Results 61 to 70 of about 17,484 (250)

Large-Scale Discovery of ERK2 Substrates Identifies ERK-Mediated Transcriptional Regulation by ETV3 [PDF]

, 2011
The mitogen-activated protein kinase (MAPK) extracellular signal–regulated kinase 2 (ERK2) is ubiquitously expressed in mammalian tissues and is involved in a wide range of biological processes.
Carlson, Scott M., Chouinard, Candace R., Fraenkel, Ernest, Labadorf, Adam, Lam, Carol J., Schmelzle, Katrin, White, Forest M.   +6 more
core   +1 more source

Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation [PDF]

, 2004
The capacitation of mammalian spermatozoa involves the activation of a cAMP-mediated signal transduction pathway that drives tyrosine phosphorylation via mechanisms that are unique to this cell type.
Aitken, R. John, Baker, Mark A., Ecroyd, Heath William, Hetherington, Louise, Roman, Shaun D.   +4 more
core   +2 more sources

Identifying putative calcification and decalcification genes in the geniculate coralline alga, Calliarthron tuberculosum

Journal of Phycology, EarlyView.
Abstract Coralline algae form highly calcified thalli, creating key substrate that promotes biodiversity in nearshore marine environments. Although calcification and decalcification are critical for coralline growth and ecological function, their underlying mechanisms are not fully understood.
Emmaeve Jourdain, Patrick T. Martone
wiley   +1 more source

Mechanisms of phenolic biosynthesis induced by ultrasound stress in fresh-cut red cabbages based on energy metabolism analysis

Food Physics
In our previous studies, ultrasonic washing was proven to induce phenolic biosynthesis in fresh-cut red cabbages; however, the related regulatory mechanisms remain unclear.
Ningning Ouyang, Chen Hong, Lina Guo, Xinyan Zhang, Wenjuan Qu, Haile Ma   +5 more
doaj   +1 more source

Omics approaches to identify potential biomarkers of inflammatory diseases in the focal adhesion complex [PDF]

, 2017
Inflammatory diseases such as inflammatory bowel disease require recurrent invasive tests, including blood tests, radiology and endoscopic evaluation for diagnosis, assessment of disease activity and to determine optimal therapeutic strategies. ‘Bedside’
Ab Mutalib, Abshire, Alanko, Alastair Watson, Ambros, Bader, Barnett, Beausejour, Berger, Bouchard, Brandse, Cai, Case, Chan, Chapman, Chen, Chen, Choudhary, Chung, Dennis, Dixit, Eitel, Fuste, Geiger, Goicoechea, Goldmann, Guo, He, He, Holle, Iioka, Jahed, Johanne Brooks, Johnson, Kanehisa, Kato, Khan, Klimova, Leavitt, MacGillivray, Marquez, Maruoka, May, Mikeska, Nakano, Nakashima, Nowarski, Omran, Pardi, Perlis, Peterson, Plenge, Plevy, Ritchie, Rukmangadachar, Salim, Schiffhauer, Shi, Shibanuma, Shuto, Spalinger, Szasz, Tachibana, Tamas Korcsmaros, Thinwa, Trevino, Villani, von Mering, Wang, Wang, Weaver, Xin, Xu, Yang, You, Yu, Zaidel-Bar, Zhang, Zhang, Zhao, Zheng, Zheng   +81 more
core   +2 more sources

Sympathetic stimulation can compensate for hypocalcaemia‐induced bradycardia in human and rabbit sinoatrial node cells

The Journal of Physiology, EarlyView.
Abstract figure legend AC: adenylyl cyclase, APT: adenosine triphosphate, AMP: adenosine monophosphate, cAMP: cyclic adenosine monophosphate, PDE: phosphodiesterase, PKA: protein kinase A, PPT: protein phosphatase, P: phosphorylation, RyR: ryanodine receptor, SERCA: sarcoplasmic/endoplasmic reticulum Ca2+‐adenosine triphosphatase, SR: sarcoplasmic ...
Moritz Linder, Tomas Stary, Gergő Bitay, Norbert Nagy, Axel Loewe   +4 more
wiley   +1 more source

Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM [PDF]

, 2019
The human R2TP complex (RUVBL1-RUVBL2-RPAP3-PIH1D1) is an HSP90 co-chaperone required for the maturation of several essential multiprotein complexes, including RNA polymerase II, small nucleolar ribonucleoproteins, and PIKK complexes such as mTORC1 and ...
Fernandez-Leiro, Rafael, Llorca, Oscar, Muñoz-Hernández, Hugo, Pal, Mohinder, Pearl, Laurence H, Prodromou, Chrisostomos, Rodríguez, Carlos F   +6 more
core   +3 more sources

Genome‐wide association study of seed mineral nutrients in peas (Pisum sativum L.)

The Plant Genome, Volume 18, Issue 4, December 2025.
Abstract Pea (Pisum sativum L.) is an important crop with high nutritional value and agricultural benefits. This study aimed to identify genetic factors that influence the levels of mineral elements (B, Ca, Cu, Fe, K, Mg, Mn, Na, P, S, Zn, Co, Mo, Ni, and Se) in pea seeds. A panel of 482 genetically variable pea accessions was grown in field trials for
Hatice Sari, Clarice J. Coyne, Michael A. Grusak, Veselina A. Valkov, Zhiwu Zhang, Rebecca J. McGee, Yu Ma, Dorrie Main, Nonoy Bandillo, Jonah Hart, Britton M. Bourland, Renan Uhdre, Marilyn L. Warburton   +12 more
wiley   +1 more source

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum [PDF]

, 2011
Some nascent proteins that fold within the endoplasmic reticulum (ER) never reach their native state. Misfolded proteins are removed from the folding machinery, dislocated from the ER into the cytosol, and degraded in a series of pathways collectively ...
Ploegh, Hidde, Smith, Melanie H., Weissman, Jonathan S.   +2 more
core   +1 more source

Adenosine Triphosphatase Activities of Muscle Sarcolemma

Journal of Biological Chemistry, 1973
Abstract Isolated sarcolemma hydrolyzed ATP in the presence of Mg2+ and Ca2+. MgATPase was stimulated by low concentrations of Ca2+ and inhibited by high concentrations of this cation. Membranes hydrolyzed p-nitrophenylphosphate in the presence of Mg2+; this activity was stimulated by Ca2+ and K+.
George I. Drummond, David C. Ng, Prakash V. Sulakhe   +2 more
openaire   +3 more sources