 more
core  

Pump-induced platelet aggregation with subsequent hypotension: Its mechanism and prevention with clopidogrel [PDF]

open access: yes, 2006
ObjectivesUse of extracorporeal circuits in cardiopulmonary bypass and hemodialysis often causes bleeding problems and hypotension. As shown previously, this might be caused by activation of blood platelets due to pumping.
Borgdorff, Piet, Tangelder, Geert Jan
core   +1 more source

Frenkel Exciton Model of Ultrafast Excited State Dynamics in AT DNA Double Helices [PDF]

open access: yesJ. Photochem. and Photobiol. A 190, 328-334 (2007), 2006
Recent ultrafast experiments have implicated intrachain base-stacking rather than base-pairing as the crucial factor in determining the fate and transport of photoexcited species in DNA chains. An important issue that has emerged concerns whether or not a Frenkel excitons is sufficient one needs charge-transfer states to fully account for the dynamics.
arxiv  

Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells [PDF]

open access: yes, 2008
Purinergic signalling is important both in short-term control of vascular tone and in longer-term control of cell proliferation, migration and death involved in vascular remodelling.
Burnstock, G
core  

NMR Dynamics Investigation of Ligand-Induced Changes of Main and Side-Chain Arginine N-H’s in Human Phosphomevalonate Kinase [PDF]

open access: yes, 2010
Phosphomevalonate kinase (PMK) catalyzes phosphoryl transfer from adenosine triphosphate (ATP) to mevalonate 5-phosphate (M5P) on the pathway for synthesizing cholesterol and other isoprenoids.
Cai, Sheng   +4 more
core   +2 more sources

Pilot study of electrochemical reduction of selected nucleotides and double-stranded DNA at pristine micro-/ultrananocrystalline boron-doped diamond electrodes at very negative potentials [PDF]

open access: yes
Pristine polycrystalline boron-doped diamond electrodes (BDDEs) -- microcrystalline (B-MCDE) and ultrananocrystalline (B-UNCDE) were applied for the electrochemical reduction of several selected purine nucleotides -- Guanosine 5'-monophosphate (GMP), 2'-Deoxyguanosine 5'-monophosphate (dGMP), Adenosine 5'-monophosphate (AMP), Adenosine 5'-diphosphate ...
arxiv   +1 more source

Long-term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation and death [PDF]

open access: yes, 2010
The purinergic signalling system, which uses purines and pyrimidines as chemical transmitters, and purinoceptors as effectors, is deeply rooted in evolution and development and is a pivotal factor in cell communication.
A Gartland   +139 more
core   +2 more sources

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