Results 31 to 40 of about 35,783 (166)

Molecular evolution of human species D adenoviruses [PDF]

Infection, Genetics and Evolution, 2011
Adenoviruses are medium-sized double stranded DNA viruses that infect vertebrates. Human adenoviruses cause an array of diseases. Currently there are 56 human adenovirus types recognized and characterized within seven species (A-G). Of those types, a majority belongs to species D.
Christopher M, Robinson, Donald, Seto, Morris S, Jones, David W, Dyer, James, Chodosh   +4 more
openaire   +2 more sources

Double suicide genes selectively kill human umbilical vein endothelial cells

Virology Journal, 2011
Background To construct a recombinant adenovirus containing CDglyTK double suicide genes and evaluate the killing effect of the double suicide genes driven by kinase domain insert containing receptor (KDR) promoter on human umbilical vein endothelial ...
Liu Lunxu, Wang Yanping, Mei Longyong, Jia Weiguo, Che Guowei   +4 more
doaj   +1 more source

Predicting the Next Eye Pathogen: Analysis of a Novel Adenovirus

mBio, 2013
For DNA viruses, genetic recombination, addition, and deletion represent important evolutionary mechanisms. Since these genetic alterations can lead to new, possibly severe pathogens, we applied a systems biology approach to study the pathogenicity of a ...
Christopher M. Robinson, Xiaohong Zhou, Jaya Rajaiya, Mohammad A. Yousuf, Gurdeep Singh, Joshua J. DeSerres, Michael P. Walsh, Sallene Wong, Donald Seto, David W. Dyer, James Chodosh, Morris S. Jones   +11 more
doaj   +1 more source

Functional prediction of hypothetical proteins in human adenoviruses [PDF]

Bioinformation, 2015
Assigning functional information to hypothetical proteins in virus genomes is crucial for gaining insight into their proteomes. Human adenoviruses are medium sized viruses that cause a range of diseases. Their genomes possess proteins with uncharacterized function known as hypothetical proteins. Using a wide range of protein function prediction servers,
Dorden, Shane, Mahadevan, Padmanabhan
openaire   +2 more sources

In vitro and in vivo tropism and biodistribution of recombinant simian adenovirus type 25

Журнал микробиологии, эпидемиологии и иммунобиологии
Introduction. Recombinant adenoviruses are widely used in the development of vaccines for a variety of infectious diseases. Despite numerous clinical studies, only a few types of human (types 5 and 26) and simian (isolate Y25) adenoviruses are currently ...
Irina V. Vavilova, Tatiana A. Ozharovskaia, Olga V. Zubkova, Olga Popova, Daria V. Voronina, Polina P. Goldovskaya, Denis I. Zrelkin, Alina Sh. Dzharullaeva, Inna V. Dolzhikova, Dmitry V. Shcheblyakov, Denis Yu. Logunov, Alexander L. Gintsburg   +11 more
doaj   +1 more source

Prevalence of human respiratory syncytial virus, parainfluenza and adenoviruses in East Africa Community partner states of Kenya, Tanzania, and Uganda: A systematic review and meta-analysis (2007-2020).

PLoS ONE, 2021
BackgroundViruses are responsible for a large proportion of acute respiratory tract infections (ARTIs). Human influenza, parainfluenza, respiratory-syncytial-virus, and adenoviruses are among the leading cause of ARTIs.
Therese Umuhoza, Wallace D Bulimo, Julius Oyugi, Jean Pierre Musabyimana, Alison A Kinengyere, James D Mancuso   +5 more
doaj   +1 more source

Comparative Effect of Oncolytic Adenoviruses with E1 A or E113-55 kDa Deletions in Malignant Gliomas

Neoplasia: An International Journal for Oncology Research, 2005
Replication-competent oncolytic adenoviruses hold considerable promise for treating malignant gliomas. The toxicity of the clinically tested Ell B-55 kDa mutant virus is negligible; however, its full clinical potential is still being evaluated.
Hong Jiang, Candelaria Gomez-Manzano, Ramon Alemany, Diana Medrano, Marta Alonso, B. Nebiyou Bekele, E Lin, Charles C. Conrad, W.K. Alfred Yung, Juan Fueyo   +9 more
doaj   +1 more source

Infectivity period of mice inoculated with human adenoviruses [PDF]

Laboratory Animals, 2011
Due to non-productive infections, mice are not a good model to study some human adenoviruses. However, mice provide an excellent model to study the metabolic effects of human adenovirus, Ad36. Research interest in Ad36 is increasing rapidly, and consequently an increase in the use of mice as a model is anticipated.
Rashmi, Krishnapuram, Heather, Kirk-Ballard, Aamri, Zuberi, Nikhil V, Dhurandhar   +3 more
openaire   +2 more sources

Oncolytic adenoviruses as a therapeutic approach for osteosarcoma: A new hope

Journal of Bone Oncology, 2017
Osteosarcoma is the most common bone cancer among those with non-hematological origin and affects mainly pediatric patients. In the last 50 years, refinements in surgical procedures, as well as the introduction of aggressive neoadjuvant and adjuvant ...
Marc Garcia-Moure, Naiara Martinez-Vélez, Ana Patiño-García, Marta M. Alonso   +3 more
doaj   +1 more source

Quantification of Human Adenoviruses in European Recreational Waters [PDF]

Food and Environmental Virology, 2010
The presence of human adenoviruses in recreational water might cause disease in the population upon exposure. Human adenoviruses detected by PCR could also serve as indicators of the virological water quality. In order to assess the applicability of human adenoviruses to the evaluation of the faecal contamination in European bathing waters, a real-time
BOFILL MAS S, CALGUA B, CLEMENTE CASARES P, LA ROSA G, IACONELLI M, MUSCILLO M, RUTJES S, DE RODA HUSMAN AM, GRUNERT A, GRABER I, VERANI, MARCO, CARDUCCI, ANNALAURA, CALVO M, WYN JONES P, GIRONES R.   +14 more
openaire   +2 more sources