Adenosine-Metabolizing Enzymes, Adenosine Kinase and Adenosine Deaminase, in Cancer [PDF]
Biomolecules, 2022 The immunosuppressive effect of adenosine in the microenvironment of a tumor is well established. Presently, researchers are developing approaches in immune therapy that target inhibition of adenosine or its signaling such as CD39 or CD73 inhibiting ...
Galina Zhulai +3 more
doaj +4 more sources
Adenosine kinase deficiency presenting with tortuous cervical arteries: A risk factor for recurrent stroke [PDF]
JIMD Reports, 2021 Adenosine kinase (ADK) deficiency is a very rare inborn error of methionine and adenosine metabolism. It is characterized by developmental delay, hypotonia, epilepsy, facial dysmorphism, failure to thrive, transient liver dysfunction with cholestasis ...
José A. Paz +9 more
doaj +4 more sources
Adenosine Kinase on Deoxyribonucleic Acid Methylation: Adenosine Receptor-Independent Pathway in Cancer Therapy [PDF]
Frontiers in Pharmacology, 2022 Methylation is an important mechanism contributing to cancer pathology. Methylation of tumor suppressor genes and oncogenes has been closely associated with tumor occurrence and development.
Hao-Yun Luo +5 more
doaj +2 more sources
Case Report: Adenosine kinase deficiency diagnosed 10 years after liver transplantation: Novel phenotypic insights [PDF]
Frontiers in Pediatrics, 2022 Adenosine kinase (ADK) deficiency is a rare inborn error of methionine and adenosine metabolism. So far, a total of 27 patients with ADK deficiency have been reported.
Patryk Lipiński +7 more
doaj +2 more sources
Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis [PDF]
Frontiers in Cell and Developmental Biology, 2022 Background: Inflammatory disorder and acinar cell death contribute to the initiation and progression of severe acute pancreatitis (SAP). Adenosine kinase (ADK) has potential effects on both inflammation and cell death.
Shukun Sun +32 more
doaj +2 more sources
Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase. [PDF]
PLoS ONE, 2019 Cordycepin is an efficient component of Cordyceps spp, a traditional Chinese medicine widely used for healthcare in China, and has been recently acted as a strong anticancer agent for clinic.
Feng Huang +4 more
doaj +2 more sources
Corrigendum: Adenosine kinase on deoxyribonucleic acid methylation: Adenosine receptor-independent pathway in cancer therapy [PDF]
Frontiers in Pharmacology, 2023 Hao-Yun Luo +5 more
doaj +2 more sources
Deep brain stimulation of the anterior thalamus attenuates PTZ kindling with concomitant reduction of adenosine kinase expression in rats. [PDF]
Brain Stimul, 2022 Gimenes C +5 more
europepmc +2 more sources
Adenosine Kinase Expression Determines DNA Methylation in Cancer Cell Lines. [PDF]
ACS Pharmacol Transl Sci, 2021 Wahba AE +6 more
europepmc +3 more sources
Dysregulation of adenosine kinase isoforms in breast cancer. [PDF]
Oncotarget, 2019 Shamloo B +6 more
europepmc +3 more sources