Results 201 to 210 of about 2,608,509 (268)

Immunometabolic Rewiring of Dendritic Cells to Overcome Glutamine‐Driven Immune Suppression in Colorectal Cancer

Advanced Science, EarlyView.
T26 is an immunometabolic prodrug that modulates colorectal cancer cells. It blocks glutamine metabolism and enhances STING signaling, which promotes the release of reprogrammed extracellular vesicles. These vesicles drive dendritic cell maturation and CD8⁺ T cell activation, thereby strengthening antitumor immunity and improving the effectiveness of ...
Bingjie Zhang, Renming Fan, Yongrui Hai, Ye Chen, Xintong Lu, Wenhui Wang, Jiarui Dou, Jiaxin Yan, Chang Su, Yue Chen, Le Yang, Minggao Zhao, Lei Liang, Gaofei Wei   +13 more
wiley   +1 more source

Mesoionic xanthine analogs: antagonists of adenosine receptors

, 1984
Richard A. Glennon, Shanaz M. Tejani‐Butt, William L. Padgett, John W. Daly   +3 more
openalex   +1 more source

The Adenosine-Dependent Angiogenic Switch of Macrophages to an M2-Like Phenotype is Independent of Interleukin-4 Receptor Alpha (IL-4Rα) Signaling

Inflammation, 2013
C. Ferrante, Grace Pinhal‐Enfield, G. Elson, B. Cronstein, G. Haskó, S. Outram, S. Leibovich   +6 more
semanticscholar   +1 more source

Emerging Nanozyme Strategies for Precision Breast Cancer Treatment

Advanced Science, EarlyView.
Different types of nanozymes‐mediated chemotherapy, photothermal therapy, immunotherapy, and multiple combined therapies for the effective treatment of breast cancer. Abstract Breast cancer, the most common malignant tumor among women worldwide, poses a significant challenge to public health due to its high incidence and mortality rates.
Jian Zang, Zhaozhou Ren, Haibo Wang, Xing Yang, Yang Song, Jun Liao, Xiaoying Li   +6 more
wiley   +1 more source

Correction: A2B Adenosine Receptor Expression by Myeloid Cells is Proinflammatory in Murine Allergic-Airway Inflammation. [PDF]

J Immunol
Belikoff BG, Vaickus LJ, Sitkovsky M, Remick DG.   +3 more
europepmc   +1 more source

Pharmacological and therapeutic effects of A3 adenosine receptor agonists.

Drug Discovery Today, 2012
P. Fishman, S. Bar‐Yehuda, B. Liang, K. Jacobson   +3 more
semanticscholar   +1 more source

Photo‐Empowered Macrophage‐Based Drug Delivery System Overcomes Motility Suppression and Significantly Enhances Deep Tumor Drug Delivery

Advanced Science, EarlyView.
This study develops a photo‐empowered macrophage‐based (PEM) drug delivery system that provides a novel and effective solution for restoring cellular motility to enhance drug delivery and overcome hypoxia‐induced multidrug resistance. The construction of the PEM system fully exploits the unique biological properties of macrophages and the energy ...
Zhaoming Fu, Xin Cui, Shanshan Liu, Lu Gao, Yingang Sun, Yujun Chen, Mianlong Li, Yuxin Fan, Jing Kuang, Wen Song, Feifan Zhou   +10 more
wiley   +1 more source

Adenosine Augments IL-10 Production by Microglial Cells through an A2B Adenosine Receptor-Mediated Process

Journal of Immunology, 2012
Balázs Koscsó, B. Csóka, Z. Selmeczy, Leonóra Himer, P. Pacher, L. Virág, G. Haskó   +6 more
semanticscholar   +1 more source

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source