Results 41 to 50 of about 35,783 (166)

Structure-derived insights from blood factors binding to the surfaces of different adenoviruses

Nature Communications
The tropism of adenoviruses (Ads) is significantly influenced by the binding of various blood factors. To investigate differences in their binding, we conducted cryo-EM analysis on complexes of several human adenoviruses with human platelet factor-4 (PF4)
Haley E. Mudrick, Shao-Chia Lu, Janarjan Bhandari, Mary E. Barry, Jack R. Hemsath, Felix G. M. Andres, Olivia X. Ma, Michael A. Barry, Vijay S. Reddy   +8 more
doaj   +1 more source

Serological and Molecular Biological Studies of Parvovirus B19, Coxsackie B Viruses, and Adenoviruses as Potential Cardiotropic Viruses in Bulgaria

Folia Medica, 2016
Background: Inflammatory diseases of the heart (myocarditis, pericarditis) are commonly caused by viruses. Among the human cardiotropic viruses, parvovirus B19, Coxsackie B viruses, and adenoviruses play a leading role.
Ivanova Stefka Kr., Angelova Svetla G., Stoyanova Asya P., Georgieva Irina L., Nikolaeva-Glomb Lubomira K., Mihneva Zafira G., Korsun Neli St.   +6 more
doaj   +1 more source

Temporal changes in respiratory adenovirus serotypes circulating in the greater Toronto area, Ontario, during December 2008 to April 2010

Virology Journal, 2013
Background Certain adenovirus serotypes cause severe infections, especially in children. It is important to monitor temporal changes in serotypes causing clinical disease.
Abbas Kaniza Zahra, Lombos Ernesto, Duvvuri Venkata R, Olsha Romy, Higgins Rachel R, Gubbay Jonathan B   +5 more
doaj   +1 more source

Establishment of a novel cell line for producing replication-competent adenovirus-free adenoviruses

BMC Biotechnology
Adenoviruses are commonly utilized as viral vectors for gene therapy, genetic vaccines, and recombinant protein expression. To generate replication-defective adenoviruses, E1-complementing cell lines such as HEK293A are utilized; however, limitations ...
Eun Yeong Han, Yeon-Jeong Kim
doaj   +1 more source

First description of gastroenteritis viruses in Lebanese children: A pilot study

Journal of Infection and Public Health, 2011
Summary: Human enteric viruses are important causes of acute gastroenteritis in infants and children. The role of rotaviruses, adenoviruses, human caliciviruses and astroviruses in the development of severe acute gastroenteritis requiring hospitalization
Randa Meraabi Al-Ali, Wassim Chehadeh, Monzer Hamze, Fouad Dabboussi, Sani Hlais, Hassan Mallat   +5 more
doaj   +1 more source

Evidence of frequent recombination among human adenoviruses

Journal of General Virology, 2008
Genome stability is a prerequisite for the production and use of adenoviruses for therapy of genetic diseases and cancer. To test the premise that the adenoviral genome is stable, the phylogenetic relationships of 16 adenovirus C (AdC) field isolates were studied in four genome regions: hexon, fiber, polymerase and E1A.
Alexander N, Lukashev, Olga E, Ivanova, Tatiana P, Eremeeva, Richard D, Iggo   +3 more
openaire   +2 more sources

Isolation of a novel monkey adenovirus reveals a new phylogenetic clade in the evolutionary history of simian adenoviruses

Virology Journal, 2011
Adenoviruses of primates include human (HAdV) and simian (SAdV) isolates classified into 8 species (Human Adenovirus A to G, and Simian Adenovirus A).
Bofill-Mas Silvia, Almeida Francisca C, Hundesa Ayalkibet, Maluquer de Motes Carlos, Girones Rosina   +4 more
doaj   +1 more source

Expanding the Scope of Adenoviral Vectors by Utilizing Novel Tools for Recombination and Vector Rescue

Viruses
Recombinant adenoviruses are widely used in clinical and laboratory applications. Despite the wide variety of available sero- and genotypes, only a fraction is utilized in vivo.
Julian Fischer, Ariana Fedotova, Clara Bühler, Laura Darriba, Sabrina Schreiner, Zsolt Ruzsics   +5 more
doaj   +1 more source

CryoEM structure of adenovirus type 3 fibre with desmoglein 2 shows an unusual mode of receptor engagement

Nature Communications, 2019
Human adenoviruses (HAd) cause respiratory, gastrointestinal and ocular infections. Here, the authors provide insights into the early stages of adenovirus infection by determining the cryo-EM structure of the trimeric HAd type 3 fibre knob bound to its ...
Emilie Vassal-Stermann, Gregory Effantin, Chloe Zubieta, Wim Burmeister, Frédéric Iseni, Hongjie Wang, André Lieber, Guy Schoehn, Pascal Fender   +8 more
doaj   +1 more source

Adenovirus-Mediated Expression of Dengue Virus 2 Envelope Ferritin Nanoparticles Induced Virus-Specific Immune Responses in BALB/c Mice

Microbiology Research
This study provides a preliminary background for the development of a viral vector vaccine for the dengue virus using genetic material encoded by dengue envelope ferritin nanoparticles.
M.S.B.W.T.M. Nipuna Sudaraka Tennakoon, Ji-Hoon Ryu, Yong-Sam Jung, Yingjuan Qian, Hyun-Jin Shin   +4 more
doaj   +1 more source