Results 191 to 200 of about 2,712,589 (407)

Impaired Inhibitory Function of Presynaptic A1-Adenosine Receptors in SHR Mesenteric Arteries

Journal of Pharmacological Sciences, 2013
In hypertension, vascular reactivity alterations have been attributed to numerous factors, including higher sympathetic innervation/adenosine. This study examined the modulation of adenosine receptors on vascular sympathetic nerves and their putative ...
Carolina Rocha-Pereira, Silvia Magdalena Arribas, Paula Fresco, Maria Carmen González, Jorge Gonçalves, Carmen Diniz   +5 more
doaj  

In Vitro Transcription of the Gal Operon Requires Cyclic Adenosine Monophosphate and Cyclic Adenosine Monophosphate Receptor Protein

, 1971
S. Peter Nissley, Wayne B. Anderson, Max E. Gottesman, Robert L. Perlman, Ira Pastan   +4 more
openalex   +1 more source

Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury

Advanced Science, EarlyView.
Dipyridamole acts as a clinically used compound to suppress ferroptosis. Dipyridamole down‐regulates the expression of RNF126, which is an E3 ligase to ubiquitinate SLC7A11 for proteasome degradation. The deficiency of SLC7A11 largely abolishes the protective role of dipyridamole both in vitro and in vivo.
Xiao Zhuang, Shuang Shi, Shuo Liu, Yaqiong Jiao, Bin Huang, Yinghong Yang, Li Yang, Xinquan Yang, Hui Wang, Chunhui Liang, Dandan Song, Huaxiang Yu, Dan Zou, Qi Sun, Shu Yang, Chengqian Yin, Jian Li, Yiming Liu, Junxia Min, Fudi Wang, Yong Nian, Lutao Du, Bo Chu   +22 more
wiley   +1 more source

Binding of 125I-labeled glucagon and glucagon-stimulated accumulation of adenosine 3‘:5‘-monophosphate in isolated intact rat hepatocytes. Evidence for receptor heterogeneity.

, 1978
O. Sonne, Trond Berg, Thoralf Christoffersen   +2 more
openalex   +1 more source

EVIDENCE FOR SPECIFIC ADENOSINE RECEPTORS AT CHOLINERGIC NERVE ENDINGS [PDF]

, 1980
Eugene M. Silinsky
openalex   +1 more source

High‐Efficiency Carriers’ Separation Strategy Based Ultrasmall‐Bandgap CuWO4 Sono‐Enhances GSH Antagonism for Cuproptosis Cascade Immunotherapy

Advanced Science, EarlyView.
This study prepares copper tungstate (CuWO4, CWO) nanoparticles for synergistic sono‐enhanced cuproptosis‐based cancer therapy. With an ultrasmall bandgap (1.71 eV), CWO facilitates efficient charge carrier separation under ultrasound, enhancing the generation of reactive oxygen species and the controlled release of Cu2+ ions cascade amplify oxidative ...
Lichao Zhu, Zhisheng Guo, Yu Luo, Haiyan Huang, Kexin Zhang, Bingbing Duan, Renmiao Peng, Haochen Yao, Chao Liang, Kaiyang Wang   +9 more
wiley   +1 more source

A_2A adenosine receptor-driven cAMP signaling in olfactory bulb astrocytes is unaffected in experimental autoimmune encephalomyelitis. [PDF]

Front Immunol, 2023
Wendlandt M, Kürten AJ, Beiersdorfer A, Schubert C, Samad-Yazdtchi K, Sauer J, Pinto MC, Schulz K, Friese MA, Gee CE, Hirnet D, Lohr C.   +11 more
europepmc   +1 more source

A1 and A2 adenosine receptors in rabbit cortical collecting tubule cells. Modulation of hormone-stimulated cAMP. [PDF]

, 1987
Lois J. Arend, W. K. Sonnenburg, William L. Smith, W. S. Spielman   +3 more
openalex   +1 more source

Wogonin Attenuates Atherosclerosis via KLF11‐Mediated Suppression of PPARα‐YAP1‐Driven Glycolysis and Enhancement of ABCA1/G1‐Mediated Cholesterol Efflux

Advanced Science, EarlyView.
PPARα promotes KLF11 expression and recruits KLF11 and YAP1 to form a transcription complex, where KLF11 acts as a brake in PPARα‐YAP1‐mediated glycolysis. Wogonin reshapes the metabolism of macrophages from glycolysis to fatty acid oxidation via activation of the PPARα‐KLF11‐YAP1 pathway, by which wogonin reduces inflammation and foam cell formation ...
Chuanrui Ma, Yunqing Hua, Shu Yang, Yun Zhao, Wei Zhang, Yaodong Miao, Jing Zhang, Boxuan Feng, Guobin Zheng, Lan Li, Zhihao Liu, Han Zhang, Mingjun Zhu, Xiumei Gao, Guanwei Fan   +14 more
wiley   +1 more source

Improving combination therapies: targeting A2B-adenosine receptor to modulate metabolic tumor microenvironment and immunosuppression. [PDF]

J Natl Cancer Inst, 2023
Evans JV, Suman S, Goruganthu MUL, Tchekneva EE, Guan S, Arasada RR, Antonucci A, Piao L, Ilgisonis I, Bobko AA, Driesschaert B, Uzhachenko RV, Hoyd R, Samouilov A, Amann J, Wu R, Wei L, Pallerla A, Ryzhov SV, Feoktistov I, Park KP, Kikuchi T, Castro J, Ivanova AV, Kanagasabai T, Owen DH, Spakowicz DJ, Zweier JL, Carbone DP, Novitskiy SV, Khramtsov VV, Shanker A, Dikov MM.   +32 more
europepmc   +1 more source