Results 181 to 190 of about 34,973 (226)

Studies on poly (adenosine diphosphate-ribose)

Archives of Biochemistry and Biophysics, 1971
Michiyuki Yamada, Masanao Miwa, Takashi Sugimura   +2 more
semanticscholar   +3 more sources

ADENOSINE DIPHOSPHATE RIBOSE PYROPHOSPHOHYDROLASE IN HUMAN SKIN

The Journal of Dermatology, 1980
ABSTRACTAdenosine diphosphate ribose (ADPR) pyrophosphohydrolase (ADPR‐PPase), which catalyzes the hydrolysis of ADPR to yield adenosine monophosphate (AMP) and ribose‐5′‐phosphate, was assayed in human penile foreskin. Since ADPR is formed from nicotinamide adenine dinucleotide (NAD) by NAD glycohydrolase (NADase), NADase was also assayed in human ...
Y P, Kim, J B, Kahng, J Y, Choi
openaire   +2 more sources

Presence and turnover of adenosine diphosphate ribose in human erythrocytes

Biochemical and Biophysical Research Communications, 1992
ADP-ribose was detected in human red blood cells (RBC) at 0.45 +/- 0.1 microM concentrations. These levels could be estimated after purification of ADP-ribose by means of three sequential HPLC fractionations of RBC extracts. Extraction was performed by sonication of RBC either in trichloroacetic acid, followed by centrifugation, or in carbonate ...
GUIDA, LUCREZIA, ZOCCHI, ELENA, FRANCO L., BENATTI, UMBERTO, DE FLORA, ANTONIO   +4 more
openaire   +3 more sources

Structure of poly(adenosine diphosphate ribose): identification of 2'-[1''-ribosyl-2''-(or 3''-)(1'''-ribosyl)]adenosine-5',5'',5'''-tris(phosphate) as a branch linkage.

Proceedings of the National Academy of Sciences of the United States of America, 1979
Masanao Miwa, Z Yamaizumi, Yamaizumi Z   +2 more
exaly   +2 more sources

Well-Defined Adenosine Diphosphate Ribose Oligomers

Synfacts, 2015
Y. Uozumi, Yoichi M. A. Yamada, Takuma Sato   +2 more
openaire   +2 more sources

Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure

Journal of the American College of Cardiology, 2002
ObjectivesWe investigated the effects of a novel ultrapotent poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitor, PJ34, on cardiac and endothelial dysfunction in a rat model of chronic heart failure (CHF).BackgroundOveractivation of the ...
Pal Pacher, Lucas Liaudet, Katalin Komjati   +2 more
exaly   +2 more sources

Hypoxic pulmonary vasoconstriction: cyclic adenosine diphosphate-ribose, smooth muscle Ca2+ stores and the endothelium

Respiratory Physiology and Neurobiology, 2002
Hypoxic pulmonary vasoconstriction (HPV) is unique to pulmonary arteries, and supports ventilation/perfusion matching. However, in diseases such as emphysema, HPV can promote hypoxic pulmonary hypertension (HPH), which ultimately leads to right heart ...
A Mark Evans, Michelle Dipp
exaly   +2 more sources

Poly(adenosine diphosphate ribose)

1973
Publisher Summary This chapter discusses that incorporation of radioactivity of (adenine- 14 C) ATP into the acid insoluble material in a nuclear preparation from hen liver is enhanced at least 1000-fold by the presence of NMN. It is confirmed that this stimulation: using a nuclear preparation from rat liver.
openaire   +2 more sources

Studies on anti-poly(adenosine diphosphate ribose) antibody

Biochemical and Biophysical Research Communications, 1974
Summary Specific antibody against poly(ADP-Rib) was produced in a rabbit by injecting poly(ADP-Rib) mixed with methylated bovine serum albumin. Under standardized conditions, 1 mg of purified anti-poly(ADP-Rib) antibody combined with 400 pmoles (4 μg) of poly(ADP-Rib) and was retained on a millipore filter.
Y, Kanai, M, Miwa, T, Matsushima, T, Sugimura   +3 more
openaire   +2 more sources

Poly(adenosine diphosphate ribose) glycohydrolase in Physarum polycephalum

Archives of Biochemistry and Biophysics, 1976
Abstract Poly(adenosine diphosphate ribose) glycohydrolase, which has thus far only been found in mammalian tissues, was found for the first time in the primitive eukaryotic slime mold Physarum polycephalum. The hydrolytic product of poly(adenosine diphosphate ribose) with this enzyme was identified as adenosine diphosphate ribose by paper and thin ...
M, Tanaka, M, Miwa, T, Matsushima, T, Sugimura, S, Shall   +4 more
openaire   +2 more sources