Results 191 to 200 of about 34,973 (226)

Noncovalent interactions of poly(adenosine diphosphate ribose) with histones

Biochemistry, 1992
Covalent linkage of ADP-ribose polymers to proteins is generally considered essential for the posttranslational modification of protein function by poly(ADP-ribosyl)ation. Here we demonstrate an alternative way by which ADP-ribose polymers may modify protein function.
Panzeter PL, Realini CA, Althaus FR
openaire   +3 more sources

Nonenzymic adenosine 5'-diphosphate ribosylation of poly(adenosine diphosphate ribose).

Biochemistry, 1986
Poly(adenosine 5'-diphosphate ribose) [poly(ADP-ribose]) is spontaneously ADP-ribosylated when it is incubated with nicotinamide adenine dinucleotide, especially in 0.5 M NaCl and at an alkaline pH. The ADP-ribose residues are monomeric and are attached to the middle of polymer chains.
M, Ikejima, D M, Gill
openaire   +1 more source

Characterization of polymers of adenosine diphosphate ribose generated in vitro and in vivo

Biochemistry, 1987
Methods have been developed and applied to determine the size and branching frequency of polymers of ADP-ribose synthesized in nucleotide-permeable cultured mouse cells and in intact cultured cells. Polymers were purified by affinity chromatography with a boronate resin and were fractionated according to size molecular sieve high-performance liquid ...
R, Alvarez-Gonzalez, M K, Jacobson
openaire   +2 more sources

The Involvement of Poly(Adenosine Diphosphate-Ribose) in Deoxyribonucleic Acid Repair

Biochemical Society Transactions, 1978
Poly(ADP-ribose) is a nuclear protein modification whose synthesis from NAD is catalysed by the chromatin-bound DNA-dependent enzyme poly(ADP-ri bose) polymerase (Hilz S Hayaishi & Ueda, 1977). The majority of the extensive NAD turnover that takes place in mammalian cells is localized in the nucleus and is thought to involve this enzyme (Rechsteiner et
M I, Davies, H, Halldorsson, N, Nduka, S, Shall, C J, Skidmore   +4 more
openaire   +2 more sources

Properties of Poly(Adenosine Diphosphate Ribose) Polymerase, Poly(Adenosine Diphosphate Ribose) Glycohydrolase and Poly(Adenosine Diphosphate Ribose)

Biochemical Society Transactions, 1973
TAKASHI SUGIMURA, MICHIYUKI YAMADA, MASANAO MIWA, TAIJIRO MATSUSHIMA, TAKAYOSHI HIDAKA, MINAKO NAGAO, NAOMICHI INUI, SHOZO TAKAYAMA   +7 more
openaire   +1 more source

An update on current and emerging therapies for epithelial ovarian cancer: Focus on poly(adenosine diphosphate-ribose) polymerase inhibition and antiangiogenesis

Journal of Oncology Pharmacy Practice, 2017
C. Chung, Rosetta Lee
semanticscholar   +1 more source

Inhibition of poly(adenosine diphosphate-ribose) polymerase using quinazolinone nucleus

Applied Microbiology and Biotechnology, 2016
K. Hemalatha, G. Madhumitha
semanticscholar   +1 more source

The crystal structure of type III effector protein XopQ from Xanthomonas oryzae complexed with adenosine diphosphate ribose

Proteins: Structure, Function, and Bioinformatics, 2014
Sangheon Yu, I. Hwang, S. Rhee
semanticscholar   +1 more source

Co-targeting deoxyribonucleic acid-dependent protein kinase and poly(adenosine diphosphate-ribose) polymerase-1 promotes accelerated senescence of irradiated cancer cells.

International Journal of Radiation Oncology, Biology, Physics, 2014
A. Azad, P. Bukczynska, Susan Jackson, Y. Haupt, C. Cullinane, G. McArthur, B. Solomon   +6 more
semanticscholar   +1 more source

Adenosine diphosphate ribosylation of histone H1 by purified calf thymus polyadenosine diphosphate ribose polymerase.

Biochimie, 1980
H. Okazaki, C. Niedergang, Paul Mandel
semanticscholar   +1 more source