Severe Hypoxia Reduces Adenylyl Cyclase 6 Expression and Function in Bronchial Epithelial Cells. [PDF]
Cunnington RH +5 more
europepmc +1 more source
Synergistic Interplay of Stimulatory Cofactors in the Activation of Adenylyl Cyclase Isoform 1. [PDF]
Li T, Krishnan S, Hicks T, Li J.
europepmc +1 more source
Biochemical characterization of the full-length isoform of soluble adenylyl cyclase. [PDF]
Ferreira J +3 more
europepmc +1 more source
Sustained soluble adenylyl cyclase (sAC)-generated cAMP is necessary and sufficient for hyperactivated motility in human sperm. [PDF]
Ritagliati C +3 more
europepmc +1 more source
Inhibition of adenylyl cyclase 1 or exchange protein activated by cAMP restores ATP-sensitive potassium channel activity after chronic opioid exposure. [PDF]
Klein AH +9 more
europepmc +1 more source
\(\bf Aims\) In contrast to the membrane bound adenylyl cyclases, the soluble adenylyl cyclase (sAC) is activated by bicarbonate and divalent ions including calcium. sAC is located in the cytosol, nuclei and mitochondria of several tissues including cardiac muscle. However, its role in cardiac pathology is poorly understood. Here we investigate whether
Schirmer, Ilona +11 more
openaire +1 more source
Characterization of the regulatory properties of mammalian adenylyl cyclase.
Intracellular concentrations of the ubiquitous second messenger cyclic adenosine monophosphate (cAMP) are primarily controlled at the level of its synthesis by adenylyl cyclase (AC) and regulate a number of physiological processes including cell growth ...
Zimmermann, Gregor
core
Lipid regulation of adenylyl cyclase Rv1625c from Mycobacterium tuberculosis by its membrane-domain receptor. [PDF]
Schultz ACF +3 more
europepmc +1 more source
Opioid Receptor Mechanisms Contributing to Dependence and Adenylyl Cyclase Sensitization.
At the cellular level, opioid dependence can be characterized by a compensatory enhancement of adenylyl cyclase activity which is revealed as a withdrawal response by an increase in stimulated cAMP accumulation.
Divin, Mary Falgout
core
Photoactivated adenylyl cyclase in cortical astrocytes promotes synaptic potentiation and reveals alterations in Huntington's disease. [PDF]
Sitjà-Roqueta L +21 more
europepmc +1 more source

