Results 111 to 120 of about 35,780 (254)
Cellular localization of the Mn2+‐dependent adenylyl cyclase (AC) in rat testis [PDF]
, 1981 Jan O. Gordeladze +4 more
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Mitochondrial control of ciliary gene expression and structure in striatal neurons
The Journal of Physiology, EarlyView.Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen +5 more
wiley +1 more source
Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.ABSTRACT Multiple muscarinic M4 receptor modulators are currently advancing in clinical development for the treatment of positive symptoms in schizophrenia, including agonists and positive allosteric modulators. Considering the importance of comprehending M4 receptor pharmacology for these therapeutic applications, this study investigates M4 receptor ...
Madeleine Merz +5 more
wiley +1 more source
Cholera Toxin Action on Rabbit Corpus Luteum Membranes: Effects on Adenylyl Cyclase Activity and Adenosine Diphospho-ribosylation of the Stimulatory Guanine Nucleotide-binding Regulatory Component1 [PDF]
, 1985 Anne N. Hirshfield
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British Journal of Pharmacology, Volume 182, Issue 12, Page 2803-2820, June 2025.Background and Purpose Myeloid‐derived suppressor cells (MDSCs) play important roles in the pathogenesis of asthma. Recent studies demonstrate that their function can be modulated by different pharmacological approaches. In this study, we focussed on the effects of systemically administered prostaglandin EP4 receptor agonist L‐902,688 and pegylated ...
Tim Lange +7 more
wiley +1 more source
Journal of Pharmacological Sciences, 2004 We previously reported that sphingosine 1-phosphate (S1P) induces inhibition of adenylyl cyclase and activation of phospholipase C via independent G protein-coupled receptors in adult rat hepatocytes.
Dong-Soon Im +4 more
doaj
Obesity, White Adipose Tissue, and Adipokines Signaling in Male Reproduction
Molecular Nutrition &Food Research, Volume 69, Issue 10, May 2025.Role of adipokines in the hypothalamic‐pituitary‐gonadal axis (HPG) during obesity. Obesity induces structural and functional changes in WAT, with a consequent imbalance in the production and secretion of adipokines. While the adipokines adiponectin and omentin‐1 are downregulated, the adipokines leptin, resistin, vifastin, apelin, and chemerin are ...
Fabiane Ferreira Martins +6 more
wiley +1 more source
A Dominant Mutation in Gαs‐Protein Increases Hair Pigmentation
Pigment Cell &Melanoma Research, Volume 38, Issue 3, May 2025.ABSTRACT We have identified a chemically induced mouse mutation which increases the eumelanic hair pigmentation. We identify a coding mutation, A3533G, resulting in an amino acid substitution Y1133C, in the Gnas gene encoding the Gαs subunit of the tripartite G‐protein, consistent with an activation of signalling via MC1R.
Philip S. Goff +8 more
wiley +1 more source
Quantitative stoichiometry of the proteins of the stimulatory arm of the adenylyl cyclase cascade in neuroblastoma x glioma hybrid, NG108-15 cells [PDF]
, 1994 Gun‐Do Kim +2 more
openalex +1 more source