Lysosomal redistribution occurs via extracellular vesicles in multi‐stem cell aggregates and controls iron homeostasis for safeguarding cell aggregation. These cell aggregate‐released extracellular vesicles (CA‐EVs) rescue lysosomal impairments and exert anti‐ferroptosis effects in recipient irradiated endothelial cells.
Yuan‐Yuan Li+20 more
wiley +1 more source
Ultrastructural localization of adenosine triphosphatase activity in lymphocytes activated in vitro by phytohaemagglutinin [PDF]
The ultrastructural localization of Ca 2+, Mg2+ -activated ATPase was studied in phytohaemagglutinin activated lymphocytes and in normal unstimulated lymphocytes. Cells, fixed in paraformaldehyde-glutaraldehyde, were incubated in a medium containing 3 mM
Cuschieri, Alfred+2 more
core
Exploring Immediate Photon Effects From 635 nm Light on Mitochondrial Bioenergetics
The investigation of in vitro impacts of 635 nm laser irradiation in mitochondrial bioenergetics demonstrated that red light induces transient and localized effects, highlighting the complexities of cellular and mitochondrial photostimulation mechanisms. ABSTRACT Visible light primarily targets mitochondria at the cellular level, but photon interaction
Natasha F. Mezzacappo+6 more
wiley +1 more source
Mitochondrial dynamics in autoimmune diseases
Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma+5 more
wiley +1 more source
Analysis of the Movement of Chlamydomonas Flagella: The Function of the Radial-spoke System Is Revealed by Comparison of Wild-type and Mutant Flagella [PDF]
The mutation uni-1 gives rise to uniflagellate Chlamydomonas cells which rotate around a fixed point in the microscope field, so that the flagellar bending pattern can be photographed easily .
Brokaw, C. J., Huang, B., Luck, D. J. L
core
Plasma membrane Ca2+-ATPases can shape the pattern of Ca2+ transients induced by store-operated Ca2+ entry [PDF]
Calcium (Ca2+) is a critical cofactor and signaling mediator in cells, and the concentration of cytosolic Ca2+ is regulated by multiple proteins, including the plasma membrane Ca2+-ATPases (adenosine triphosphatases) (PMCAs), which use ATP to transport ...
Bajzer, Ž.+5 more
core +1 more source
Adenosine Triphosphatase Activity of the Vascular System.
SummaryThe AT Pase activity of the vascular system of the dog has been studied, lit has been shown that the enzyme content of -the different arteries enjoys wide variation. The venous system does not contain the enzyme. ATPase activity of the aorta of the rat was not influenced by age or captivity.
Carr Cj+2 more
openaire +3 more sources
Epigenetic control of cell identities from epiblast to gastrulation
In this review, we present and contextualize current knowledge about the roles of epigenetic modifiers during the development of mouse epiblast to gastrulation stage. The epigenetic regulation of enhancer and promoter elements by DNA methylation, histone modifications, and chromatin accessibility in concert with lineage‐specific transcription factors ...
Katrin M. Schüle, Simone Probst
wiley +1 more source
Omics approaches to identify potential biomarkers of inflammatory diseases in the focal adhesion complex [PDF]
Inflammatory diseases such as inflammatory bowel disease require recurrent invasive tests, including blood tests, radiology and endoscopic evaluation for diagnosis, assessment of disease activity and to determine optimal therapeutic strategies. ‘Bedside’
Ab Mutalib+81 more
core +2 more sources
Abstract figure legend AC: adenylyl cyclase, APT: adenosine triphosphate, AMP: adenosine monophosphate, cAMP: cyclic adenosine monophosphate, PDE: phosphodiesterase, PKA: protein kinase A, PPT: protein phosphatase, P: phosphorylation, RyR: ryanodine receptor, SERCA: sarcoplasmic/endoplasmic reticulum Ca2+‐adenosine triphosphatase, SR: sarcoplasmic ...
Moritz Linder+4 more
wiley +1 more source