Results 111 to 120 of about 70,698 (266)

Reporting adverse events of COVID-19 vaccines: The case of Bulgaria

PLoS ONE, 2022
As a member state of the European Union, where vaccines against COVID-19 are available and affordable, Bulgaria reports the lowest immunization coverage and the most pronounced vaccine distrust. The present study aimed to assess the self-reported adverse
Vanya Rangelova, Ralitsa Raycheva, Sara Sariyan, Ani Kevorkyan   +3 more
doaj  

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang   +4 more
wiley   +1 more source

Adenoviral vectors: not to be sneezed at [PDF]

Gene Therapy, 1998
P F, Searle, V, Mautner
openaire   +2 more sources

DNA Immunotherapy (INO‐3107) Long‐Term Efficacy Supported by Enhanced Immunogenicity in HPV‐6/11 RRP

The Laryngoscope, EarlyView.
Adults with HPV‐6/11‐associated recurrent respiratory papillomatosis (RRP) received DNA immunotherapy INO‐3107 in a Phase 1/2 trial and were followed for one year, with additional clinical follow‐up in a long‐term extension. INO‐3107 was shown to generate increased HPV‐directed T‐cell responses in Year 1 and substantially reduced surgical procedures ...
Milan R. Amin, Peter C. Belafsky, Simon R. Best, Aaron D. Friedman, Adam M. Klein, David G. Lott, Ted Mau, Randal C. Paniello, Seth M. Pransky, Nabil F. Saba, Stefani A. Slog, Elisabeth Gillespie, Christopher Welsh, Michael Dallas, Matthew P. Morrow, Jeffrey M. Skolnik   +15 more
wiley   +1 more source

On the likelihood of the individuals vaccinated with the adenoviral vector-based COVID-19 vaccines to develop vaccine-induced immune thrombotic thrombocytopenia being infected with adenovirus

Discover Viruses
Adenoviral vectors represent effective vaccine agents for various infectious diseases by eliciting a robust humoral and cellular immune response, which prompted their utilization during the COVID-19 pandemic.
Nawal Abd El-Baky, Alberto Rubio-Casillas, Vladimir N. Uversky, Elrashdy M. Redwan   +3 more
doaj   +1 more source

Reactivation of presumed adenoviral keratitis after laser in situ keratomileusis

, 2002
We report a patient with reactivation of presumed adenoviral keratoconjunctivitis after laser in situ keratomileusis (LASIK) to correct high myopia. The preoperative refraction was -13.00 diopters (D) in the right eye and -14.00 D in the left eye, and ...
Gurelik, G, Bilgihan, K, Hasanreisoglu, B, Safak, N, Ozdek, ŞENGÜL   +4 more
core   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Characterization of RISC-Associated Adenoviral Small RNAs

, 2011
RNA interference (RNAi) plays novel roles in both host antiviral defense and viral replication. It has been shown that some viruses can exploit the RNAi machinery for their own benefit by encoding for their own viral small RNAs.
Akusjärvi, Göran,, Xu, Ning, Ning Xu, Göran Akusjärvi   +3 more
core   +1 more source

Rapid and Efficient Affinity Isolation of Engineered Extracellular Vesicles Encapsulating Functional Proteins via Internal Twin‐Strep Tetraspanin Tagging

Small, EarlyView.
Structure‐guided internal twin‐Strep tagging of the tetraspanins CD63 or CD9 enables rapid and efficient antibody‐free affinity isolation of engineered extracellular vesicles (EVs) using Strep technology while allowing luminal protein loading. The approach removes over 96% of contaminants, separates tagged EVs from coexisting viral particles, and ...
Minh‐Tu Pham, Jona Benjamin Krohn, Janis Meyer, Christian Ritter, Martin Schneider, Dominic Helm, Dario Frey, Kleopatra Rapti, Uta Haselmann‐Weiss, Elif Toprak, Viet Loan Dao Thi, Florian Leuschner, Dirk Grimm, Karl Rohr, Ralf Bartenschlager   +14 more
wiley   +1 more source

Adenoviral vector-based vaccine against enterovirus infection

[[abstract]]The present invention relates to a recombinant adenoviral vector for generating immunity against enterovirus infection. In one embodiment, the recombinant adenoviral vector of the invention comprises an expression cassette encoding a PI ...
Chow, YH;Tsou, YL;Chong, PCS
core