Results 31 to 40 of about 35,791 (265)
Construction and characterization of recombinant human adenovirus type 5 expressing foot-and-mouth disease virus capsid proteins of Indian vaccine strain, O/IND/R2/75 [PDF]
Veterinary World, 2015 Aim: Generation of recombinant human adenovirus type 5 expressing foot-and-mouth disease virus (FMDV) capsid protein genes along with full-length 2B, 3B and 3Cpro and its characterization.
Ramesh Kumar +2 more
doaj +1 more source
Chimpanzee Adenovirus Antibodies in Humans, Sub-Saharan Africa
Emerging Infectious Diseases, 2006 Human sera from the United States, Thailand, and sub-Saharan Africa and chimpanzee sera were tested for neutralizing antibodies to 3 chimpanzee adenoviruses.
Zhiquan Xiang +7 more
doaj +1 more source
Pyrogenicity of human adenoviruses
Journal of General Virology, 2000 High doses (>1·56×107 p.f.u.) of purified preparations of human adenovirus types 3, 5 and 8 exhibited definite pyrogenic activity when injected intravenously into rabbits. Complete pyrogenic tolerance was obtained not only with homologous types but also with heterologous types of adenovirus.
openaire +2 more sources
Chimpanzee adenoviral vectors as vaccines – challenges to move the technology into the fast lane
Expert Review of Vaccines, 2017 Introduction: In recent years, replication-defective chimpanzee-derived adenoviruses have been extensively evaluated as genetic vaccines. These vectors share desirable properties with human adenoviruses like the broad tissue tropism and the ease of large-
Alessandra Vitelli +5 more
doaj +1 more source
Molecular Therapy: Oncolytics, 2020 Neuroblastoma (NB) is a primary malignant tumor of the peripheral sympathetic nervous system. High-risk NB is characterized by MYCN amplification and human telomerase reverse transcriptase (hTERT) rearrangement, contributing to hTERT activation and a ...
Terutaka Tanimoto +9 more
doaj +1 more source
Humoral immune response to adenovirus induce tolerogenic bystander dendritic cells that promote generation of regulatory T cells. [PDF]
PLoS Pathogens, 2018 Following repeated encounters with adenoviruses most of us develop robust humoral and cellular immune responses that are thought to act together to combat ongoing and subsequent infections.
Thi Thu Phuong Tran +7 more
doaj +1 more source
Characteristics of Noncultivable Adenoviruses Associated with Diarrhea in Infants: A New Subgroup of Human Adenoviruses [PDF]
Journal of Clinical Microbiology, 1979 Virus particles morphologically resembling adenovirus were found in fecal specimens from infants and were examined for cultivability with standard cell culture techniques and for characteristics of human adenoviruses. Specimens from 13 of 15 infants could not be cultivated in cell cultures.
G W, Gary, J C, Hierholzer, R E, Black
openaire +2 more sources
Journal for ImmunoTherapy of Cancer, 2018 Background Oncolytic viruses are currently experiencing accelerated development in several laboratories worldwide, with some forty-seven clinical trials currently recruiting.
Janet Lei +11 more
doaj +1 more source
Neoplasia: An International Journal for Oncology Research, 2005 Oncolytic adenoviruses are being tested as potential therapies for human malignant tumors, including gliomas. Here we report for the first time that a mutation in the E1A gene results in low levels of ElA protein, conditioning the replication of mutant ...
Hong Jiang +10 more
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source