Results 1 to 10 of about 293,395 (315)
Structure of Klebsiella pneumoniae adenosine monophosphate nucleosidase. [PDF]
PLoS One, 2022 Klebsiella pneumoniae is a bacterial pathogen that is increasingly responsible for hospital-acquired pneumonia and sepsis. Progressive development of antibiotic resistance has led to higher mortality rates and creates a need for novel treatments. Because of the essential role that nucleotides play in many bacterial processes, enzymes involved in purine
Richardson BC +3 more
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Cyclic Adenosine Monophosphate and Cardiac Contractility [PDF]
Circulation Research, 1973 Burton E. Sobel, Steven E. Mayer
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Adenosine monophosphate deaminase deficiency
Definitions, 2020 Adenosine monophosphate (AMP) deaminase deficiency is a condition that can affect the muscles used for movement (skeletal muscles). In many affected individuals, AMP deaminase deficiency does not cause any symptoms.
G. Berghe
semanticscholar +1 more source
Adenosine-Metabolizing Enzymes, Adenosine Kinase and Adenosine Deaminase, in Cancer
Biomolecules, 2022 The immunosuppressive effect of adenosine in the microenvironment of a tumor is well established. Presently, researchers are developing approaches in immune therapy that target inhibition of adenosine or its signaling such as CD39 or CD73 inhibiting ...
G. Zhulai +3 more
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Hepatology, 2018 Chronic hepatitis B virus (HBV) infection is a major cause of chronic liver disease and cancer worldwide. The mechanisms of viral genome sensing and the evasion of innate immune responses by HBV infection are still poorly understood. Recently, the cyclic
Eloi R. Verrier +16 more
semanticscholar +1 more source
Phosphorylation of adenosine monophosphate in the mitochondrial matrix [PDF]
Biochemical Journal, 1978 The origin of the GTP needed for th phosphorylation of AMP in the mitochondrial matrix was investigated. When short-chain fatty acids are metabolized by hepatocytes, AMP is readily formed within the matrix by the butyryl-CoA ligase (AMP-forming) reaction (EC 6.2.1.2).
D Wiggins, H A Krebs
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Adenosine Monophosphate (AMP)-Activated Protein Kinase: A New Target for Nutraceutical Compounds
International Journal of Molecular Sciences, 2017 Adenosine monophosphate-activated protein kinase (AMPK) is an important energy sensor which is activated by increases in adenosine monophosphate (AMP)/adenosine triphosphate (ATP) ratio and/or adenosine diphosphate (ADP)/ATP ratio, and increases ...
F. Marín-Aguilar +4 more
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Neutral ditopic receptors for adenosine monophosphate [PDF]
Tetrahedron Letters, 1994 Novel neutral ditopic receptors for AMP2- consisting of an immobilised Lewis acidic uranyl centre covalently coupled to thymine are described.
David N. Reinhoudt +3 more
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Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017 Since the incidence of breast cancer increases dramatically all over the world, the search for effective treatment is an urgent need. Metformin has demonstrated anti-tumorigenic effect both in vivo and in vitro in different cancer types.
N. El-Ashmawy +3 more
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Cyclic adenosine monophosphate, CA++, and membranes. [PDF]
Proceedings of the National Academy of Sciences, 1968 Since the initial discovery of cyclic 3',5'-adenosine monophosphate (3',5'AMP) by Rall, Sutherland, and Berthet' and its role in glycogenolysis in the liver,2 evidence has accumulated indicating that this nucleotide is an intermediate in the action of many peptide hormones.3-9 More recently it has also been implicated in the release of insulin from the
Howard Rasmussen, Alan Tenenhouse
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