Results 31 to 40 of about 17,597 (256)

ADENOSINE TRIPHOSPHATASE LOCALIZATION IN AMPHIBIAN EPIDERMIS [PDF]

The Journal of Cell Biology, 1966
The localization of ATPase1 activity has been studied by light and electron microscopy in the epidermis of Rana pipiens, Rana catesbiana, and Bufo marinus. The reaction was carried out on skin (glutaraldehyde-fixed or fresh) sectioned with or without freezing. Best results were obtained with nonfrozen sections of fixed tissue.
M G, Farquhar, G E, Palade
openaire   +2 more sources

Sestrin2 is a leucine sensor for the mTORC1 pathway [PDF]

, 2016
Leucine is a proteogenic amino acid that also regulates many aspects of mammalian physiology, in large part by activating the mTOR complex 1 (mTORC1) protein kinase, a master growth controller.
Cantor, J. R., Chantranupong, Lynne, Sabatini, David, Saxton, Robert Andrew, Scaria, Sonia M., Shen, K., Wolfson, Rachel Laura   +6 more
core   +1 more source

ADENOSINE TRIPHOSPHATASE IN THE MITOTIC APPARATUS [PDF]

Proceedings of the National Academy of Sciences, 1961
Methods.-Isolation of the mitotic apparatus: The principle of the new method has been described in several publications, and a detailed account of the procedure will appear shortly.5 Sea urchin eggs (Stronglycentrotus purpuratus) are the source of material, providing large quantities of cells in synchronous division.
D, MAZIA, R R, CHAFFEE, R M, IVERSON
openaire   +2 more sources

Dissolved Organic Phosphorus Utilization by Phytoplankton Reveals Preferential Degradation of Polyphosphates Over Phosphomonoesters

Frontiers in Marine Science, 2018
The nutritionally available pool of dissolved organic phosphorus (DOP) supports marine primary productivity in a range of ocean ecosystems but remains poorly resolved. Here, the relative lability of model phosphorus (P) compounds representing the major P(
Julia M. Diaz, Alisia Holland, James G. Sanders, Karrie Bulski, Douglas Mollett, Douglas Mollett, Chau-Wen Chou, Dennis Phillips, Yuanzhi Tang, Solange Duhamel   +9 more
doaj   +1 more source

LEAD-ADENOSINE TRIPHOSPHATE COMPLEXES IN ADENOSINE TRIPHOSPHATASE HISTOCHEMISTRY [PDF]

Journal of Histochemistry & Cytochemistry, 1969
Chelation of lead by adenosine triphosphate (ATP) and its consequences for adenosine triphosphatase histochemistry were examined. The formation constant of lead-ATP chelates was found by two methods to be 4.6-4.7 x 104. The characteristics of enzyme inhibition by lead were consistent with the predicted effects of lead-ATP chelation.
openaire   +2 more sources

Estimating the Rotation Rate in the Vacuolar Proton-ATPase in Native Yeast Vacuolar Membranes [PDF]

, 2012
The rate of rotation of the rotor of the yeast vacuolar proton-ATPase (V-ATPase), relative to the stator or the steady parts of enzyme, is estimated in native vacuolar membrane vesicles of Saccharomyces cerevisiae under standardised conditions.
Bóta, A., Dér, A., Ferencz, C., Fodor-Ayaydin, E., Haracska, L., Kóta, Z., Marsh, D., Petrovszki, P., Páli, T., Varga, Z.   +9 more
core   +1 more source

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase [PDF]

, 2011
The mTOR complex 1 (mTORC1) protein kinase is a master growth regulator that is stimulated by amino acids. Amino acids activate the Rag guanosine triphosphatases (GTPases), which promote the translocation of mTORC1 to the lysosomal surface, the site of ...
Bar-Peled, Liron, Efeyan, Alejo, Sabatini, David M., Sancak, Yasemin, Wang, Shuyu, Ph. D. Massachusetts Institute of Technology, Zoncu, Roberto   +5 more
core   +1 more source

ATP6V1A deletion leads to impaired clearance of septic cardiac resident macrophages

陆军军医大学学报
Objective To investigate the clearance capacity of cardiac resident macrophages in post-sepsis and its underlying mechanism. Methods A mouse model of sepsis was established using cecum perforation ligation. Thirty male C57BL/6 mice (8 weeks old, weighing
YANG Shunxin, ZHOU Yuanqun, XIANG Xinming   +2 more
doaj   +1 more source

Production of a new Plant-Based Milk from Adenanthera pavonina seed and evaluation of its nutritional and health Benefits [PDF]

, 2018
A new plant milk was discovered from the seed of Adenanthera pavonina. The physicochemical and nutritional properties of the new pro-milk extract were assessed, and their biochemical effects were compared with those of soy bean extracts.
Adegbite, Olawunmi Adebisi, Afolabi , Israel Sunmola, Ezeoke, Chinemelum Sandra, Martins, Olubukola C., Nwachukwu, C., Olawole, Tolulope Dorcas, Woke, Ruth Chineme   +6 more
core   +2 more sources

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source