Results 41 to 50 of about 17,343 (255)
Ultraslow water-mediated transmembrane interactions regulate the activation of A$_{\text{2A}}$ adenosine receptor [PDF]
Biophys. J. (2016) vol. 111, 1180-1191, 2016 Water molecules inside G-protein coupled receptor have recently been spotlighted in a series of crystal structures. To decipher the dynamics and functional roles of internal waters in GPCR activity, we studied A$_{\text{2A}}$ adenosine receptor using $\mu$sec-molecular dynamics simulations.
arxiv +1 more source
Sestrin2 is a leucine sensor for the mTORC1 pathway [PDF]
, 2016 Leucine is a proteogenic amino acid that also regulates many aspects of mammalian physiology, in large part by activating the mTOR complex 1 (mTORC1) protein kinase, a master growth controller.
Cantor, J. R. +6 more
core +1 more source
The enzyme activity dynamic relationship with the content of structural polypeptides of enterocyte membranes in cattle fetal [PDF]
, 2021 The article performs new data on the relationship between the hydrolytic and transport enzyme activity at different poles of the enterocytes plasmolemma of cow's fetal large intestine with the content of individual fractions of polypeptides.
Masiuk, D. M.
core +2 more sources
Mitochondrial dynamics in autoimmune diseases
Rheumatology &Autoimmunity, EarlyView.Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma +5 more
wiley +1 more source
Mechanisms of Degranulation in Neutrophils [PDF]
, 2006 Neutrophils are critical inflammatory cells that cause tissue damage in a range of diseases and disorders. Being bone marrow-derived white blood cells, they migrate from the bloodstream to sites of tissue inflammation in response to chemotactic signals ...
Lacy, Paige
core +3 more sources
An exceptional case of peritoneal cystic echinococcosis in a domestic cat in Australia
Australian Veterinary Journal, Volume 103, Issue 5, Page 254-260, May 2025.A case of peritoneal cystic echinococcosis (CE) in a domestic cat was reported from Queensland, Australia. Physical examination of the cat indicated a large, distended abdomen, which when palpated appeared to be fluid‐filled. Ultrasonography showed numerous cysts with hyperechoic walls and anechoic contents within the cat's abdominal cavity.
S Abdullah +6 more
wiley +1 more source
Broadband terahertz time-domain spectroscopy and fast FMCW imaging: principle and applications [PDF]
, 2020 We report a broadband terahertz time-domain spectroscopy (THz-TDS) which enables twenty vibrational modes of adenosine nucleoside to be resolved in a wide frequency range of 1-20 THz. The observed spectroscopic features of adenosine are in good agreement with the published spectra obtained using Fourier Transform Infrared Spectroscopy (FTIR) and Raman ...
arxiv +1 more source
Ultrastructural localization of adenosine triphosphatase activity in lymphocytes activated in vitro by phytohaemagglutinin [PDF]
, 1982 The ultrastructural localization of Ca 2+, Mg2+ -activated ATPase was studied in phytohaemagglutinin activated lymphocytes and in normal unstimulated lymphocytes. Cells, fixed in paraformaldehyde-glutaraldehyde, were incubated in a medium containing 3 mM
Cuschieri, Alfred +2 more
core
Toward molecular phenotyping of temporal lobe epilepsy by spatial omics
Epilepsia, EarlyView.Abstract Objective In temporal lobe epilepsy (TLE), detection of the epileptogenic zone predicts a good surgical outcome. When submitted to 18F‐fluorodeoxyglucose positron emission tomography (PET), some patients display lateralized, focal hypometabolism in the temporal lobe (PET+), whereas others appear normometabolic (PET−).
Isabeau Vermeulen +33 more
wiley +1 more source
UV resistance of nucleosides -- an experimental approach [PDF]
, 2020 The emergence of life on Earth is a highly discussed but still unsolved question. Current research underlines the importance of environments within close proximity to the Earth's surface as they can solve long-standing problems such as polymerization of nucleotides and phosphorylation of nucleosides.
arxiv +1 more source