Results 51 to 60 of about 35,783 (166)

Role of homologous recombination/recombineering on human adenovirus genome engineering: Not the only but the most competent solution

Engineering Microbiology
Adenoviruses typically cause mild illnesses, but severe diseases may occur primarily in immunodeficient individuals, particularly children. Recently, adenoviruses have garnered significant interest as a versatile tool in gene therapy, tumor treatment ...
Lisa-Marie Dawson, Montaha Alshawabkeh, Katrin Schröer, Fatima Arakrak, Anja Ehrhardt, Wenli Zhang   +5 more
doaj   +1 more source

Preclinical assessment of viral vectored and protein vaccines targeting the Duffy-binding protein region II of Plasmodium vivax

Frontiers in Immunology, 2015
Malaria vaccine development has largely focused on Plasmodium falciparum; however a reawakening to the importance of P. vivax has spurred efforts to develop vaccines against this difficult to treat and at times severe form of relapsing malaria, which ...
Simone C de Cassan, A. Rushdi Shakri, David eLlewellyn, Sean C Elias, Jee Sun Cho, Jee Sun Cho, Anna L Goodman, Jing eJin, Alexander D Douglas, Rossarin eSuwanarusk, Rossarin eSuwanarusk, François H Nosten, Laurent eRénia, Laurent eRénia, Bruce eRussell, Chetan E Chitnis, Chetan E Chitnis, Simon J Draper   +17 more
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Are adenoviruses zoonotic? A systematic review of the evidence

Emerging Microbes and Infections, 2019
Adenoviruses (AdVs) are major contributors to clinical illnesses. Novel human and animal AdVs continue to be identified and characterized. Comparative analyses using bioinformatic methods and Omics-based technologies allow insights into how these human ...
Laura K. Borkenhagen, Jane K. Fieldhouse, Donald Seto, Gregory C. Gray   +3 more
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Rapid detection of human adenovirus by multiple cross displacement amplification combined with nanoparticle-based biosensor platform

Sensors and Actuators Reports
Human adenoviruses (HAdV), particularly serotypes 3 and 7 (HAdV-3 and HAdV-7), are significant respiratory pathogens that contribute to high morbidity rates and severe pneumonia in infants and children.
Linglong Wan, Xiaolan Huang, Jin Fu, Fei Xiao, Nan Jia, Yu Zhang, Min Chen, Xiong Zhu, Shijun Li, Juan Zhou, Yi Wang   +10 more
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Systemic Infection with Enteric Adenovirus in Immunocompetent Child with Haemophilus influenzae Disease

Emerging Infectious Diseases, 2009
Nino Khetsuriani, Suxiang Tong, Xiaoyan Lu, Shannon Reed, Dean D. Erdman, Angela P. Campbell, Krongkaew Supawat, Sahas Liamsuwan, Narayanan Jothikumar, Sonja J. Olsen   +9 more
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Human adenoviruses in children with gastroenteritis: a systematic review and meta-analysis

BMC Infectious Diseases
Purpose Human adenoviruses (HAdVs) have always been suggested as one of the main causes of gastroenteritis in children. However, no comprehensive report on the global epidemiology of these viruses in pediatric gastroenteritis is available.
Pegah Khales, Mohammad Hossein Razizadeh, Saied Ghorbani, Afagh Moattari, Jamal Sarvari, Hassan Saadati, Shirin Sayyahfar, Zahra Salavatiha, Morteza Haghighi Hasanabad, Vahdat Poortahmasebi, Ahmad Tavakoli   +10 more
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Metagenomic and transcriptomic investigation of pediatric acute liver failure cases reveals a common pathway predominated by monocytes

mBio
In 2022, a cluster of severe childhood hepatitis was detected primarily in Europe and North America, leading to a global alert by the World Health Organization.
Ruben H. de Kleine, Ellen C. Carbo, Willem S. Lexmond, Xuewei W. Zhou, Alicia de Kroon, Hailiang Mei, Sander T. H. Bontemps, Rick Hennevelt, Lilli Gard, Igor A. Sidorov, Stefan A. Boers, Marius C. van den Heuvel, Emilie P. Buddingh, Aloys C. M. Kroes, Vincent E. de Meijer, Elisabeth H. Schölvinck, Karin J. von Eije, Simon P. Jochems, Jutte J. C. de Vries   +18 more
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Epidemiology of Human Adenoviruses: A 20-Year Retrospective Observational Study in Hospitalized Patients in Bern, Switzerland

Clinical Epidemiology, 2020
Joyce Odeke Akello,1– 3 Richard Kamgang,1 Maria Teresa Barbani,1 Franziska Suter-Riniker,1 Stephen L Leib,1 Alban Ramette1 1Institute for Infectious Diseases, University of Bern, Bern, Switzerland; 2Biology Division, Spiez Laboratory, Swiss Federal
Akello JO, Kamgang R, Barbani MT, Suter-Riniker F, Leib SL, Ramette A   +5 more
doaj  

Whole genome-based surveillance for human adenovirus-related diseases in Kobe City, Japan, 2018–2022

BMC Research Notes
Background Human adenoviruses (HAdVs) cause various diseases, and they frequently undergo recombination. As adenoviruses are susceptible to recombination, whole-genome sequencing and analysis are essential approaches to understanding viral properties. In
Yoshihiko Tanimoto, Minori Ohyama, Erika Ito, Kyoko Akiyoshi, Yuka Onishi, Ai Mori, Ryohei Nomoto   +6 more
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Hybrid sequencing for detailed genetic characterization of human adenoviruses

Scientific Reports
Human adenoviruses (HAdVs) are highly contagious and have significant clinical implications in the pediatric population. In the present study, we employed a combination of long-read sequencing and short-read sequencing to accurately reconstruct 32 ...
Bin Fang, Juan Lai, Yongfeng Liu, Lin-lin Liu, Xiao Yu, Xiang Li, Haili Ke, Xianfeng Zhang, Xin Zhang   +8 more
doaj   +1 more source